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Study: Biomarkers may aid in early diagnosis of breast cancer

Using a new, powerful method for rapidly screening molecules associated with disease, proteomics expert Joshua LaBaer and colleagues from the Biodesign Institute at Arizona State University have identified a broad panel of 28 early predictors, or biomarkers, that may one day aid in the early diagnosis of breast cancer.

17 Dec 2010

New study suggests PSA test effective for men with prostate cancer

The PSA screening test for prostate cancer is not perfect. It can indicate cancer when none is present and miss life-threatening tumors. But a new study suggests the test is more reliable in men taking dutasteride (Avodart®), a drug widely prescribed to shrink an enlarged prostate gland.

17 Dec 2010

GSK, Impax enter global development, commercialization agreement for PD investigational product, IPX066

GlaxoSmithKline (GSK) and Impax Pharmaceuticals, the brand products division of Impax Laboratories, Inc. (Impax), today announced an agreement for the development and commercialization of IPX066, Impax's novel extended release carbidopa-levodopa product, outside the United States and Taiwan. IPX066, an investigational product under development for the treatment of Parkinson's Disease (PD), is currently in Phase III clinical trials.

17 Dec 2010

Amygdala plays central role in generating fear reactions in humans too

A new study, published online on December 16 in Current Biology, a Cell Press publication, offers new insight into the emotional life of a unique individual who completely lacks the function of an almond-shaped structure in the brain known as the amygdala. Studies over the last 50 years have shown that the amygdala plays a central role in generating fear reactions in animals from rats to monkeys.

17 Dec 2010

FDA approves Neuralstem's IND to initiate NSI-189 Phase Ia safety trial in major depression

Neuralstem, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved its Investigational New Drug (IND) application to initiate a Phase Ia safety trial to test NSI-189, its first small molecule compound, in major depression. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in depression and other diseases, such as Alzheimer's disease.

17 Dec 2010

Head, neck radiation exposure increases thyroid cancer in children

When children are exposed to head and neck radiation, whether due to cancer treatment or multiple diagnostic CT scans, the result is an increased risk of thyroid cancer for the next 58 years or longer, according to University of Rochester Medical Center research.

17 Dec 2010

Study: Natural high hemoglobin levels safe for kidney disease patients on dialysis

Naturally occurring high hemoglobin levels are safe for kidney disease patients on dialysis, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

17 Dec 2010

High-dose rate brachytherapy procedure to treat prostate cancer

Beaumont Hospital radiation oncologists have launched a research study to treat men with low to intermediate risk prostate cancer with a single dose of radiation.

17 Dec 2010

Scientists decipher genetic code for pediatric medulloblastoma

Scientists at the Johns Hopkins Kimmel Cancer Center have deciphered the genetic code for medulloblastoma, the most common pediatric brain cancer and a leading killer of children with cancer.

16 Dec 2010

Researchers discover allium vegetable consumption may lower hip osteoarthritis

Researchers at King's College London and the University of East Anglia have discovered that women who consume a diet high in allium vegetables, such as garlic, onions and leeks, have lower levels of hip osteoarthritis

16 Dec 2010

FDA issues CRL for AstraZeneca's ticagrelor NDA

AstraZeneca announced today that the US Food and Drug Administration (FDA) has issued a complete response letter (CRL) for the New Drug Application (NDA) for ticagrelor (BRILINTA™).

16 Dec 2010

Researchers begin placebo-controlled trial to test drug treatment for Rett syndrome

Researchers at Children's Hospital Boston have begun a randomized, placebo-controlled trial to test a potential drug treatment for Rett syndrome, the leading known genetic cause of autism in girls.

16 Dec 2010

Study reveals immune cell provides new therapeutic strategy for SLE

A new study provides fascinating insight into the underlying pathology associated with the autoimmune disease, systemic lupus erythematosus.

16 Dec 2010

Stem cell therapy gives sight to four year old

Izabelle Evans, only four years of age, was born blind but in a medical miracle has been given sight. After a stem cell treatment in China she can see. Her parents James Evans and Hollie McHugh are “over the moon” that their daughter can finally see them. As of now she can see only 3ft away. The treatment that cost the family £50,000.

16 Dec 2010

Genome is one more factor to blame for unwanted pounds

In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the fact that we no longer live in the Stone Age.

16 Dec 2010

Manhattan Pharmaceuticals reports preliminary results from AST-915 Phase 1/2 study in essential tremor

Manhattan Pharmaceuticals, Inc. announced preliminary results today from a Phase 1/2 study of AST-915 for the treatment of essential tremor. Data from this single dose study demonstrated that AST-915 was safe and well tolerated and demonstrated a clear effect on tremor power.

16 Dec 2010

Web-based screening tools for determining TBI or PTS among military service members

Military service members from the Iraq and Afghanistan wars attending this week's 6th annual Road to Recovery Conference and Tribute at Walt Disney World are being given access to two web-based screening tools that enable them to quickly and confidentially determine if they might have suffered a Traumatic Brain Injury (TBI) or have Post-Traumatic Stress (PTS). The three day event is being co-presented by the Coalition to Salute America's Heroes and The American Legion.

16 Dec 2010

Discovery Labs awarded NIH Fast Track SBIR grant for developing aerosolized KL4 surfactant for RDS

Discovery Laboratories, Inc. today announced that the Company has been awarded Phase I of a Fast Track Small Business Innovation Research Grant (SBIR) from the National Institutes of Health (NIH) to support the development of the Company's program for aerosolizing KL4 surfactant for neonatal respiratory distress syndrome (RDS).

16 Dec 2010

RFA highly valuable therapy for controlling cancerous nodules

Researchers from Italy determined that radiofrequency ablation (RFA) is a safe and effective therapy for managing hepatocellular carcinoma (HCC) in cirrhotic patients. The high repeatability of RFA is advantageous in controlling recurrences of cancerous tumors in the liver. Results of this 10-year retrospective study are available in the January 2011 issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

16 Dec 2010

Omega-3 EPA or combination of EPA and DHA provide clear antidepressant benefits

Researchers at the University of Illinois at Chicago completed a review of previously published research on antidepressant benefits of Omega-3 essential fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The review comprised a meta-analysis of 15 randomized, double-blind, placebo-controlled studies in patients with depression and results were presented at the recent annual meeting of the American College of Neuropsychopharmacology.

16 Dec 2010

Medical Condition News

Study: Biomarkers may aid in early diagnosis of breast cancer

New study suggests PSA test effective for men with prostate cancer

GSK, Impax enter global development, commercialization agreement for PD investigational product, IPX066

Amygdala plays central role in generating fear reactions in humans too

FDA approves Neuralstem's IND to initiate NSI-189 Phase Ia safety trial in major depression

Head, neck radiation exposure increases thyroid cancer in children

Study: Natural high hemoglobin levels safe for kidney disease patients on dialysis

High-dose rate brachytherapy procedure to treat prostate cancer

Scientists decipher genetic code for pediatric medulloblastoma

Researchers discover allium vegetable consumption may lower hip osteoarthritis

FDA issues CRL for AstraZeneca's ticagrelor NDA

Researchers begin placebo-controlled trial to test drug treatment for Rett syndrome

Study reveals immune cell provides new therapeutic strategy for SLE

Stem cell therapy gives sight to four year old

Genome is one more factor to blame for unwanted pounds

Manhattan Pharmaceuticals reports preliminary results from AST-915 Phase 1/2 study in essential tremor

Web-based screening tools for determining TBI or PTS among military service members

Discovery Labs awarded NIH Fast Track SBIR grant for developing aerosolized KL4 surfactant for RDS

RFA highly valuable therapy for controlling cancerous nodules

Omega-3 EPA or combination of EPA and DHA provide clear antidepressant benefits

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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