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Insulin-sensitizing drugs may offer new treatments for kidney failure

Evidence reported in the October issue of Cell Metabolism, a Cell Press publication, offers a completely new explanation for why people with diabetes account for more than half of all patients requiring dialysis or kidney transplantation. It appears that insulin has a significant influence on the structure and proper function of a particular group of very specialized cells, known as podocytes, that are integral to the kidney's ability to do its job filtering blood.

6 Oct 2010

Researchers discover biomarker for allergy can originate from mother

Allergies occur when the defence mechanisms of the immune system malfunction and misread normal substances entering the body as invading pathogens. Antibodies are part of our biochemical arsenal for combating viruses, bacteria, parasites and other alien substances, but during an allergic reaction the antibody, known as IgE, is directed against usually harmless substances such as grass pollen, nuts, pets or eggs. However, researchers from COPSAC (Copenhagen Studies on Asthma in Childhood) at the Faculty of Health Sciences, University of Copenhagen recently discovered indications that IgE in the blood of the umbilical cord could originate from the mother, and decided to conduct a focused study on this.

6 Oct 2010

Saneron receives grant to develop safety guidelines for transplanting HUBC cells in Alzheimer's disease

The National Institutes of Health has awarded a three-year, $2.6-million grant to the University of South Florida and Tampa-based biotechnology company Saneron-CCEL Therapeutics, Inc., to establish dosing and safety guidelines for transplanting human umbilical cord blood cells (HUBC) into animal models of Alzheimer's disease.

6 Oct 2010

Varian, IMRIS enter agreement to co-develop new MR-guided radiation therapy system for cancer

Varian Medical Systems, Inc., and IMRIS Inc. have concluded an agreement to co-develop an innovative new MR-guided radiation therapy system for use in treating a variety of cancers.

6 Oct 2010

Low level of testosterone increases risk for Alzheimer's disease

Low levels of the male sex hormone, testosterone, in older men is associated with the onset of Alzheimer's disease, according to research by a team that includes a Saint Louis University scientist.

6 Oct 2010

Amino acid mixture increases survival in mice

When mice are given drinking water laced with a special concoction of amino acids, they live longer than your average mouse, according to a new report in the October issue of Cell Metabolism, a Cell Press publication. The key ingredients in the supplemental mixture are so-called branched-chain amino acids, which account for 3 of the 20 amino acids (specifically leucine, isoleucine, and valine) that are the building blocks of proteins.

6 Oct 2010

ADRCs cells improve survival in acute kidney injury animal model

Preclinical data was published today on research performed by Cytori Therapeutics (NASDAQ:CYTX) showing adipose (fat)-derived stem and regenerative cells (ADRCs), either fresh or banked, demonstrated statistically significant improvements in animal survival and kidney function in an acute kidney injury animal model.

6 Oct 2010

IDMC recommends early termination of Phase 3 intramuscular depot aripiprazole trial

Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) announced today that an independent data monitoring committee (IDMC) has recommended the early termination of its Phase 3, 52-week, placebo-controlled, intramuscular depot aripiprazole trial.

6 Oct 2010

Fish oil induces severe colitis and colon cancer in mice

Fish oil - long encouraged by doctors as a supplement to support heart and joint health, among other benefits - induced severe colitis and colon cancer in mice in research led by Michigan State University and published this month in the journal Cancer Research.

6 Oct 2010

Researchers find exposure to air pollution increases severity of asthma symptoms

Exposure to dirty air is linked to decreased function of a gene that appears to increase the severity of asthma in children, according to a joint study by researchers at Stanford University and the University of California, Berkeley.

6 Oct 2010

Cancer cells utilize energy-rich intermediates of sugar metabolism: Research

Cancer research is facing a radical change of direction. Cancer cells do not obtain their energy from the breakdown of sugar to carbon dioxide and water, but from energy-rich intermediates of sugar metabolism instead.

6 Oct 2010

Novel invasive surgery for children with scoliosis may eliminate need for spinal fusion

A novel minimally invasive surgery for young children living with a difficult-to-treat progressive form of scoliosis, known as juvenile idiopathic scoliosis, may eliminate the need for spinal fusion later in adolescence, according to new research by surgeons from Children's Mercy Hospitals and Clinics in Kansas City, Mo. The study was presented at the American Academy of Pediatrics National Conference and Exhibition in San Francisco.

6 Oct 2010

Lixte, NCI collaborate for clinical evaluation of LB-100 compound

Lixte Biotechnology Holdings announced today that the National Cancer Institute Experimental Therapeutics (NExT) Program Senior Advisory Committee (SAC), Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI), National Institutes of Health (NIH), signed a NExT Material Transfer Agreement formalizing a collaboration with Lixte Biotechnology Holdings, Inc. for clinical evaluation of LB-100, one of Lixte's lead anti-cancer compounds.

6 Oct 2010

Knome announces winners of KnomeDISCOVERY Awards

Knome, Inc. today announced the winners of its inaugural KnomeDISCOVERY Awards, a program designed to spur new genetic insights into health.

6 Oct 2010

ISTO announces completion of enrollment in NuQu Phase I clinical study for discogenic back pain

ISTO Technologies, Inc., an orthobiologics company with a cell-based platform for cartilage regeneration, announced today the completion of patient enrollment in the Phase I clinical study for NuQu™, an injectable formulation of juvenile chondrocytes designed for the treatment of discogenic back pain. The study included 15 patients enrolled at two clinical sites. All patients enrolled in the trial suffered from persistent discogenic back pain and disability despite undergoing previous traditional conservative therapy.

5 Oct 2010

CPF honors three critical areas of leadership for Pulmonary Fibrosis community

The Coalition for Pulmonary Fibrosis (CPF) has announced its annual awards honoring three critical areas of leadership that impact the work of the Pulmonary Fibrosis (PF) community.

5 Oct 2010

MRI technique may help predict decline in individuals with mild cognitive impairment

Using advanced MRI and an artificial intelligence technique, researchers in Geneva, Switzerland, have identified a method that may help identify which individuals with mild cognitive impairment (MCI) will continue to decline, according to a study published online and in the December issue of Radiology.

5 Oct 2010

Archimedes publishes FPNS clinical study results in Pain journal

Archimedes Pharma US Inc. today announced publication of results from a pivotal clinical study of Fentanyl Pectin Nasal Spray (FPNS) in the treatment of breakthrough cancer pain (BTCP).

5 Oct 2010

IRIDEX announces commercial availability of extended EndoProbe laser delivery device family in Japan

IRIDEX Corporation today announced approval and commercial availability in Japan for its extended family of EndoProbe laser delivery devices. The EndoProbe is an intraocular laser delivery device used during vitreoretinal surgery for the treatment of multiple disorders including: diabetic retinopathy, retinal detachments and vitreous hemorrhage. IRIDEX distributes products in Japan through their partner, TOMEY Corporation.

5 Oct 2010

Caring.com introduces interactive Alzheimer’s resource for caregivers

Caring.com today launched Steps & Stages, the first-ever interactive guide, support system, and customized e-mail newsletter that delivers specific, stage-appropriate advice for those providing care for a loved one with Alzheimer's or another form of dementia.

5 Oct 2010

Medical Condition News

Insulin-sensitizing drugs may offer new treatments for kidney failure

Researchers discover biomarker for allergy can originate from mother

Saneron receives grant to develop safety guidelines for transplanting HUBC cells in Alzheimer's disease

Varian, IMRIS enter agreement to co-develop new MR-guided radiation therapy system for cancer

Low level of testosterone increases risk for Alzheimer's disease

Amino acid mixture increases survival in mice

ADRCs cells improve survival in acute kidney injury animal model

IDMC recommends early termination of Phase 3 intramuscular depot aripiprazole trial

Fish oil induces severe colitis and colon cancer in mice

Researchers find exposure to air pollution increases severity of asthma symptoms

Cancer cells utilize energy-rich intermediates of sugar metabolism: Research

Novel invasive surgery for children with scoliosis may eliminate need for spinal fusion

Lixte, NCI collaborate for clinical evaluation of LB-100 compound

Knome announces winners of KnomeDISCOVERY Awards

ISTO announces completion of enrollment in NuQu Phase I clinical study for discogenic back pain

CPF honors three critical areas of leadership for Pulmonary Fibrosis community

MRI technique may help predict decline in individuals with mild cognitive impairment

Archimedes publishes FPNS clinical study results in Pain journal

IRIDEX announces commercial availability of extended EndoProbe laser delivery device family in Japan

Caring.com introduces interactive Alzheimer’s resource for caregivers

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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