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Appetite hormones influence 'yo-yo' effect of slimming diets

If you want to lose the kilos you've put on over Christmas, you may be interested in knowing that the hormones related to appetite play an important role in your likelihood of regaining weight after dieting. A new study confirms that people with the highest levels of leptin and lowest levels of ghrelin are more likely to put the centimetres they lost back on again.

13 Jan 2011

Minimal invasive valve surgery provides better outcomes in older patients: Mount Sinai study

The Annals of Thoracic Surgery has just published a study conducted at Mount Sinai Medical Center of Miami Beach reporting the outcomes of minimally invasive valve surgery versus traditional median sternotomy in patients 75 years of age or older. Minimally invasive valve surgery at Mount Sinai is performed through a small, 2-inch incision on the right side of the chest, and this was compared with the same kind of valve surgery done through a breastbone splitting approach.

13 Jan 2011

Maximum Potential Group provides ABA training for parents with autistic children

Parents of children with autism often face a daunting task of paying for the prescribed hours of ABA (Applied Behavior Analysis) therapy for their children. With the rate of autism listed at 1 in every 110 children, and the average yearly cost of ABA therapy between $10,000 and $30,000, more families than ever are facing an uphill battle to pay for services.

13 Jan 2011

Health, social and economical consequences of sleep disorders: A controlled national study

"Snoring, sleep apnoea, and obesity-related respiratory difficulties are fairly common disorders that affect a large proportion of the population," according to Poul Jennum, Professor of Clinical Neurophysiology at the Center for Healthy Ageing at the University of Copenhagen Faculty of Health Sciences. He is head of the Danish Centre for Sleep Medicine, Glostrup Hospital, which treats patients from all over the country.

13 Jan 2011

MMRF, Synta collaborate for clinical development of ganetespib in multiple myeloma

The Multiple Myeloma Research Foundation (MMRF) today announced that it has entered into a joint collaboration with Synta Pharmaceuticals for the clinical development of ganetespib (formerly STA-9090) in patients with multiple myeloma.

13 Jan 2011

Researchers launch estrogen therapy trial to study depression, cardiovascular illness in women

Researchers at the University of North Carolina at Chapel Hill have launched a new clinical trial to determine if estrogen replacement therapy may help prevent depression and cardiovascular illness in women between the ages of 45 and 55.

13 Jan 2011

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

Research conducted by Iaroslav Savtchouk, a graduate student, and S. June Liu, PhD, Associate Professor of Cell Biology and Anatomy at LSU Health Sciences Center New Orleans, has shown that a single exposure to acute stress affected information processing in the cerebellum - the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation.

13 Jan 2011

TKM-PLK1 drug may offer hope for patients with advanced solid tumor cancers

A new investigational drug designed to stop cancer cells from reproducing may offer hope for patients with advanced solid tumor cancers. Clinical trials of TKM-PLK1 for qualified patients are now open at the Virginia G. Piper Cancer Center at Scottsdale Healthcare.

13 Jan 2011

IRB approves Revolutions Medical's MRI software tools

Revolutions Medical Corporation is happy to report that it has received notice that Investigational Review Board approval has been granted this month to the Philadelphia College of Osteopathic Medicine for the research project application titled 'Characterization of Intracranial Hemorrhages by Color MRI Automatic Segmentation,' by Dr. H. Keith Brown and his collaborators.

13 Jan 2011

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Beth Israel Deaconess Medical Center cancer geneticist Pier Paolo Pandolfi, MD, PhD, is the recipient of the 2011 Pezcoller Foundation-AACR (American Association of Cancer Research) International Award for Cancer Research.

13 Jan 2011

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

Pfizer Inc. announced today that it has initiated the rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for crizotinib (PF-02341066), an oral first-in-class anaplastic lymphoma kinase (ALK) inhibitor for the treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumors are ALK-positive. Pfizer expects to complete the submission in the first half of 2011.

13 Jan 2011

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

New research has found one of the smallest entities in the human genome, micro-RNA, could increase the risk of limb amputation in diabetic patients who have poor blood flow.

13 Jan 2011

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

Eli Lilly and Company announced the U.S. Food and Drug Administration (FDA) Gastrointestinal Drugs Advisory Committee voted today to recommend non-approval of liprotamase, a non-porcine pancreatic enzyme replacement therapy (PERT), currently under FDA review for the treatment of exocrine pancreatic insufficiency (EPI).

13 Jan 2011

New discovery has brought dream of transforming measles virus against cancer

When most people in the developed world think of measles, what comes to mind is only a dim memory of a vaccination at a pediatrician's office. But while childhood vaccination has virtually eliminated measles from North America and much of Europe, researchers remain interested in the virus.

13 Jan 2011

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Some disorders of the brain are obvious - the massive death of brain cells after a stroke, the explosion in the growth of cells that marks a tumor. Other disorders, such as autism, schizophrenia and mental retardation show no physical signs of damage and are believed to be caused by problems in how brain cells communicate with one another.

13 Jan 2011

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Though the cause of Alzheimer's disease still is unknown, recent studies have implicated three proteins strongly in its onset. New research from the University of Alabama at Birmingham, the Gladstone Institutes and the Baylor College of Medicine indicates that interactions between those three proteins might lead to brain dysfunction and AD in a mouse model of the disease.

13 Jan 2011

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

13 Jan 2011

Obesity in children today may contribute to 2-5 year decline in life expectancy

For the first time in history, the next generation will not live longer, or even as long, as their parents. "Diseases such as Type II diabetes, high blood pressure, heart conditions and joint deterioration - what were once considered 'adult' diseases - are regularly being diagnosed in children, due to the prevalence of obesity," said Jessica Bartfield, MD, internal medicine and medical weight-loss specialist at Gottlieb Memorial Hospital, part of the Loyola University Health System.

13 Jan 2011

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

A team of researchers from the Peninsula College of Medicine and Dentistry are part of a wider group of researchers from leading institutions that will implement a -4.7m Policy Research Unit dedicated to achieving early cancer screening and diagnosis. The funding is provided over five years by the Department of Health and will be led by Queen Mary, University of London.

13 Jan 2011

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

MedImmune, the global biologics unit of AstraZeneca PLC and Micromet, today announced the initiation of a Phase 1 trial of MEDI-565 in patients with advanced gastrointestinal cancers. MEDI-565 is a BiTE antibody designed to direct a patient's T cells, the body's most potent killer cells, against cancer cells that express carcinoembryonic antigen.

13 Jan 2011

Medical Condition News

Appetite hormones influence 'yo-yo' effect of slimming diets

Minimal invasive valve surgery provides better outcomes in older patients: Mount Sinai study

Maximum Potential Group provides ABA training for parents with autistic children

Health, social and economical consequences of sleep disorders: A controlled national study

MMRF, Synta collaborate for clinical development of ganetespib in multiple myeloma

Researchers launch estrogen therapy trial to study depression, cardiovascular illness in women

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

TKM-PLK1 drug may offer hope for patients with advanced solid tumor cancers

IRB approves Revolutions Medical's MRI software tools

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

New discovery has brought dream of transforming measles virus against cancer

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

Obesity in children today may contribute to 2-5 year decline in life expectancy

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

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