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Scientists identify new strategy for treating movement disorders

Scientists at the Gladstone Institute of Neurological Disease and Stanford University have shown how key circuits in the brain control movement. The research, published in the journal Nature not only establishes the function of these circuits, but offers promise for treating movement related disorders, such as Parkinson's disease.

8 Jul 2010

FDA issues formal response to Nephros' 510(k) application for hemodiafiltration system

Nephros, Inc., a medical device company developing and marketing filtration products for therapeutic applications, infection control, and water purification, today reported that the U.S. Food and Drug Administration has issued a formal response to the company's 510(k) application.

8 Jul 2010

Bowel cancer screening test may be less likely to spot cancerous changes in summer: Study

A new study suggests that the test used in the Italian national bowel cancer screening programme may be less likely to spot cancerous changes in summer than it is in winter.

8 Jul 2010

Common glucose test accurately predicts Type II adult-onset diabetes, study finds

A common test to diagnose gestational diabetes -- a temporary condition which can harm both mother and child if left untreated -- also has predictive power for Type II adult-onset diabetes, a new Tel Aviv University study finds.

8 Jul 2010

NOXXON to commence multiple ascending dose study of MCP-1 targeting anti-inflammatory Spiegelmer NOX-E36

NOXXON Pharma AG announced today that it has permission to commence a multiple ascending dose study of its Monocyte Chemoattractant Protein-1 (MCP-1) targeting anti-inflammatory Spiegelmer®, NOX-E36. NOXXON plans to develop NOX-E36 for the treatment of diabetic nephropathy and other diabetes related complications.

7 Jul 2010

ISCO and Sankara Nethralaya collaborate to develop "CytoCor" stem cell-derived corneal tissue

International Stem Cell Corporation and Sankara Nethralaya, announced today commencement of a collaboration to develop ISCO's "CytoCor™" stem cell-derived corneal tissue. The goal is to use CytoCor to treat corneal blindness and vision impairment. "This is one more step in ISCO's stated plan of building its portfolio of therapeutic agents through strategic alliances throughout the world," said Chairman, Ken Aldrich.

7 Jul 2010

Uptake Medical completes Series B financing led by Maverick Capital

Uptake Medical, a privately held interventional pulmonology company, announced today that it has concluded its Series B financing from an investment group led by Maverick Capital, a new investor. The company plans to use this capital to obtain the CE mark and introduce its unique proprietary Bronchoscopic Thermal Vapor Ablation (BTVA) technology outside of the U.S. The company also has begun its approval cycle with the FDA in the U.S.

7 Jul 2010

Winston submits NDA for CIVANEX to U.S. FDA

Winston Laboratories, Inc., a wholly-owned subsidiary of Winston Pharmaceuticals, Inc., a pharmaceutical company focused on developing and commercializing novel pain management therapies, announced that it has submitted a new drug application (NDA) with the U.S. Food and Drug Administration (FDA) for approval to market its civamide (zucapsaicin) 0.075% cream, CIVANEX®, for the treatment of signs and symptoms of osteoarthritis of the knee.

7 Jul 2010

FDA grants orphan drug designation for Synageva BioPharma's SBC-102

Synageva BioPharma Corp., a privately held biopharmaceutical company, announced that the U.S. Food and Drug Administration has granted orphan drug designation for SBC-102, the Company's enzyme replacement therapy in development to treat Lysosomal Acid Lipase Deficiency, also known as Wolman Disease and Cholesteryl Ester Storage Disease, a condition for which there is currently no approved treatment.

7 Jul 2010

Use of NSAIDs do not increase risk of heart attack in elderly patients: Study

Commonly used painkillers like ibuprofen do not increase the risk of heart attack in the elderly population, according to a new study. Researchers found that the use of these drugs - also called non-steroidal anti-inflammatory drugs - was also associated with a lower risk of death although they are not sure why.

7 Jul 2010

Scientists identify potential disease genes in humans and mice

An international consortium of scientists of Helmholtz Zentrum München and the University of Toronto has identified previously unknown potential disease genes in humans and mice. Genes on the X chromosome, which regulate embryonic development, are the focus of the current publication in the renowned journal Genome Research. Men have only one X chromosome, and therefore mutations on this chromosome disproportionately affect males, frequently leading to serious diseases such as hemophilia, muscular dystrophy and mental retardation.

7 Jul 2010

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today it has initiated dosing in a Phase I human clinical study with ALN-TTR01. The study is aimed at evaluating the safety and tolerability of ALN-TTR01 in patients with transthyretin -mediated amyloidosis, and is also designed to provide preliminary data on human proof of concept based on measurements of TTR serum levels.

7 Jul 2010

Nile completes dosing in CD-NP Phase II study for acute decompensated heart failure

Nile Therapeutics, Inc., a biopharmaceutical company focused on the development of novel therapeutics for cardiovascular disease, today announced that it has completed the dosing of the last patient in NIL-CDNP-CT005, an open-label, single-blind, placebo-controlled Phase II study of CD-NP in patients with acute decompensated heart failure, or ADHF. The study was designed to provide additional information on the safety and tolerability of CD-NP when infused for up to 72 hours in patients with ADHF and mild to moderate renal insufficiency.

7 Jul 2010

Researchers to discuss connection between brown fat and obesity

Researchers from all over the world will meet at Stockholm University this weekend, July 10 and 11, to discuss for the first time the connection in adult humans between brown fat and the risk of becoming obese.

7 Jul 2010

Insights into complex interrelationships between heart and kidneys

Research is yielding new understanding of the interactions between the heart and the kidneys—particularly the cardiorenal syndrome, in which failure of either organ can lead to failure of the other. Recent insights into the complex interrelationships between the heart and kidneys are presented in a special symposium section of the July issue of The American Journal of Medical Sciences (AJMS), official journal of the Southern Society for Clinical Investigation.

7 Jul 2010

CME announces conference on mind-body connection in psychiatric disorders

CME LLC announces Treating the Whole Patient: The Mind-Body Connection in Psychiatric Disorders, a one-day educational conference for professionals to be held on August 14, 2010, at The Island Hotel in Newport Beach, California. Leading mental health experts Rakesh Jain, MD, MPH, Jon W. Draud, MD, MS, Vladimir Maletic, MD, and Charles Raison, MD will review the most recent developments concerning the relationship between mental and physical health conditions and explore the concept of Wellness.

7 Jul 2010

Study finds link between early nutrition and arthritis in people and moose

It's seen as a sign of getting old, but scientists have discovered that arthritis is not just a human problem as a study lasting 50 years reveals how moose suffer from an identical form of the condition. The research, published in Ecology Letters, also casts new light on how malnutrition early in life can lead to the disorder in both moose and humans.

7 Jul 2010

MJFF announces $1.1M for projects to develop biomarker candidates for PD

The Michael J. Fox Foundation for Parkinson's Research today announced nearly $1.1 million for projects aimed at advancing the development of leading biomarker candidates for Parkinson's disease. The discovery and validation of biomarkers is of critical importance to increasing the speed and efficiency of PD therapeutic development, allowing scientists and clinicians to more accurately identify appropriate subjects for clinical studies, measure disease progression and monitor treatment effects in clinical trials.

7 Jul 2010

LBP related beliefs, behaviors affect disability more than pain intensity: Study

Approximately 10% of low back pain (LBP) sufferers experience persistent pain and significant disability. In a study published in the August issue of Pain, a group of Australian researchers investigating the relevance of health literacy in patients with chronic lower back pain (CLBP) found that LBP-related beliefs and behaviors affect a person's disability more than pain intensity or a standard measure of functional health literacy.

7 Jul 2010

Teenage Cancer Trust: 26 % of young people plan to get sunburnt on purpose

More than a quarter of teenagers will get sunburnt on purpose this summer in the belief that they will ultimately get a suntan, a survey has found. The Teenage Cancer Trust discovered that 26 per cent of young people, aged 13 to 19, plan to get sunburnt on purpose this year.

7 Jul 2010

Medical Condition News

Scientists identify new strategy for treating movement disorders

FDA issues formal response to Nephros' 510(k) application for hemodiafiltration system

Bowel cancer screening test may be less likely to spot cancerous changes in summer: Study

Common glucose test accurately predicts Type II adult-onset diabetes, study finds

NOXXON to commence multiple ascending dose study of MCP-1 targeting anti-inflammatory Spiegelmer NOX-E36

ISCO and Sankara Nethralaya collaborate to develop "CytoCor" stem cell-derived corneal tissue

Uptake Medical completes Series B financing led by Maverick Capital

Winston submits NDA for CIVANEX to U.S. FDA

FDA grants orphan drug designation for Synageva BioPharma's SBC-102

Use of NSAIDs do not increase risk of heart attack in elderly patients: Study

Scientists identify potential disease genes in humans and mice

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Nile completes dosing in CD-NP Phase II study for acute decompensated heart failure

Researchers to discuss connection between brown fat and obesity

Insights into complex interrelationships between heart and kidneys

CME announces conference on mind-body connection in psychiatric disorders

Study finds link between early nutrition and arthritis in people and moose

MJFF announces $1.1M for projects to develop biomarker candidates for PD

LBP related beliefs, behaviors affect disability more than pain intensity: Study

Teenage Cancer Trust: 26 % of young people plan to get sunburnt on purpose

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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