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IRX Therapeutics raises $8M to further develop pipeline of cancer vaccine candidates

IRX Therapeutics, a developer of novel immunomodulators to treat cancer and viral diseases, today announced that it has raised $8 million through a note offering to existing shareholders. The new funding will be used to further develop its pipeline of cancer vaccine candidates, including its lead product, IRX-2. IRX Therapeutics has now raised a total of more than $80 million in private financing.

17 Jun 2010

FDA approves clinical testing of SanBio's SB623 for stroke recovery

SanBio Inc. announced today that the United States Food and Drug Administration (FDA) has approved the clinical testing of their SB623 regenerative medicine product in patients suffering from disability caused by cerebral stroke. SB623 is derived from bone marrow stromal cells (MSCs) isolated from healthy adult donors.

17 Jun 2010

Alcohol consumption associated with reduced risk of developing several arthritic conditions: Study

Alcohol consumption is associated with a significantly reduced risk of developing several arthritic conditions including Rheumatoid Arthritis, Osteoarthritis, reactive arthritis, psoriatic arthritis and spondylarthropathy, according to results of a new study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

17 Jun 2010

AGA Medical commences enrollment in AMPLATZER Cardiac Plug clinical trial

AGA Medical Holdings, Inc. today announced first patient enrollment in the feasibility phase of the prospective, multicenter, randomized AMPLATZER® Cardiac Plug clinical trial. Dr. William Nicholson, an interventional cardiologist and structural heart specialist at York Hospital in Pennsylvania, enrolled the first patient.

16 Jun 2010

Fortis International Oncology Centre equipped with Varian's advanced radiotherapy equipment

The first in a planned series of new radiotherapy centers aimed at improving access to advanced treatments for millions of Indian cancer patients has been officially opened in Noida. Fortis International Oncology Centre, a joint initiative between International Oncology and Fortis Healthcare, is equipped with advanced radiotherapy equipment and software from Varian Medical Systems.

16 Jun 2010

USPTO issues patent covering Probuphine for opiate addiction

Titan Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office (USPTO) has issued patent number 7,736,665 covering Probuphine for the treatment of opiate addiction.

16 Jun 2010

Dietary guideline on sodium puts Americans at risk

The Dietary Guidelines Advisory Committee (DGAC) of the U.S. Department of Health and Human Services and the U.S. Department of Agriculture may increase health risks, including obesity, by ignoring sound science as they announce recommendations to reduce sodium consumption to 1,500 mg per day, says the Salt Institute.

16 Jun 2010

Management of cardiovascular risk associated with insulin resistance, diabetes, and the metabolic syndrome

Adi Mehta, MD stresses the growing severity of the metabolic syndrome in the May 2010 edition of Postgraduate Medicine. Metabolic syndrome often leads to cardiovascular disease (CVD) because of its key components: diabetes, dyslipidemia, and hypertension. With obesity maintaining its status as a huge problem worldwide, physicians must act as soon as possible when they recognize metabolic syndrome or any of its components.

16 Jun 2010

New perspectives in type 2 diabetes, cardiovascular risk, and treatment goals

An article published in the May 2010 issue of Postgraduate Medicine highlights the seriousness of cardiovascular disease (CVD) in patients with type 2 diabetes. Cardiovascular disease is the cause of death in > 65% of patients with diabetes, and when complicated by the presence of obesity, the lifetime risk of developing CVD increases to 90%. The inherent problem is that many of the antihyperglycemic medications used to combat high glycated hemoglobin are associated with weight gain and/or hypoglycemia, which negatively affect CVD.

16 Jun 2010

A review of the response to oral anti-diabetes agents in patients with type 2 diabetes

Patients with type 2 diabetes show a progressive decline in glycemic control and receive antidiabetic therapy in order to reach the target glycated hemoglobin level of < 7% set by the American Diabetes Association and the European Association for the Study of Diabetes. An article published in the May 2010 issue of Postgraduate Medicine reviews the effectiveness of oral antidiabetes (OAD) agents in maintaining glycemic control in patients with type 2 diabetes.

16 Jun 2010

How to obtain appropriate type 2 diabetes control in the first 180 days of treatment initiation

Type 2 diabetes is characterized by unsatisfactory levels of glycated hemoglobin (HbA1c) for extended periods. An article published in the May 2010 edition of Postgraduate Medicine reports a proposal to shorten the total time spent with uncontrolled hyperglycemia by minimizing the number of steps along the treatment-intensification ladder. In doing so, patients would decrease their exposure to hyperglycemia and potentially improve long-term outcomes.

16 Jun 2010

Meningococcal disease in infants: A potentially difficult and serious diagnosis

An article published in the May 2010 edition of Postgraduate Medicine documents a case study where a previously healthy, 15-week-old male infant was misdiagnosed and died of meningococcal disease. Initially the patient showed signs of the common cold and was treated as such, but symptoms worsened and he was admitted to the hospital emergency department.

16 Jun 2010

Relypsa commences enrollment for RLY5016 Phase 2 study in heart failure patients with chronic kidney disease

Relypsa, Inc., today announced the initiation of patient enrollment in a Phase 2, open-label titration clinical study of the company's lead drug candidate, RLY5016, in heart failure patients with chronic kidney disease. RLY5016 is a novel non-absorbed oral potassium binder intended to prevent and treat hyperkalemia, a serious condition characterized by elevated serum potassium levels.

16 Jun 2010

OXiGENE completes enrollment in ZYBRESTAT Phase 2 FALCON trial for NSCLC

OXiGENE, Inc., a clinical-stage, biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases, announced today that it has completed its targeted enrollment of 60 patients in the FALCON trial, a randomized, controlled Phase 2 study of ZYBRESTAT™ in patients with non-squamous non-small cell lung cancer (NSCLC).

16 Jun 2010

Phase 3 U.S. registration study of LODOTRA shows improvement in patients with RA

Horizon Pharma, Inc., announced today that data from the Phase 3 U.S. registration study of LODOTRA, a circadian cytokine modulator and novel modified-release, low-dose prednisone tablet, showed a statistically significant improvement in American College of Rheumatology response criteria in patients with rheumatoid arthritis.

16 Jun 2010

RG7204 holds promise for metastatic melanoma with V600E BRAF mutation

Preclinical findings recently published in Cancer Research, a journal of the American Association for Cancer Research, showed RG7204 (PLX4032) inhibited proliferation of tumor cell lines that expressed V600E-BRAF, a mutation found in several human cancers, including melanoma.

16 Jun 2010

CAMFT listed in 2010 Associations Advance America Honor Roll

The California Association of Marriage and Family Therapists has been named to the 2010 Associations Advance America Honor Roll, a national awards competition sponsored by the American Society of Association Executives & The Center for Association Leadership, Washington, D.C.

16 Jun 2010

Stress-related psychiatric disorders more common among women: Study

There may be a biological reason why depression and other stress-related psychiatric disorders are more common among women compared to men. Studying stress signaling systems in animal brains, neuroscience researchers found that females are more sensitive to low levels of an important stress hormone and less able to adapt to high levels than males.

16 Jun 2010

MainStreet Monitoring Devices announces cause marketing partnership with Special Olympics Massachusetts

MainStreet Monitoring Devices, Inc., an innovator of superior personal safety, telemedicine and wireless health solutions to advance the care and protection of children and seniors, today announces its marketing partnership with Special Olympics Massachusetts on the eve of the 2010 Summer Games. MainStreet MD will donate a portion of its proceeds in support of more than 2200 Special Olympics athletes expected to compete in the Summer Games scheduled June 18-20, at Harvard University.

16 Jun 2010

Phase IIb EMBLEM study demonstrates clinical efficacy of epratuzumab in patients with SLE

UCB and Immunomedics Inc. announced new lupus drug candidate, epratuzumab, provided a significant reduction in disease activity in patients with moderate to severe active systemic lupus erythematosus (SLE). Data presented at the European League Against Rheumatism (EULAR) meeting in Rome from the phase IIb study, EMBLEM™, showed the clinical efficacy of epratuzumab in patients with SLE.

16 Jun 2010

Medical Condition News

IRX Therapeutics raises $8M to further develop pipeline of cancer vaccine candidates

FDA approves clinical testing of SanBio's SB623 for stroke recovery

Alcohol consumption associated with reduced risk of developing several arthritic conditions: Study

AGA Medical commences enrollment in AMPLATZER Cardiac Plug clinical trial

Fortis International Oncology Centre equipped with Varian's advanced radiotherapy equipment

USPTO issues patent covering Probuphine for opiate addiction

Dietary guideline on sodium puts Americans at risk

Management of cardiovascular risk associated with insulin resistance, diabetes, and the metabolic syndrome

New perspectives in type 2 diabetes, cardiovascular risk, and treatment goals

A review of the response to oral anti-diabetes agents in patients with type 2 diabetes

How to obtain appropriate type 2 diabetes control in the first 180 days of treatment initiation

Meningococcal disease in infants: A potentially difficult and serious diagnosis

Relypsa commences enrollment for RLY5016 Phase 2 study in heart failure patients with chronic kidney disease

OXiGENE completes enrollment in ZYBRESTAT Phase 2 FALCON trial for NSCLC

Phase 3 U.S. registration study of LODOTRA shows improvement in patients with RA

RG7204 holds promise for metastatic melanoma with V600E BRAF mutation

CAMFT listed in 2010 Associations Advance America Honor Roll

Stress-related psychiatric disorders more common among women: Study

MainStreet Monitoring Devices announces cause marketing partnership with Special Olympics Massachusetts

Phase IIb EMBLEM study demonstrates clinical efficacy of epratuzumab in patients with SLE

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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