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Nuon Therapeutics NU1618 phase 2a study in hyperuricemia meets primary endpoint

Nuon Therapeutics, Inc., a privately held, clinical stage biopharmaceutical company, announced that a phase 2a study of NU1618, the company's lead program, met its primary endpoint of reduction in serum uric acid (sUA) levels in patients with hyperuricemia.

16 Jun 2010

AVEO granted patents for tests to identify cancer patients likely to respond to tivozanib

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced the issuance of U.S. Patent Nos. 7,615,353, which issued in November 2009, and 7,736,861, which issued yesterday.

16 Jun 2010

Report on treatment trends in systemic lupus erythematosus

BioTrends is pleased to announce the upcoming publication of a new syndicated report, TreatmentTrends®: Systemic Lupus Erythematosus (SLE). This report will provide a comprehensive market overview of current and future treatment trends in SLE based on a primary research study fielded with 102 rheumatologists in the U.S. during the first week in June.

16 Jun 2010

Identification of key player in signaling pathway offers hope for new targeted melanoma therapies

Identification of a key player in a signaling pathway involved in the development of melanoma - the deadliest form of skin cancer - may offer hope for new targeted melanoma therapies.

16 Jun 2010

UNC researchers study why surgery happens less often in blacks with lung cancer

A new study led by UNC researchers that looks at newly diagnosed lung cancer patients and follows them from diagnosis forward is one of the first to give reasons why patients don't go to lung surgery and why surgery happens less often in blacks.

16 Jun 2010

Abbott, Neurocrine enter collaboration to develop, commercialize elagolix for endometriosis-related pain

Abbott and Neurocrine Biosciences, Inc. today announced that they have entered into a collaboration agreement to develop and commercialize elagolix for the treatment of endometriosis-related pain. Elagolix is a novel, first-in-class oral gonadotropin-releasing hormone (GnRH) antagonist, which has recently completed a phase IIb study in endometriosis. In addition to endometriosis, elagolix will be evaluated for the treatment of uterine fibroids.

16 Jun 2010

Physicians play stronger role in ensuring asthma patients don't waver in taking drugs: Researchers

Armed with the right information, physicians can play a stronger role in ensuring asthma patients don't waver in taking drugs proven to prevent asthma attacks, according to researchers at Henry Ford Hospital in Detroit.

16 Jun 2010

Independent SMB recommends continuance of Allovectin-7 Phase 3 trial for metastatic melanoma

Vical Incorporated today announced that an independent Safety Monitoring Board (SMB) for the company's Phase 3 trial of Allovectin-7® in patients with metastatic melanoma has completed the trial's fourth scheduled safety analysis and recommended that the trial continue per the protocol.

16 Jun 2010

Molecular imaging fusion with CT anatomy results in precise localization of parathyroid lesions: Research

SNM's 2010 Image of the Year illustrates the potential of hybrid molecular imaging to provide precise information about the location and function of a condition known as "hyperparathyroidism." Researchers selected this image from more than 1,500 studies presented over the course of four days during SNM's 57th Annual Meeting in Salt Lake City.

16 Jun 2010

3 new genes in genetic research of suicidal behaviour

Three genes that have barely been studied to date have now provided fresh knowledge about patients with suicidal backgrounds. This is the result of a study by a team of Spanish researchers at Mount Sinai Hospital and Columbia University in the City of New York (United States), which found that several mutations are involved. This finding could help to develop future genetic tests to identify predisposition to suicide, without ignoring the importance of social and cultural factors.

16 Jun 2010

Many Huntington's disease patients suffer from weight loss, sleeping problems

An aggregating protein causes many of the symptoms of Huntington's disease, an incurable and frequently fatal brain disorder. Mosaic winner Ahmad Aziz discovered that the abnormal protein also aggregates in the hypothalamus, the part of the brain that regulates the autonomic nervous system and the endocrine system.

16 Jun 2010

Prevalence of GID in PD patients has impact on clinical and societal outcomes: Study

New data from a retrospective cohort study showed that up to three quarters of patients with Parkinson's disease developed gastrointestinal disorders that can have a substantial adverse effect on major PD-related clinical and health economic outcomes. These data were presented at the 14th International Congress of Parkinson's Disease and Movement Disorders in Buenos Aires, Argentina (June 13-17, 2010).

16 Jun 2010

NTI to grant $2.8 million to promising trauma studies

The National Trauma Institute, a non-profit organization dedicated to funding trauma research in the United States, will grant $2.8 million to promising trauma studies. In its second national request for proposals, NTI seeks rigorous clinical studies, especially those addressing hemorrhage, intensive care, trauma systems or pre-hospital care.

16 Jun 2010

New online smoking-cessation study launched

Fred Hutchinson Cancer Research Center announced today that it is launching a new online study to help people quit smoking. The study, called WebQuit, is enrolling adult smokers nationwide. Participation is free to eligible individuals.

16 Jun 2010

Norgine to develop and commercialize Tranzyme's ulimorelin ghrelin agonist

Tranzyme Pharma, a clinical-stage biopharmaceutical company, and Norgine B.V., a European specialty pharmaceutical company, announced today that they have entered into a licensing agreement that provides Norgine with the exclusive rights to develop and commercialize Tranzyme's novel ghrelin agonist, ulimorelin (TZP-101), in Europe, Australia, New Zealand, the Middle East, South Africa and North Africa. Ulimorelin is entering Phase 3 development for the treatment of gastrointestinal dysmotility conditions in acute care settings.

16 Jun 2010

Dutch researcher investigates causes and consequences of insomnia

The brains of older adults with chronic sleep problems look different from those of adults who have enjoyed enough sleep. Yet the older adults function well despite their lack of sleep. They switch to a continuous form of mild stress, as a result of which they sometimes even perform better than contemporaries who enjoy a good night's sleep says Dutch researcher Ellemarije Altena.

16 Jun 2010

Study demonstrates mechanism behind hijacking of TNF controlled response to tumours

Cancer Research UK scientists have discovered how two genes can 'hijack' control of part of the body's defences against cancer, helping them grow and spread.

16 Jun 2010

Study examines survival rates of CF patients with MRSA

A team of researchers led by Elliott Dasenbrook, MD, MHS, Assistant Professor of Medicine and Pediatrics at Case Western Reserve University School of Medicine and Associate Director of the Adult Cystic Fibrosis Program at University Hospitals Case Medical Center's Rainbow Babies & Children's Hospital today published the findings from a major study about cystic fibrosis survival rates in the June 16 issue of JAMA.

16 Jun 2010

Interventions are needed to make people exercise after cardiac event

Researchers from the Frances Payne Bolton School of Nursing at Case Western Reserve University found that one year after 248 individuals completed a 12-week cardiac rehabilitation program following a heart attack, bypass surgery or angioplasty, only 37% exercised three times a week to keep their hearts healthy.

16 Jun 2010

Diabetes associated with increased risk of cancer

A new consensus statement of experts assembled by the American Diabetes Association and the American Cancer Society reviews emerging evidence that suggests cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. The new report reviews the state of science concerning the association between diabetes and cancer incidence/prognosis; risk factors common to both diseases; possible biologic links between diabetes and cancer risk; and whether diabetes treatments influence the risk of cancer or cancer prognosis.

16 Jun 2010

Medical Condition News

Nuon Therapeutics NU1618 phase 2a study in hyperuricemia meets primary endpoint

AVEO granted patents for tests to identify cancer patients likely to respond to tivozanib

Report on treatment trends in systemic lupus erythematosus

Identification of key player in signaling pathway offers hope for new targeted melanoma therapies

UNC researchers study why surgery happens less often in blacks with lung cancer

Abbott, Neurocrine enter collaboration to develop, commercialize elagolix for endometriosis-related pain

Physicians play stronger role in ensuring asthma patients don't waver in taking drugs: Researchers

Independent SMB recommends continuance of Allovectin-7 Phase 3 trial for metastatic melanoma

Molecular imaging fusion with CT anatomy results in precise localization of parathyroid lesions: Research

3 new genes in genetic research of suicidal behaviour

Many Huntington's disease patients suffer from weight loss, sleeping problems

Prevalence of GID in PD patients has impact on clinical and societal outcomes: Study

NTI to grant $2.8 million to promising trauma studies

New online smoking-cessation study launched

Norgine to develop and commercialize Tranzyme's ulimorelin ghrelin agonist

Dutch researcher investigates causes and consequences of insomnia

Study demonstrates mechanism behind hijacking of TNF controlled response to tumours

Study examines survival rates of CF patients with MRSA

Interventions are needed to make people exercise after cardiac event

Diabetes associated with increased risk of cancer

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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