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New molecular map offers insights into human physiology and disease

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules measured in blood, urine and saliva samples from 391 volunteers.

11 Sep 2024

Innovative method unlocks potential for drugging undruggable GTPases

Drugs for the K-Ras oncogene inspire an approach for targeting the GTPases, a family of enzymes whose dysfunction can lead to Parkinson's and many other diseases.

11 Sep 2024

Research aims to improve interstitial lung disease prognosis with new imaging agent

Researchers at the University of Exeter and clinical radiopharmaceutical company Serac Healthcare Ltd are researching a new molecular imaging marker which could help to detect disease progression sooner.

11 Sep 2024

People with dementia may be at higher risk of having suicidal thoughts

People with dementia are more likely to have suicidal thoughts but are not necessarily more likely to attempt or die by suicide than the general population, finds a new study led by UCL researchers.

11 Sep 2024

Heatwaves linked to increased seizures in epilepsy patients

Heatwaves can worsen abnormal excitability of the brain in people with epilepsy, finds a new small-scale patient study by clinical scientists at UCL.

11 Sep 2024

C1QL1 protein identified as key to myelin replacement

The neurons of the brain are protected by an insulating layer called myelin. In certain diseases like multiple sclerosis, this protective layer is damaged and lost, leading to death of neurons and disability.

11 Sep 2024

Throat problems linked to decreased baroreflex sensitivity

Patients with throat problems were less able to regulate their blood pressure in a new study led by the University of Southampton.

11 Sep 2024

COVID-19 mRNA vaccine linked to myocardial scarring in adolescents and young adults

The study investigates COVID-19 vaccine-related myocarditis in adolescents, revealing clinical characteristics and risks of myocardial injury in young adults.

11 Sep 2024

PDX engraftment predicts high recurrence and poor survival in triple-negative breast cancer

Researchers examine the association between patient-derived xenograft with recurrence and survival rates in triple negative breast cancer patients.

11 Sep 2024

New study links gut bacteria to thiamine's role in reducing fatigue in IBD patients

Researchers explore the frequency of symptoms like chronic fatigue in IBD in relation to specific bacteria in the human gut.

11 Sep 2024

Obesity increases risk of contracting COVID-19 after exposure to SARS-CoV-2

Researchers reveal that obesity also increases the risk of contracting COVID-19 following exposure to SARS-CoV-2.

11 Sep 2024

A promising new therapeutic target for MASLD identified

Using a novel stem cell platform, a team of the Medical University of South Carolina researchers has identified a pathway that could be targeted by drugs to reduce fat accumulation in patients with a common form of fatty liver disease known as metabolic dysfunction-associated steatotic liver disease, or MASLD.

11 Sep 2024

New study explores the potential of hormone therapy for opioid recovery

In the midst of America's growing opioid crisis, a much healthier alternative to long-term pain management is emerging -; one affectionately known as "the cuddle hormone," or oxytocin.

11 Sep 2024

TAAR1 gene: A new key to mental health

In the complex landscape of mental health research, a new peer-reviewed Viewpoint review sheds light on an underexplored genetic player: the trace amine-associated receptor 1 (TAAR1). Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis suggests that mutations in the TAAR1 gene may be a crucial piece of the puzzle in understanding and treating neuropsychiatric disorders.

11 Sep 2024

New insights into the genetics of schizophrenia

In the complex landscape of mental health research, a new peer-reviewed viewpoint offers a critical examination of how genes and environment conspire to influence schizophrenia risk. Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis by researchers Natassia Robinson and Sarah E. Bergen from Karolinska Institutet in Stockholm, Sweden, brings together cutting-edge findings from genetics and epidemiology.

11 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

NIH funds study to assess wearable sleep trackers for Alzheimer's prediction

The National Institutes of Health has awarded Joyita Dutta, professor of biomedical engineering at the University of Massachusetts Amherst, $3.9 million over five years to study if wearable sleep trackers can predict blood biomarkers of Alzheimer's disease in at-risk individuals.

11 Sep 2024

New guidelines for the evaluation and management of chronic constipation

The American Society of Colon and Rectal Surgeons (ASCRS) has issued updated guidelines, published in Diseases of the Colon & Rectum, about how to evaluate and manage chronic constipation. The journal is published in the Lippincott portfolio by Wolters Kluwer.

11 Sep 2024

Air pollution raises lung cancer risk for women

Recent air pollution exposure in the form of particles smaller than 2.5 micrometers (PM2.5) exposure may significantly impact lung cancer in women who have never smoked, with notable differences in stage IV diagnoses among EGFR+ patients, according to research presented today at the International Association for the Study of Lung Cancer (IASLC) 2024 World Conference on Lung Cancer.

11 Sep 2024

Fibrous scars drive glioblastoma recurrence

A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, surgery, and immunotherapy.

11 Sep 2024