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Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

Can an online lifestyle plan keep your brain sharp? Research says yes

"Maintain Your Brain" study shows how a tailored online program can improve cognition and lower dementia risk—discover how simple lifestyle changes could protect your brain as you age.

29 Jan 2025

Study identifies potential gain of function mutation in retinoblastoma

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation."

29 Jan 2025

Researchers propose personalized probiotic therapies for inflammatory diseases

A new approach to treating inflammatory diseases through personalized probiotic therapies – also known as precision medicine – has been proposed by researchers at the University of Surrey.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Exploring the interaction between cell death and cellular senescence in cancer

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

29 Jan 2025

Study aims to explore structural alterations in the brains of people with bipolar disorder

A new study, led by USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), will explore structural alterations in the brains of people with bipolar disorder (BD), a chronic mental illness with one of the highest rates of attempted suicide - and for which no biological tools currently exist to guide diagnosis or treatment.

29 Jan 2025

Chemotherapy linked to persistent nerve pain in 4 in 10 cancer patients

Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published in the open access journal Regional Anesthesia & Pain Medicine.

29 Jan 2025

Sports betting is coming to Missouri. A fund to help prevent problem gambling will follow.

Listen as senior producer Zach Dyer reports on the public health concerns over online sports betting and a fund in Missouri that might help with addiction treatment and prevention.

29 Jan 2025

Potato consumption not linked to heart disease or hypertension

The analysis indicates that while potatoes don't raise heart disease risk, fried varieties may contribute to higher hypertension risk with regular consumption.

29 Jan 2025

Prolonged REM sleep latency linked to Alzheimer’s disease biomarkers

Research indicates longer REM latency is associated with higher Alzheimer's biomarkers, pointing to its potential as an early indicator of neurodegeneration.

29 Jan 2025

Swedish study reveals gaps in pain management for preterm infants

Research on pain in preterm infants shows frequent painful procedures and inadequate pain management, emphasizing the need for better assessment strategies.

29 Jan 2025

Calorie labels on menus harm people with eating disorders

Calorie labels on restaurant menus are negatively impacting people with eating disorders, according to a new study published today in the BMJ Public Health.

29 Jan 2025

Discovery could contribute to the development of new drugs for transthyretin amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

AI technology uncovers genetic factors and treatment options for Parkinson's

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

28 Jan 2025

Groundbreaking research reveals key gut cells involved in food tolerance

With every bite of food we take, our intestinal immune system must make a big decision. Tasked with defending us from foreign pathogens, these exquisitely sensitive cells somehow distinguish friend from foe-destroying invaders while tolerating food and helpful bacteria.

28 Jan 2025

Microbial compound offers hope for vitiligo treatment

A natural compound derived from gut-friendly bacteria significantly slows the progression of vitiligo and may restore pigmentation, reports a new Northwestern University pre-clinical study in mice.

28 Jan 2025

T cells grown with new technique offer better cancer defense

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

28 Jan 2025