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High-dose psilocybin shows promise for depression treatment

Researchers compare the effectiveness and acceptability of oral monotherapy with psychedelics for the treatment of depressive symptoms.

27 Aug 2024

NIDDK Catalyst Award funds research on mammary gland's role in metabolic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Catalyst Award program has awarded a $4 million, five-year grant to Prashant Rajbhandari, PhD, Assistant Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at the Mount Sinai Diabetes, Obesity, and Metabolism Institute, to investigate a new frontier in understanding metabolic diseases like obesity and type 2 diabetes.

27 Aug 2024

Urban noise pollution found to have significant negative impact on heart health

Research from two studies in different European cities1,2 highlights that urban noise pollution has a significant negative impact on heart health, according to data presented at ESC Congress 2024.

27 Aug 2024

New insights into γδ T cells could improve treatment for colorectal cancer

The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies.

27 Aug 2024

Menopause transition linked to changes in blood cholesterol and cardiovascular risk

New research presented at the ESC Congress 2024 in London, UK (30 August - 2 September) shows that women in the menopause transition period show changes in their blood cholesterol profiles which could have an adverse impact on their cardiovascular health.

27 Aug 2024

New ESC atlas data highlights disparities in cardiovascular disease mortality

Cardiovascular disease (CVD) remains the most common cause of death across Europe but while CVD mortality rates are generally decreasing, the decline is much less in middle-income than in high-income countries, according to new data from the European Society of Cardiology (ESC) Atlas of Cardiology, published in the European Heart Journal.

27 Aug 2024

Virtual voice technology enhances follow-up care for TAVI patients

Clinical follow-up using virtual voice technology helped identify complications after transcatheter aortic valve implantation (TAVI) with a high degree of patient satisfaction, according to research presented at ESC Congress 2024.

27 Aug 2024

New insights on how melanoma cells resist cancer immunotherapy

Immune checkpoint inhibitors are cancer fighting drugs that help the immune system do its job of detecting and attacking tumor cells.

27 Aug 2024

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

The fight against cancer is an arms race, and one of the most effective weapons in clinicians' arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer.

27 Aug 2024

AI enhances understanding of radiation-induced cardiac arrhythmia risk in lung cancer patients

Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

27 Aug 2024

UQ study unlocks potential for advanced bladder cancer immunotherapy

University of Queensland research could lead to a more effective immunotherapy treatment against bladder cancer.

27 Aug 2024

FDA-approved Alzheimer's drug induces torpor-like state in tadpoles

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer’s.

27 Aug 2024

Dementia Australia welcomes UK approval of lecanemab to tackle Alzheimer’s

Dementia Australia welcomes the decision by the Medicines and Healthcare Products Regulatory Agency to approve Lecanemab for use in the UK.

27 Aug 2024

The role of HPV in male fertility: New data on sperm quality and oxidative stress

Findings indicate HR-HPV infections affect sperm health, increasing oxidative stress and altering cytokine levels, emphasizing HPV's impact on male fertility.

27 Aug 2024

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Semaglutide shows promise in reducing cardiovascular risks in obese patients with heart failure, improving outcomes in a recent large-scale clinical trial.

27 Aug 2024

The significance of CHEK2 variants in cancer risk assessment

A new editorial was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Genotype matters: Personalized screening recommendations for germline CHEK2 variants."

27 Aug 2024

Study identifies Gα13 as a key tumor suppressor in ER+ breast cancer

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive (ER+) breast cancer, this protein acts as a tumor suppressor instead. ER+ breast cancer constitutes about 80 percent of all breast cancer diagnoses, yet nearly 50 percent of women diagnosed with it experience a relapse after initial treatment.

27 Aug 2024

New method uncovers hidden cancer targets

Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding the proteins that the cells rely on to survive.

27 Aug 2024

Study warns of high Medicare costs for semaglutide even with restrictive CVD definition

If Medicare Part D narrowly defines cardiovascular disease, the majority of patients would remain ineligible while new federal spending could still exceed $10 billion

27 Aug 2024

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest.

27 Aug 2024