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Low lipoprotein (a) levels do not cause type 2 diabetes, research shows

New research has shown that, contrary to some previous studies, low levels of lipoprotein (a) – a parcel of fats and protein in the blood – do not cause type 2 diabetes.

29 Aug 2024

Studies uncover mechanisms behind micronuclear instability and cancer progression

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) often observed in aggressive tumor behavior.

29 Aug 2024

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Researchers used real-world clinical data to attempt to emulate a randomized controlled trial testing the effectiveness of two blood thinners, apixaban and warfarin, to prevent stroke in patients with non-valvular atrial fibrillation.

29 Aug 2024

Calorie information on menus: Worsening eating disorders?

Research paper examines the impact of menu calorie labeling on individuals with eating disorders, revealing both potential benefits and significant risks, and calls for further study to better understand these effects.

29 Aug 2024

Acute kidney injury doubles dementia risk, study finds

Study reveals a significant association between acute kidney injury (AKI) and an increased risk of dementia, particularly in cases of severe or recurrent AKI.

29 Aug 2024

Nucleic acids in food show potential to inhibit cancer cell growth

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor Akiko Kojima-Yuasa of the Graduate School of Human Life and Ecology and colleagues.

29 Aug 2024

Exploring the role of suvorexant in reducing delirium among older adults

Delirium is a sudden onset and temporary state of disturbed consciousness or cognition, occurring due to underlying medical issues like fever or alcohol withdrawal.

29 Aug 2024

Multimodal approaches enhance detection of Idiopathic Normal Pressure Hydrocephalus

A recent case report published in Cyborg Bionic Systems details the diagnosis of Idiopathic Normal Pressure Hydrocephalus (iNPH) using multimodality diagnostic approaches, highlighting significant advancements in medical diagnostics and patient care.

29 Aug 2024

Distinct waves of T cells generated by each dose of combination immunotherapy

A new tool for monitoring immune health patterns over time has revealed how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

29 Aug 2024

Study finds diabetes linked to accelerated brain aging, but healthy habits can help

The study links diabetes to accelerated brain aging, highlighting lifestyle factors that could mitigate risks, especially for males with cardiometabolic issues.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Routine lipoprotein(a) testing recommended for all adults

Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.

29 Aug 2024

Smoking cessation reduces major cardiovascular events by almost half, study finds

According to research presented today at ESC Congress 2024, patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a major event by almost 50%.

29 Aug 2024

Weekend sleep could lower heart disease risk by 20%

The demands of the working week, often influenced by school or work schedules, can lead to sleep disruption and deprivation.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Understanding the mechanisms of cardiac fibrosis

The article explores the role of the m6A reader YTHDF1 in cardiac fibrosis, a condition characterized by the excessive accumulation of extracellular matrix proteins, leading to the stiffening of the heart and impaired function. Cardiac fibrosis is a common pathological process in various cardiovascular diseases, including hypertension, myocardial infarction, and heart failure.

29 Aug 2024

New insights into AD pathogenesis and treatment

The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.

29 Aug 2024

Addressing HPV vaccination disparities in girls with mental health conditions

Girls with mental illness or neurodevelopmental conditions are less likely than their peers to be vaccinated with the HPV vaccine that protects against future cervical cancer. This is according to a new registry study from Karolinska Institutet in Sweden published in The Lancet Public Health.

29 Aug 2024

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

A new research paper was published in Oncotarget's Volume 15 on August 26, 2024, entitled, "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties."

29 Aug 2024

AI unveils secrets of protein stability

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein stability-; a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's.

29 Aug 2024