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Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Alcohol use disorders in parents linked to accelerated aging in children

Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have discovered that parents who struggle with alcohol use disorders can pass along symptoms of early aging to their children, affecting them well into adulthood.

8 Aug 2024

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

8 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

A third of NHS shakes and soups diet participants achieve diabetes remission

Researchers assessed insulin-independent diabetes remission by total dietary replacement in England.

8 Aug 2024

Consuming foods with erythritol increases risk of cardiovascular events, study shows

New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke.

8 Aug 2024

Saliva test outperforms blood test in indicating the severity of recurrent respiratory infections in children

A saliva test can more accurately indicate the severity of recurrent respiratory infections in children than the standard blood test.

8 Aug 2024

Short bursts of high-intensity training found effective for stroke survivors

One-minute, short bursts of high-intensity interval training for 19 minutes may be more effective for improving fitness among people six months or more after a stroke than traditional, 20-30 minutes of moderate-intensity exercise sessions, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

8 Aug 2024

New technique reveals abnormalities in motor neurone disease

Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.

8 Aug 2024

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to better understand the underlying mechanisms of cardiovascular disease.

8 Aug 2024

Pro-anorexia content on TikTok may harm women's body image and mental health

Women who spend a lot of time on TikTok -; especially those seeing a lot of pro-anorexia content -; feel worse about their appearance, a new study shows.

8 Aug 2024

Review reveals high rates of opioid dependence among chronic pain patients

A new scientific review of 148 studies enrolling over 4.3 million adult chronic pain patients treated with prescription opioid painkillers has found that nearly one in ten patients experiences opioid dependence or opioid use disorder and nearly one in three shows symptoms of dependence and opioid use disorder.

8 Aug 2024

Coronary atherosclerosis prevalent even in low-risk adults with normal cholesterol levels

Researchers found that coronary atherosclerosis is prevalent in asymptomatic, middle-aged US adults without traditional ASCVD risk factors, and increases with higher levels of LDL-C, non-HDL-C, and apoB.

8 Aug 2024

Breakthrough molecule reverses Alzheimer's symptoms

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer's disease by effectively jumpstarting the brain's memory circuitry.

8 Aug 2024

New evidence challenges hype surrounding cancer blood test

New evidence published by The BMJ today casts doubt on a much-hyped blood test for the NHS that promises to detect more than 50 types of cancer.

8 Aug 2024

Increased skin-to-skin time linked to better neurodevelopment

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found.

8 Aug 2024

High BPA levels linked to increased prostate cancer risk in older men

A study in Nutrients found that higher urinary bisphenol A (BPA) levels are linked to increased prostate-specific antigen (PSA) and higher prostate cancer risk in senior American men. This suggests a need for heightened cancer screening, especially in high-risk groups.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Recombinant shingles vaccine linked to lower dementia risk, especially in women

Study published in Nature Medicine found that the recombinant shingles vaccine is linked to a reduced risk of dementia. This protective effect was particularly notable in females, suggesting a potential advantage of the recombinant vaccine over the live vaccine.

7 Aug 2024