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Higher BPA levels in pregnant mothers linked to autism in sons

Florey researchers have found evidence of higher levels of the plastic chemical bisphenol A (BPA) in pregnant mothers who gave birth to sons with autism.

7 Aug 2024

UK dietitians exhibit significant weight stigma towards themselves and others

In a survey-based study, UK dietitians exhibited significant weight stigma, both towards themselves and towards others.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

Research decodes how cocaine alters dopamine transporter function

You have probably heard of dopamine. The substance also known as the "feel-good hormone".

7 Aug 2024

Sensory nerves drive breast cancer growth and spread, study reveals

Cancer doesn't grow in a vacuum-;each tumor grows in a particular microenvironment within the body and spreads through a tangled web of vasculature and nerves.

7 Aug 2024

Healthy diet and exercise can mitigate genetic risk for type 2 diabetes, study finds

A new study from the University of Eastern Finland is the first in the world to show that a healthy diet and regular exercise reduce the risk of type 2 diabetes even in individuals with a high genetic risk.

7 Aug 2024

Therapeutic targets that impact both cardiac and cerebral functions in CNS neurological disorders

Recent advancements highlight the intricate interplay between the heart and brain, underscoring their profound influence on each other, especially concerning central nervous system (CNS) neurological disorders.

7 Aug 2024

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

A blood test can help predict which preterm babies will go onto develop chronic lung disease, allowing for earlier diagnosis and more targeted treatments, according to a new study.

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

Current challenges in defining, measuring, and treating MS-related fatigue

Kessler Foundation research scientist John DeLuca, PhD, has published a significant clinical article in Journal of Neurology, shedding light on the elusive nature of fatigue in multiple sclerosis (MS) and its implications for treatment.

7 Aug 2024

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

Immunobiologists Robert Schreiber, PhD, (left) and Hussein Sultan, PhD, of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body's healthy cells inadvertently also dampens cancer immunotherapy.

7 Aug 2024

New research uncovers mechanisms behind heart damage from CTLA-4 blockade

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a protein receptor on T immune cells that prevents the cells from killing other cells, such as cancer cells.

7 Aug 2024

NIH study reveals racial and gender disparities in survival rates from bystander CPR

A National Institutes of Health (NIH)-supported study has found race- and sex-based differences in the increased chances of survival from people who received bystander cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest.

7 Aug 2024

NUS study finds 5-HTP enhances sleep quality and gut health in older adults

National University of Singapore (NUS) nutritionists have found that 5-Hydroxytryptophan (5-HTP) supplementation can improve sleep quality in Singaporean older adults, particularly in individuals with poor sleep patterns, and manage their gut microbiome composition.

7 Aug 2024

Hospital discharges linked to higher MRSA risk for family members

Family members of patients recently discharged from the hospital may have a higher risk of getting an antibiotic-resistant infection, often called a superbug, even if the patient was not diagnosed with the same infection, suggesting hospitals play a role in the community spread of resistant bacteria, according to study in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

7 Aug 2024

The evolving nature of infant-caregiver communication

Compared to other mammals, human children are dependent on their caregivers for a remarkably long time. Throughout the ages, they have developed "psychological tactics" to endear themselves to adults and thus enhance their chances of survival. This prolonged dependency is believed to have driven the evolution of complex signaling mechanisms to help infants attract and maintain adult attention.

7 Aug 2024

Understanding the age gap in leukemia survival rates

Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates over 85% compared to 50-75% in adults. Scientists at St. Jude Children's Research Hospital conducted a comprehensive study to understand the biological causes driving this difference. The work, published today in the Journal of Clinical Oncology, provides a blueprint for understanding B-cell acute lymphoblastic leukemia (B-ALL), the most common form of the disease.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Surgery improves long-term outcomes for T-OPLL

Thoracic ossification of the posterior longitudinal ligament (TOPLL) is a rare condition associated with ectopic bone formation in the thoracic spine.

7 Aug 2024