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MESA heart disease risk score performs well even without race modifiers

A version of the MESA heart disease risk score that did not include race predicted heart disease risk just as well as the version that includes race, according to a preliminary study presented today at the American Heart Association's Scientific Sessions 2024.

11 Nov 2024

CKM syndrome leads to elevated cardiovascular disease risk earlier in life

People with chronic kidney disease, Type 2 diabetes or both were predicted to have elevated cardiovascular disease (CVD) risk 8 to 28 years sooner than someone without those conditions, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2024.

11 Nov 2024

Redlining and its lasting impact on heart disease and diabetes

Heart disease, Type 2 diabetes, high blood pressure and obesity were more common and linked to reduced access to healthy foods among people who live in neighborhoods previously subjected to redlining, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2024.

11 Nov 2024

Study reveals liver-brain communication as key to managing circadian eating patterns and obesity

This study uncovers the hepatic vagal nerve's influence on circadian food intake, presenting new avenues for obesity treatment through targeted interventions.

11 Nov 2024

Studies link gut dysbiosis to pancreatic cancer, offering pathways for early detection

The gut microbiome's impact on pancreatic cancer highlights potential for early screening and fecal microbiota transplantation in improving treatment efficacy.

11 Nov 2024

Progress in early detection and screening methods for pancreatic cancer

The evolution of pancreatic cancer screening technologies is pivotal for early detection, addressing key challenges to enhance survival rates and patient care.

11 Nov 2024

Research suggests no need for yellow fever vaccine booster after initial dose

Research shows a single yellow fever vaccine provides lifelong immunity, with breakthrough infections being rare, supporting WHO guidelines on vaccination.

11 Nov 2024

Heat exposure significantly heightens risks for maternal and newborn health

The study reveals that heat exposure increases health risks for pregnant women and their babies, impacting outcomes like preterm birth, low birth weight, and hypertensive disorders.

10 Nov 2024

Genetic links between osteoarthritis and cardiovascular disease reveal hidden common risks

Shared genetic factors may drive both osteoarthritis and cardiovascular disease, suggesting a common genetic basis that influences the development of these diseases.

10 Nov 2024

Does more education reshape your brain?

Researchers found no long-term brain structure changes from an extra year of compulsory education, challenging theories about education's impact on neural development.

10 Nov 2024

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

Breakthrough research reveals how to target malignant DNA in aggressive cancers

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

9 Nov 2024

Pesticide exposure linked to prostate cancer incidence and mortality

Researchers have identified 22 pesticides consistently associated with the incidence of prostate cancer in the United States, with four of the pesticides also linked with prostate cancer mortality. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

9 Nov 2024

Research reveals how children develop understanding of words

A unique study has thrown fascinating new light on how young children begin to understand the meaning of words.

9 Nov 2024

New data map highlights disparities in children’s mental health across the UK

A new data map produced by Centre for Mental Health in collaboration with Kooth has revealed stark disparities in children and young people’s mental health across the four UK nations and between local areas.

9 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

Research shows how public criticism during COVID-19 impacted teacher wellbeing

Intense public pressure on teachers to "get back to school" during the COVID-19 lockdowns deepened an already widespread sense that they were undervalued, and left some actively rethinking their careers, research shows.

8 Nov 2024

New approach reinvigorates exhausted T cells to improve tumor control

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

8 Nov 2024

Uncovering the pathway behind ALS neurodegeneration

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for only two to five years after being diagnosed, according to the Centers for Disease Control and Prevention.

8 Nov 2024

Exploring the protective effects of HSD17B13 in hepatic steatosis

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include metabolic dysfunction-associated steatohepatitis (MASH), alcoholic liver disease (ALD), and hepatitis C virus infection.

8 Nov 2024