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Subjective cognitive decline predicts future dementia risk, study finds

A study in JAMA Psychiatry finds that subjective cognitive decline (SCD) significantly predicts the risk of mild cognitive impairment (MCI), Alzheimer's disease (AD), and all-cause dementia in older adults.

7 Jul 2024

Neuromuscular training reduces chemotherapy-induced neuropathy and improves patient outcomes

Researchers found that neuromuscular training significantly reduces the incidence and severity of chemotherapy-induced peripheral neuropathy, improving patient quality of life and treatment outcomes.

7 Jul 2024

Machine learning identifies cancer-driving mutations at CTCF binding sites

Researchers developed a machine learning tool, CTCF-INSITE, to identify mutational hotspots at persistent CTCF binding sites across various cancers, highlighting their role in genomic structure disruption and cancer progression.

7 Jul 2024

Cutting-edge tools and practices revolutionize gut microbiome research

Research explores cutting-edge tools and best practices for studying gut microbial community metabolism, aiming to enhance our understanding and manipulation of the human gut microbiome for better health outcomes.

7 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Targeted vitamin D supplementation may lower depression risk for deficient individuals, study finds

Targeted vitamin D supplementation for those with low levels can reduce the risk of depression, but shows no significant impact on chronic pain or other conditions.

7 Jul 2024

Study suggests shift work increases risk of premature ejaculation in men

A recent study links shift work and shift work sleep disorder (SWSD) to an increased risk of premature ejaculation (PE) in male workers. The findings highlight how sleep disruptions and prolonged shift work impact reproductive health.

7 Jul 2024

Study suggests cryptocurrency owners share unique psychological and political traits

A recent study links cryptocurrency ownership to various political, psychological, and social traits. Findings show strong correlations with conspiratorial thinking, extremist political views, and 'dark' personality traits like narcissism and psychopathy.

7 Jul 2024

England sees shifting mortality trends with obesity: Cardiovascular deaths decline, neurological and respiratory deaths rise

Obesity-related mortality rates in England show complex trends between 2004 and 2019. While overall mortality rates among obese individuals declined, the study highlights shifting causes of death, including an increase in neurological and respiratory deaths.

7 Jul 2024

Breakthrough humanized mouse model offers new insights for immunotherapy development

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.

5 Jul 2024

Smoking identified as key factor in accelerated cognitive decline

Smoking may be among the most important lifestyle factors affecting how quickly our cognitive skills decline as we age, suggests a new study led by UCL researchers.

5 Jul 2024

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

An international panel of experts led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, under the umbrella of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, has produced a consensus statement on sex and gender disparities in resilience to Alzheimer's disease and call for incorporating these differences in future research.

5 Jul 2024

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

5 Jul 2024

Why do aortic aneurysms form in specific locations?

The sites where vascular aneurysms typically form have a predilection from the outset, even in healthy people. This is shown by a study conducted by medical researchers from Bochum and Bonn.

5 Jul 2024

DNA repair mutations act as a switch for bowel cancer

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical Center Utrecht.

5 Jul 2024

Baby boys more likely to achieve HIV cure or remission after in-utero infection

Baby girls are more likely to acquire HIV from their mothers during pregnancy or childbirth than infant boys, who are conversely more likely to achieve cure or remission, researchers say in a new study that sheds light on the gender differences in immune systems.

5 Jul 2024