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Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Experiencing gratitude may increase longevity among older adults

Experiencing gratitude may help older adults live longer, according to a new study from Harvard T.H. Chan School of Public Health.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

Exercise boosts tumor-killing white blood cells in breast cancer patients

A new Finnish study from University of Turku shows that already a 30-minute exercise can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer patients.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Research reveals link between rooms with high ceilings and poorer examination results

Ever wondered why you performed worse than expected in that final university exam that you sat in a cavernous gymnasium or massive hall, despite countless hours, days and weeks of study? Now you have a genuine reason – high ceilings.

3 Jul 2024

Does long-term air pollution exposure lead to loss of independence in later life?

The association between exposure to air pollutants over extended periods and the loss of independence among older adults.

3 Jul 2024

Digital screening for depression: Does automated feedback help?

The efficacy of two versions of automated feedback following internet-based depression screening on the severity of depression.

3 Jul 2024

New study supports expanded access to HPV testing via self-collection

In 2019, more than 12,000 new cases of cervical cancer were diagnosed and upwards of 4,000 patients died in the U.S. The causal link between human papillomavirus (HPV) infection and the development of cervical cancer is well documented. Cervical cancer screening guidelines are currently in the review process for updates. On May 15, 2024, the U.S. Food and Drug Administration (FDA) approved patient-collected testing (vaginal self-collection) for HPV. Several countries, including the Netherlands and Australia, have introduced HPV self-collection as a part of their national screening programs.

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

Gene mutation explains heart defects in children

A new groundbreaking study sheds light on a medical question scientists have long wondered: why do 40 per cent of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain.

3 Jul 2024

Gene discovery points to oxytocin for depression

While investigating two boys from different families with severe obesity, anxiety, autism, and behavioural problems triggered by sounds or smells, a team led by scientists at the University of Cambridge, UK, and Baylor College of Medicine, Houston, USA, discovered that the boys were missing a single gene, known as TRPC5, which sits on the X chromosome.

3 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa-;a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024