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New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Cancer immunotherapies--drugs that work by making a patient's immune system better at spotting and destroying tumor cells--are increasingly generating headlines. A number of these drugs are now being used for the treatment of melanoma, lung, and kidney cancers, and are showing promise in clinical trials with other diseases as well.

3 Jun 2016

Fluctuations in tRNA may play vital role in cancer metastasis

At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA.

3 Jun 2016

New research explores women’s perspective about medication use during pregnancy

Pregnant women overestimate the risks of taking over the counter and prescribed medication - according to new research from the University of East Anglia.

3 Jun 2016

Maternal vaccination against influenza can reduce flu risk in newborns

Each year, influenza causes between 250,000 and half a million deaths around the world. Pregnant women and young infants have a higher risk of complications related to influenza; these complications can easily lead to death.

3 Jun 2016

Scientists identify cellular mechanisms of altered skin wound repair in elderly patients

Each injury means a little more as individuals age -- more impact and more healing time.

3 Jun 2016

Study reinforces significance of raising young children in stimulating environments

A recent study shows that infants and toddlers take longer to notice new visual stimuli and are less accurate in their gaze than adults, but slowly improve as they age. The findings reinforce the importance of raising young children in stimulating environments, and set an important baseline as detection of developmental disorders increasingly rely on tracking eye movements.

3 Jun 2016

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Testing for a common genetic variant may help reveal which patients face an increased risk of developing kidney damage following heart surgery. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, may help investigators develop therapeutic strategies to mitigate this damage.

3 Jun 2016

Lund researchers identify four genetic keys that can unlock code, reprogram skin cells

Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead.

3 Jun 2016

Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Intestinal stem cells are among the most rapidly dividing cells in the body, busily creating new cells to replace the ones that are constantly being sloughed off. But unlike stem cells elsewhere in the body, those in the intestine are hidden away, and for good reason, it turns out.

3 Jun 2016

Forgetting is key to good memory

Scientists in Florida have discovered a new protein that is needed for normal forgetting by the human brain. It appears that forgetting is a critical part of the normal management of memories. Identifying the protein essential to this normal forgetting may help researchers to gain further insight into how the human memory works.

3 Jun 2016

Eating walnuts may offer protection against colon tumors

Eating walnuts may change gut bacteria in a way that suppresses colon cancer, researchers led by UConn Health report in the journal Cancer Prevention Research.

3 Jun 2016

CNIO researchers avoid genetic manipulation to create lab mice with extra-long telomeres

The Telomeres and Telomerase Group at the Spanish National Cancer Research Centre, in collaboration with the Centre's Transgenic Mice Core Unit, has succeeded in creating mice in the laboratory with hyper-long telomeres and with reduced molecular ageing, avoiding the use of what to date has been the standard method: genetic manipulation.

3 Jun 2016

New dietary supplement can prevent, reverse massive brain cell loss

A dietary supplement containing a blend of thirty vitamins and minerals--all natural ingredients widely available in health food stores--has shown remarkable anti-aging properties that can prevent and even reverse massive brain cell loss, according to new research from McMaster University.

3 Jun 2016

New method helps quantify HSATII RNA in blood serum of pancreatic cancer patients

Pancreatic ductal adenocarcinoma is one of the most aggressive and deadliest forms of cancer. Treatment options are limited because symptoms typically do not appear until the disease is advanced and complete surgical resection of tumors is not possible.

3 Jun 2016

Few commercial weight loss programs show promise of benefit for diabetic patients

Johns Hopkins scientists who indirectly investigated the blood sugar effects of 10 (out of 32 selected) commercial weight loss programs say a few show promise of benefit for diabetic patients, but far more rigorous research is needed before doctors can wholeheartedly recommend them.

3 Jun 2016

Researchers developing more accessible way to monitor brain health

Simon Fraser University researchers hope that a brain vital-sign test becomes as routine during a doctor's check-up as taking a blood pressure or heart rate measurement.

3 Jun 2016

New research highlights value of exercise for humans looking to keep their brains fit

The relentless desire by mice to run on cage "exercise" wheels has helped explain at a molecular level how exercise benefits a mammal's brain.

2 Jun 2016

New FDA draft guidelines place tighter restrictions on surgical practices using tissue-based regenerative therapies

The therapeutic use of human cell and tissue products is highly regulated by the U.S. government, but a specific exception allows surgeons to harvest, manipulate, and implant tissues in many commonly performed procedures.

2 Jun 2016

Understanding mechanisms of aortic pathology to improve care

Aortic disease, including aortic aneurysm and aortic dissection, is an important cause of cardiovascular morbidity and death. There have been exciting developments in caring for patients with aortic aneurysm and dissection, including great advances in diagnosis and endovascular therapies.

2 Jun 2016

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

Medical Research News

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Fluctuations in tRNA may play vital role in cancer metastasis

New research explores women’s perspective about medication use during pregnancy

Maternal vaccination against influenza can reduce flu risk in newborns

Scientists identify cellular mechanisms of altered skin wound repair in elderly patients

Study reinforces significance of raising young children in stimulating environments

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Lund researchers identify four genetic keys that can unlock code, reprogram skin cells

Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Forgetting is key to good memory

Eating walnuts may offer protection against colon tumors

CNIO researchers avoid genetic manipulation to create lab mice with extra-long telomeres

New dietary supplement can prevent, reverse massive brain cell loss

New method helps quantify HSATII RNA in blood serum of pancreatic cancer patients

Few commercial weight loss programs show promise of benefit for diabetic patients

Researchers developing more accessible way to monitor brain health

New research highlights value of exercise for humans looking to keep their brains fit

New FDA draft guidelines place tighter restrictions on surgical practices using tissue-based regenerative therapies

Understanding mechanisms of aortic pathology to improve care

Retroviral replicating vector can extend lives of brain cancer patients

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