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New mouse model offers more insight into development of ASD in humans

A new mouse model, developed by researchers at the University of Wisconsin-Madison, is the first to show that when more of a specific biological molecule moves between different parts of nerve cells in the mouse brain, it can lead to behaviors that resembles some aspects of autism spectrum disorder (ASD) in humans.

2 Jun 2016

Study finds beer consumption may protect against Aβ aggregation in the brain

While most people will agree that excessive consumption of alcohol can have a detrimental effect on the brain, there is less agreement regarding the effects of light or moderate drinking.

2 Jun 2016

Scientists use optogenetics technique to increase memory in mice brain

Raül Andero Galí, one of the heads of the "Neurobiology of Stress and Addiction" research group at the Institut de Neurociències of the Universitat Autònoma de Barcelona and researcher at Harvard University, published an article in which, for the first time in Spain, optogenetics was used to increase memory.

2 Jun 2016

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure.

2 Jun 2016

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease.

2 Jun 2016

New HET wearable system may help track user’s wellness to predict asthma attacks

Researchers have developed an integrated, wearable system that monitors a user's environment, heart rate and other physical attributes with the goal of predicting and preventing asthma attacks.

2 Jun 2016

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Physicians have long used magnetic resonance imaging (MRI) to detect cancer but results of a University of California San Diego School of Medicine study describe the potential use of restriction spectrum imaging (RSI) as an imaging biomarker that enhances the ability of MRI to differentiate aggressive prostate cancer from low-grade or benign tumors and guide treatment and biopsy.

2 Jun 2016

Prenatal mild viral assault may cause central nervous system malfunctions in children

Babies born to mothers whose immune systems had to grapple with a viral assault -- even a mild one -- have increased risk of brain and central nervous system abnormalities, according to a new study.

2 Jun 2016

Infection may trigger development of Alzheimer's disease

A growing body of research on Alzheimer's disease suggests an infectious trigger for the development of the disease. According to Brian Balin, PhD, professor of pathology and chair of bio-medical sciences at Philadelphia College of Osteopathic Medicine, this could be the key to stopping the destructive process of Alzheimer's before it even starts.

2 Jun 2016

Excess phosphates in foods may lead to abnormally high blood pressure

Excess consumption of phosphate over-activates nerves that raise blood pressure, leading to abnormally high blood pressure, a new study in the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology reports.

2 Jun 2016

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Researchers have discovered three new inhibitors of insulin-regulated aminopeptidase (IRAP), compounds shown to improve cognitive functions in animal models of human disorders.

2 Jun 2016

Right carbohydrate intake linked to healthy aging

Most people know that a diet high in fiber helps to keep us "regular." Now Australian researchers have uncovered a surprising benefit of this often-undervalued dietary component.

2 Jun 2016

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

Since September 11, 2001, an estimated 60,000 U.S. military service members have been injured in combat during the Afghanistan and Iraq wars. Nearly 45,000 of all combat injuries are caused by improvised explosive devices, also known as IEDs.

2 Jun 2016

Correcting defective p73 gene function may be promising therapeutic strategy for chronic lung diseases

Rising global air pollution and increasing smoking prevalence in many developing nations will likely lead to a growing incidence of lung diseases such as chronic obstructive pulmonary disease (COPD), which currently affects more than 330 million people worldwide, is the third-leading cause of death and carries an estimated healthcare cost of $2.1 trillion.

2 Jun 2016

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Researchers at the University of Utah compared the therapeutic potential of umbilical cord-derived sub-epithelial cells (UC-SECs), bone marrow-derived mesenchymal stem cells (BM-MSCs) and induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) -- all derived from human tissue -- along with genes (S100a1 and SDF-1a) and growth factor (VEGF165) to evaluate how injected biologics might enhance cardiac function in mice modeled with myocardial infarction (MI; commonly referred to as heart attack).

2 Jun 2016

Clinical trial to evaluate ability of MRI to improve prostate cancer diagnosis

The Movember Foundation, the Ontario Institute for Cancer Research and Prostate Cancer Canada today announced $3 million in funding for a new Phase III clinical trial to evaluate if magnetic resonance imaging (MRI) can replace the current standard of care to diagnose prostate cancer.

2 Jun 2016

Alcoholic individuals may form stronger memory associations with alcohol-related environmental stimuli

Drug-cue associations can have a powerful influence over individuals with drug and alcohol use disorders, often leading to relapse in those attempting to stay abstinent. Few studies have investigated how drugs affect learning or memory for drug-associated stimuli in humans.

2 Jun 2016

$CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory$

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

A two-year, multi-center clinical study with 167 patients with class III-IV refractory angina randomized to low and high dose CD34+ cells or placebo has revealed that patients who received either a high or low dose of CD34 -- a member of a family of proteins that have an impact on vascular-associated tissue -- cells had a significant reduction in angina frequency over patients who received placebo.

2 Jun 2016

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

Researchers should include laboratory mice that are old and obese in their studies of immunotherapy treatments for cancer, according to a review article by Saint Louis University scientists.

2 Jun 2016

Testing for maternal alcohol biomarkers in blood may help identify pregnancies at high FAS risk

It is well known that drinking during pregnancy can lead to fetal alcohol syndrome (FAS) in the offspring. Unfortunately, not all pregnant women are truthful about their levels of drinking.

2 Jun 2016

Medical Research News

New mouse model offers more insight into development of ASD in humans

Study finds beer consumption may protect against Aβ aggregation in the brain

Scientists use optogenetics technique to increase memory in mice brain

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

New HET wearable system may help track user’s wellness to predict asthma attacks

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Prenatal mild viral assault may cause central nervous system malfunctions in children

Infection may trigger development of Alzheimer's disease

Excess phosphates in foods may lead to abnormally high blood pressure

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Right carbohydrate intake linked to healthy aging

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

Correcting defective p73 gene function may be promising therapeutic strategy for chronic lung diseases

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Clinical trial to evaluate ability of MRI to improve prostate cancer diagnosis

Alcoholic individuals may form stronger memory associations with alcohol-related environmental stimuli

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

Testing for maternal alcohol biomarkers in blood may help identify pregnancies at high FAS risk

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