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Women taking birth control pill less likely to suffer serious knee injuries

Researchers from The University of Texas Medical Branch at Galveston have found that women who take the birth control pill, which lessen and stabilize estrogen levels, were less likely to suffer serious knee injuries. The findings are currently available in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine.

21 Mar 2016

Study assesses acceptability of alternative drug to prevent malaria among pregnant women in Kenya

Researchers at LSTM, working with colleagues at the Centres for Disease Control and Prevention USA, the Kenya Medical Research Institute, and from the London School of Hygiene and Tropical Medicine, have completed a study to assess the acceptability among pregnant women and health providers in Kenya of a new drug as an alternative to the standard drug used to prevent malaria in pregnancy.

21 Mar 2016

New molecular probe can detect different amyloid deposits in human tissues

A team of scientists at Sweden's Linköping University have developed a molecular probe that can detect an array of different amyloid deposits in several human tissues. This new probe is extremely sensitive and was used at very low concentrations to correctly identify every positive amyloidosis sample when compared to the traditional clinical tests.

21 Mar 2016

Sitting for all or much of the day could affect a person’s overall health

Despite their popularity, the effectiveness of stand-up desks and other strategies aimed at getting people to sit less at work is largely uncertain, according to a systematic review of published research conducted by Cochrane Collaboration authors

21 Mar 2016

IUPUI investigators use stem cells to identify potential therapies to prevent glaucoma

Using stem cells derived from human skin cells, researchers led by Jason Meyer, assistant professor of biology, along with graduate student Sarah Ohlemacher of the School of Science at Indiana University-Purdue University Indianapolis, have successfully demonstrated the ability to turn stem cells into retinal ganglion cells (RGCs), the neurons that conduct visual information from the eye to the brain.

21 Mar 2016

Researchers describe generation of plasma cell-specific antibody from immunized lampreys

Antibody-secreting plasma cells arise from B cell precursors and are essential for adaptive immune responses against invading pathogens. Plasma cell dysfunction is associated with autoimmune and neoplastic disorders, including multiple myeloma.

21 Mar 2016

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

21 Mar 2016

Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Preeclampsia is characterized by elevated blood pressure in the second half of pregnancy and impaired blood flow to the placenta, which increases the risk of premature birth and pregnancy complications.

21 Mar 2016

Educating citizen scientists can boost integrity of scientific research

Maria Barraza has been a Community Health Worker for 25 years, providing health services and facilitating research studies in underserved areas where disparities are most prevalent. In her role, Barraza contributes to the development and implementation of community and clinic-based research studies

21 Mar 2016

Research shows how recreational ketamine abuse harms the bladder

Research conducted by scientists at the University of York has revealed how recreational ketamine abuse damages the bladder

21 Mar 2016

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report.

21 Mar 2016

Ovarian serous cancer patients with overexpression of HER4 protein less likely respond to chemotherapy

Moffitt Cancer Center researchers discovered that patients with ovarian serous cancer and an overexpression of the HER4 protein are less likely to respond to chemotherapy and have a lower rate of survival.

21 Mar 2016

Novel compound shows promise as potential treatment for acute myeloid leukemia

A novel compound has shown promise in preclinical studies as a treatment for acute myeloid leukemia, more than doubling median days of survival even in a drug-resistant form of the disease.

21 Mar 2016

Scientists discover neural pathway that induces forgetting by actively erasing memories

They say that once you've learned to ride a bicycle, you never forget how to do it. But new research suggests that while learning, the brain is actively trying to forget. The study, by scientists at EMBL and University Pablo Olavide in Sevilla, Spain, is published today in Nature Communications

21 Mar 2016

MRX-2843 treatment improves survival of acute myeloid leukemia patients

Acute myeloid leukemia (AML) is a cancer of myeloid stem cells that develops in both adult and pediatric populations. Mutations that cause hyperactivation of the FMS-like tyrosine kinase 3 (FLT3) are commonly found in AML, and several clinical trials are testing FLT3 inhibitors.

21 Mar 2016

Study suggests need for better strategy to reduce fatalities after non-surgical treatment for blocked arteries

Despite the successful adoption of modern techniques, new research from the Universities of Keele and Manchester suggests more can be done to reduce fatalities following a non-surgical treatment for blocked arteries.

21 Mar 2016

Trimeprazine improves β cell function, slows progression of diabetes

β cells in pancreatic islets are responsible for producing insulin, which is essential to regulate blood glucose homeostasis. In type 1 diabetes, pancreatic β cells are destroyed due to an autoimmune attack, whereas in type 2 diabetes, pancreatic β cells may have deficiencies in secreting insulin or insulin-responding tissues can become insulin resistant.

21 Mar 2016

Public health benefits of using more recycled water

Expanding the use of recycled water would reduce water and energy use, cut greenhouse gas emissions and benefit public health in California -- which is in the midst of a severe drought -- and around the world.

21 Mar 2016

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Cobimetinib (trade name: Cotellic) has been approved since November 2015 in combination with vemurafenib for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation.

21 Mar 2016

Dental study to elicit perceptions of oral health among youth

Today at the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Carl Maida, University of California, Los Angeles, USA, will present a study titled "Child and Adolescent Perceptions of Oral Health: Life Course Perspectives." The AADR Annual Meeting is being held in conjunction with the 40th Annual Meeting of the Canadian Association for Dental Research.

21 Mar 2016

Medical Research News

Women taking birth control pill less likely to suffer serious knee injuries

Study assesses acceptability of alternative drug to prevent malaria among pregnant women in Kenya

New molecular probe can detect different amyloid deposits in human tissues

Sitting for all or much of the day could affect a person’s overall health

IUPUI investigators use stem cells to identify potential therapies to prevent glaucoma

Researchers describe generation of plasma cell-specific antibody from immunized lampreys

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Educating citizen scientists can boost integrity of scientific research

Research shows how recreational ketamine abuse harms the bladder

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

Ovarian serous cancer patients with overexpression of HER4 protein less likely respond to chemotherapy

Novel compound shows promise as potential treatment for acute myeloid leukemia

Scientists discover neural pathway that induces forgetting by actively erasing memories

MRX-2843 treatment improves survival of acute myeloid leukemia patients

Study suggests need for better strategy to reduce fatalities after non-surgical treatment for blocked arteries

Trimeprazine improves β cell function, slows progression of diabetes

Public health benefits of using more recycled water

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Dental study to elicit perceptions of oral health among youth

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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