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Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Patients with a rare, genetic form of diabetes often are misdiagnosed as having type 2 diabetes because the two share symptoms.

18 Mar 2016

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

A new breast cancer staging system developed by researchers at The University of Texas MD Anderson Cancer Center finds that incorporating tumor biology is a critical prognostic indicator for women who undergo neoadjuvant, or pre-surgical, therapy for breast cancer.

18 Mar 2016

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine approved yesterday a $6.3 million grant to a research team from the University of California, San Diego School of Medicine and University of California, Davis to pursue a novel human embryonic stem cell-based therapy to rescue and restore neurons devastated by amyotrophic lateral sclerosis or ALS.

18 Mar 2016

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers.

18 Mar 2016

UNIGE researchers identify new recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases known as "recessive" occur only when both the father and the mother are healthy carriers of the same defective gene which can be passed down to their children.

18 Mar 2016

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

National Institutes of Health-funded scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals.

18 Mar 2016

Secondary non-Hodgkin's lymphoma a concern for CML patients using TKIs

Patients with chronic myeloid leukaemia who use the tyrosine kinase inhibitor imatinib may be three to four times more likely to develop non-Hodgkin's lymphoma than the general population, study findings indicate.

17 Mar 2016

Vascular events in CML may not be linked to TKI therapy

The increased risk of vascular events observed among elderly patients with chronic myeloid leukaemia, compared with patients without cancer, may not be driven by tyrosine kinase inhibitor therapy, US researchers suggest.

17 Mar 2016

Older types of arthritis medicine appear to be dangerous for the heart

Many Danes are prescribed NSAIDs for the treatment of painful conditions, fever and inflammation. But the treatment also comes with side effects, including the risk of ulcers and increased blood pressure.

17 Mar 2016

USF receives $9 million NIH grant to study unique treatment for age-related hearing loss

Researchers in the University of South Florida's Global Center for Hearing and Speech Research, recognized as the world's top research center for age-related hearing loss, have received a five-year, $9 million grant from the National Institutes of Health to study two unique ways to treat age-related hearing loss (ARHL).

17 Mar 2016

New subtype of bladder cancer shares molecular signatures with breast cancer

Bladder cancer is the fourth most common cancer among men in the United States. While low-grade tumors have a very favorable prognosis, muscle-invasive and metastatic tumors have poorer survival rates.

17 Mar 2016

Students who eat breakfast at school less likely to be obese than students who skip breakfast

Middle school students who eat breakfast at school -- even if they have already had breakfast at home -- are less likely to be overweight or obese than students who skip breakfast, says a new study by the Community Alliance for Research and Engagement at the Yale School of Public Health and the Rudd Center for Food Policy & Obesity at the University of Connecticut.

17 Mar 2016

Study: Prenatal exposure to PAH leads to mental health problems in children

Exposure to common air pollutants during pregnancy may predispose children to problems regulating their thoughts, emotions, and behaviors later on, according to a new study led by researchers at the Columbia Center for Children's Environmental Health within Columbia University's Mailman School of Public Health and New York State Psychiatric Institute.

17 Mar 2016

Tests for Alzheimer’s detection in women may need improving

A new study has shown that women may have a better memory for words than men in the early stages of Alzheimer’s disease, despite evidence of similar levels of shrinkage in the brain area responsible for verbal memory.

17 Mar 2016

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year.

From Beckman Coulter Life Sciences - Centrifugation 17 Mar 2016

Real-life data show feasibility of imatinib discontinuation in CML

Italian research shows that long-term imatinib discontinuation is feasible outside of a clinical trial setting for patients with chronic myeloid leukaemia who achieve stable undetectable molecular disease with front-line treatment.

17 Mar 2016

Women's verbal memory advantage may mask cognitive decline

Women with amnestic mild cognitive impairment have better verbal memory skills than their male counterparts during the early stages of hippocampal decline.

17 Mar 2016

Researchers find major gap in treatment for AF patients at higher risk for stroke

Nearly half of all atrial fibrillation (AF) patients at the highest risk for stroke are not being prescribed blood thinners by their cardiologists, according to a new study by researchers at University of California, San Diego School of Medicine and University of California, San Francisco.

17 Mar 2016

Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

Could an unhealthy diet and lack of exercise be making you age faster? Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice.

17 Mar 2016

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Repairing the brain's "house-cleaning function," which could help people with Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and 100 other diseases, is the focus of recently funded research at Washington State University.

17 Mar 2016

Medical Research News

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

UNIGE researchers identify new recessive disease

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

Secondary non-Hodgkin's lymphoma a concern for CML patients using TKIs

Vascular events in CML may not be linked to TKI therapy

Older types of arthritis medicine appear to be dangerous for the heart

USF receives $9 million NIH grant to study unique treatment for age-related hearing loss

New subtype of bladder cancer shares molecular signatures with breast cancer

Students who eat breakfast at school less likely to be obese than students who skip breakfast

Study: Prenatal exposure to PAH leads to mental health problems in children

Tests for Alzheimer’s detection in women may need improving

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Real-life data show feasibility of imatinib discontinuation in CML

Women's verbal memory advantage may mask cognitive decline

Researchers find major gap in treatment for AF patients at higher risk for stroke

Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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