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Researchers identify genetic mutations that lower complications associated with diabetes

The most significant complications of diabetes include diabetic retinal disease, or retinopathy, and diabetic kidney disease, or nephropathy. Both involve damaged capillaries.

11 Feb 2016

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

Unlike normal cells, stem cells are pluripotent -- they can become any cell type, which makes them powerful potential treatments for diseases such as diabetes, leukemia and age-related blindness. However, maintaining this versatility until the time is right is a major challenge.

11 Feb 2016

Pregnancy may reduce PTSD symptoms in at-risk women

For most women, expecting a baby brings intense joy --and a fair amount of worry. But what about women who have lived through something awful enough to cause post-traumatic stress disorder? Contrary to what researchers expected, a new study shows that pregnancy may actually reduce their PTSD symptoms. Or at the least, it won't cause a flare-up.

11 Feb 2016

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle.

11 Feb 2016

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Researchers from Kumamoto University, Japan have identified a protein that limits the severity of Alport syndrome, a type of genetic kidney disease. The finding can provide clues that point toward new therapeutic approaches for Alport syndrome.

11 Feb 2016

New technique could help detect harmful PAMP molecules in certain processed foods

Our favourite foods could be made healthier thanks to a new technique developed by the University of Leicester which has identified harmful bacterial molecules in certain processed foods such as burgers and ready meals.

11 Feb 2016

TSRI scientists develop new screening device for drug discovery

Screening large "libraries" of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.

11 Feb 2016

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

New research uncovers a cascade of reactions within nerve cells that relay sensations of pain associated with inflammation. The findings, which are published in the British Journal of Pharmacology, indicate that drugs designed to curb this pathway may help relieve inflammatory pain in sufferers.

11 Feb 2016

Neutrophils promote cardiac repair

Following an acute heart attack, immune cells called neutrophils coordinate an inflammatory response which can exacerbate the damage to the organ. Now researchers from Ludwig-Maximilians-Universitaet in Munich have shown that neutrophils also promote cardiac repair.

11 Feb 2016

Dementia incidence highest in African Americans, lowest in Asian Americans

The first study to look at dementia risk in a population representing the diversity of the United States finds dementia incidence to be highest in African Americans and lowest in Asian Americans. The rate of occurrence of dementia in African Americans was found to be 65 percent higher than Asian Americans.

10 Feb 2016

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits.

10 Feb 2016

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Could a kinase inhibitor some doctors prescribe to keep blood flowing after brain surgery be used to treat neurodegeneration? New research suggests it might be worth exploring the question.

10 Feb 2016

Cranberry capsules more effective in lowering UTI risk than juice

A UTI is an infection in any part of the urinary system, kidneys, bladder or urethra. They are more common in women and affect more than 3 million Americans per year. Many in the population will turn to sipping on a cranberry juice cocktail to alleviate their symptoms, but, according to a Texas A&M Health Science Center urologist, drinking cranberry juice to treat a UTI is little more than an old wives' tale.

10 Feb 2016

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Pediatric acute lymphoblastic leukemia (ALL) patients treated with chemotherapy alone remain at risk for attention and learning problems that persist after treatment ends, according to St. Jude Children's Research Hospital investigators.

10 Feb 2016

Study sheds light on role of red raspberries in metabolically-based chronic diseases

Components in red raspberries may have anti-inflammatory, anti-oxidative and metabolic stabilizing activity, according to a comprehensive review of the available scientific literature published in the January issue of Advances in Nutrition.

10 Feb 2016

BMJ, UCSF team up to provide self-study online modules for healthcare researchers

BMJ, a global healthcare knowledge provider, has joined forces with the University of California, San Francisco, a world leader in biomedical research, to provide self-study online modules for doctors and healthcare researchers to develop their research skills and become published authors.

10 Feb 2016

LMU researchers identify new drug target for atherosclerosis

The enzyme Dicer processes RNA transcripts, cutting them into short segments that regulate the synthesis of specific proteins. An Ludwig-Maximilians-Universitaet in Munich team has shown that Dicer promotes the development of atherosclerosis, thus identifying a new drug target.

10 Feb 2016

Minimum legal drinking age legislation can have major impact on young drivers in Canada

A new study led by a Northern Medical Program (NMP) researcher shows that alcohol-impaired driving crimes spike immediately after the minimum legal drinking age (MLDA) is reached, indicating that minimum legal drinking age legislation in Canada can have a major impact on young drivers.

10 Feb 2016

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

Washington State University researchers have determined how a protein that helps cells fight viruses can also cause genetic mutations that lead to cancer.

10 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Medical Research News

Researchers identify genetic mutations that lower complications associated with diabetes

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

Pregnancy may reduce PTSD symptoms in at-risk women

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Kumamoto University researchers identify protein that limits severity of Alport syndrome

New technique could help detect harmful PAMP molecules in certain processed foods

TSRI scientists develop new screening device for drug discovery

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

Neutrophils promote cardiac repair

Dementia incidence highest in African Americans, lowest in Asian Americans

Five researchers named winners of 2016 Elsevier Foundation Awards

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Cranberry capsules more effective in lowering UTI risk than juice

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Study sheds light on role of red raspberries in metabolically-based chronic diseases

BMJ, UCSF team up to provide self-study online modules for healthcare researchers

LMU researchers identify new drug target for atherosclerosis

Minimum legal drinking age legislation can have major impact on young drivers in Canada

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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