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UM SOM researchers reveal genetic makeup of various strains of E. coli

A multi-disciplinary group of researchers at the University of Maryland School of Medicine have for the first time determined the genetic makeup of various strains of E. coli, which every year kills hundreds of thousands of people around the world.

9 Feb 2016

Study: Only one-third of patients receive living donor kidney transplant pre-emptively

A kidney transplant is a life-changing and life-saving procedure. Yet, a new study conducted by Mayo Clinic and the University of Michigan shows that only one-third of patients who ultimately receive a living donor kidney transplant receive it pre-emptively (i.e., before starting dialysis). Less than two-thirds receive a transplant either pre-emptively or within a year of starting dialysis.

9 Feb 2016

New evidence highlights benefits and harms of using artificial mesh for surgical repair of vaginal prolapse

New evidence published today highlights benefits and harms of using artificial mesh when compared with tissue repair in the surgical treatment of vaginal prolapse. Slightly better repair with mesh needs to be weighed carefully against increased risk of harms.

9 Feb 2016

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

9 Feb 2016

New pain management strategies key to maximizing patient outcomes after TKR procedures

According to a new literature review in the February issue of the Journal of the American Academy of Orthopaedic Surgeons, a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) procedures, in conjunction with newer pain management strategies, is key to maximizing patient outcomes.

9 Feb 2016

TBX5 gene expression could play key role in congenital heart disease

Congenital heart disease is the most common birth defect and the leading cause of all infant deaths in the United States. Mutations in the gene TBX5 have been shown to cause both rare and more prevalent forms of congenital heart disease, yet the underlying mechanisms have remained unclear.

9 Feb 2016

Gut microbes influence severity of malaria

Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study co-authored by researchers at the University of Tennessee, Knoxville, and the University of Louisville.

9 Feb 2016

Benzodiazepine dementia risk refuted

Benzodiazepines, commonly used by older adults to manage sleep, anxiety and depressive disorders, do not increase the risk of dementia or hasten cognitive decline, study findings show.

8 Feb 2016

Favourable safety, disease control for proton radiotherapy in paediatric medulloblastoma

Proton radiotherapy has an acceptable safety and disease control profile in paediatric medulloblastoma patients, according to research published in The Lancet Oncology.

8 Feb 2016

Past experience alters the brain circuitry responsible for object recognition

New research from the University of Guelph on the brain and memory could help in developing therapies for people with schizophrenia and Alzheimer's disease.

8 Feb 2016

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Renal cell carcinoma can sometimes spread to the inferior vena cava (IVC), the body's largest vein, posing a threat to the heart and brain. Robotic nephrectomy for inferior vena cava tumor thrombus has favorable outcomes in selected patients compared with open surgery, which can have a high rate of complications, report surgeons in The Journal of Urology.

8 Feb 2016

Findings may help states optimize tobacco cessation, cancer control programs

A new analysis indicates that states' Web-based and phone-based tobacco cessation programs can help people quit smoking, but certain personal characteristics may lead individuals to prefer one type of program over the other.

8 Feb 2016

New study links sleep problems to poor academic performances among teens

High school students going to bed between 10 and 11 p.m. on weekdays get better grades. There is a strong relationship between sleep problems and poor academic performances among adolescents, a new study demonstrates.

8 Feb 2016

Study shows association between traffic-related air pollution and dark spots on the skin

A largescale study that included women from Germany and China has demonstrated a link between levels of traffic-related air pollution and air pollution-associated gases with the formation of dark spots on the skin, known as lentigenes. The most pronounced changes were observed on the cheeks of Asian women over the age of 50.

8 Feb 2016

Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Researchers at King's College London and the Wellcome Trust Sanger Institute in the United Kingdom have for the first time demonstrated a direct link between the Wbp2 gene and progressive hearing loss. The scientists report that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse as well as in two clinical cases of children with deafness with no other obvious features.

8 Feb 2016

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels.

8 Feb 2016

Study reveals association between DNA methylation and type 2 diabetes

Researchers from the Hospital del Mar Medical Research Institute have found an epigenetic mechanism implicated in the regulation of blood sugar. The study, published in the journal Molecular Human Genetics, reveals that the methylation of the TXNIP gene is associated with diabetes mellitus type 2 and, in particular, average blood glucose levels.

8 Feb 2016

University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

The University of Oxford and SomaLogic announced today that they have agreed to undertake a number of collaborative projects that will employ SomaLogic's proprietary SOMAmer reagents and SOMAscan assay technologies to discover and characterize protein biomarkers for a range of clinical diseases and conditions.

8 Feb 2016

Effective treatments for knee instability may help reduce falls in older adults

Symptoms of knee instability in older adults may indicate an increased risk of falling and of experiencing the various physical and psychological effects that can result from falling, according to a study published in Arthritis Care & Research, a journal of the American College of Rheumatology.

8 Feb 2016

Hallucinogens may have therapeutic potential against intimate partner violence

Evidence in a study led by researchers at the University of British Columbia along with University of Alabama at Birmingham School of Public Health Associate Professor Peter S. Hendricks, Ph.D., suggests hallucinogens such as psilocybin or LSD may have therapeutic potential for reducing intimate partner violence, or IPV.

8 Feb 2016

Medical Research News

UM SOM researchers reveal genetic makeup of various strains of E. coli

Study: Only one-third of patients receive living donor kidney transplant pre-emptively

New evidence highlights benefits and harms of using artificial mesh for surgical repair of vaginal prolapse

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

New pain management strategies key to maximizing patient outcomes after TKR procedures

TBX5 gene expression could play key role in congenital heart disease

Gut microbes influence severity of malaria

Benzodiazepine dementia risk refuted

Favourable safety, disease control for proton radiotherapy in paediatric medulloblastoma

Past experience alters the brain circuitry responsible for object recognition

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Findings may help states optimize tobacco cessation, cancer control programs

New study links sleep problems to poor academic performances among teens

Study shows association between traffic-related air pollution and dark spots on the skin

Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Study reveals association between DNA methylation and type 2 diabetes

University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

Effective treatments for knee instability may help reduce falls in older adults

Hallucinogens may have therapeutic potential against intimate partner violence

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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