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Companies with healthy workforces have competitive edge in stock market

A new study finds companies with healthy workforces appear to have a competitive edge in the stock market. The study compared the stock market performance of ten of the healthiest companies in South Africa to the market at large. Nine different investment scenarios were tested and, in all nine scenarios, the healthy companies outperformed the Johannesburg Stock Exchange All Share Index.

8 Feb 2016

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science.

8 Feb 2016

Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Cerapedics, a privately-held orthobiologics company, announced today results from a pivotal FDA Investigational Device Exemption (IDE) clinical trial for i-FACTOR Peptide Enhanced Bone Graft in anterior cervical discectomy and fusion (ACDF) procedures have been electronically published in the peer-reviewed journal Spine.

8 Feb 2016

Novel quantitative method may reduce or eliminate need for invasive biopsies

Scientists have identified a quantitative method to measure changes in biomarkers, which may reduce or eliminate the need for invasive biopsies. The method, described in the February 2016 issue of The FASEB Journal uses a novel chimera design of DNA and small DNA with a companion contrast agent to allow antibodies to cross cellular membranes.

8 Feb 2016

Transformational leadership could have positive effects on quality of patient care

A recent study shows that encouraging nurses to work towards a collective goal within a supportive milieu--a style of management called transformational leadership--can have positive effects on the quality of the care given to patients. It was also a predictor of nurses' intentions to stay on at their current healthcare facilities.

8 Feb 2016

Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

8 Feb 2016

New personalized DNA-based digital assay has potential to dramatically impact CML management

The outcomes of chronic myeloid leukemia (CML) have dramatically improved as the result of tyrosine kinase inhibitor (TKI) treatment. Use of a TKI regimen can lower the blood CML biomarker to levels imperceptible by current detection methods. For patients in "molecular remission," however, uncertainties remain regarding whether they will relapse or if treatment should be discontinued.

8 Feb 2016

Fortified dairy products increase serum vitamin D level in primary school children

Sufficient intake of fortified dairy products is of significant importance for the serum vitamin D level in primary school children, shows a new study from the University of Eastern Finland. Children who drink at least three glasses of milk per day had a higher serum vitamin D level than their peers who drink milk in lesser amounts.

7 Feb 2016

Stopping driving may lead to faster declines in physical and mental health function among older adults

Driving a car is a key factor in independent living and life satisfaction for older adults. In the U.S., driving is considered an important aspect of personal freedom and gives people a sense of control over their lives. Most adults continue to drive as they age--in fact, 81 percent of people aged 65 and older hold a driver's license in this country.

7 Feb 2016

Scientists identify potential marker for recurring HPV-positive oropharyngeal cancer

A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at The Johns Hopkins University.

7 Feb 2016

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.

7 Feb 2016

Vacations may lead to extra weight

A week's vacation may leave many adults with a heavier midsection--extra weight that can hang around even six weeks post-vacation.

7 Feb 2016

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes.

7 Feb 2016

Ambrisentan avoids sildenafil drug interaction in PAH patients

Sildenafil may be better given to pulmonary arterial hypertension patients in combination with ambrisentan than with bosentan, study findings suggest.

5 Feb 2016

$Falls, fractures may precede Parkinson’s disease by decades$

Falls, fractures may precede Parkinson’s disease by decades

People who later develop Parkinson’s disease have an increased tendency to fall and injure themselves, being at particular risk of hip fracture, a study shows.

5 Feb 2016

ADHD increases risk of becoming obese

With the incidence of obesity increasing steadily, much research has been undertaken to try and identify those people who are most likely to become obese so measures can be taken to avoid excessive weight gain, since it is easier to prevent than to reverse.

5 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

UTHealth researchers demonstrate new way to reduce preterm birth

Using nanoparticles to engineer a special drug, a team of researchers from McGovern Medical School at The University of Texas Health Science Center at Houston has demonstrated in pre-clinical trials a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies.

5 Feb 2016

Incidence and severity emerging CVD risk factors may differ between genders

The incidence and severity of both traditional and emerging cardiovascular disease (CVD) risk factors as well as the response to treatment may differ between genders. In this narrative review, several emerging CVD risk factors (i.e. inflammatory and haemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease) are discussed in the context of gender differences.

5 Feb 2016

Medical Research News

Companies with healthy workforces have competitive edge in stock market

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Novel quantitative method may reduce or eliminate need for invasive biopsies

Transformational leadership could have positive effects on quality of patient care

Aggression influences new nerve cell production in the brain

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

New personalized DNA-based digital assay has potential to dramatically impact CML management

Fortified dairy products increase serum vitamin D level in primary school children

Stopping driving may lead to faster declines in physical and mental health function among older adults

Scientists identify potential marker for recurring HPV-positive oropharyngeal cancer

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Vacations may lead to extra weight

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

Ambrisentan avoids sildenafil drug interaction in PAH patients

Falls, fractures may precede Parkinson’s disease by decades

ADHD increases risk of becoming obese

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

UTHealth researchers demonstrate new way to reduce preterm birth

Incidence and severity emerging CVD risk factors may differ between genders

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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