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Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

The National Institutes of Health has awarded $2.7 million to the Women's Medicine Collaborative to study the placenta and its function to determine whether changes in the placenta are linked to sleep abnormalities.

14 Aug 2015

Algorithm encompassing clinical and genetic factors predicts PD

Researchers have devised a model that distinguishes patients with Parkinson’s disease from those without the condition without relying on motor features.

14 Aug 2015

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

Allogeneic haematopoietic stem cell transplantation can be considered for chronic- and accelerated-phase chronic myeloid leukaemia patients with prior exposure to second-generation tyrosine kinase inhibitors, say Polish researchers.

14 Aug 2015

CML survey reveals patient TKI adherence, disease anxiety

Survey results suggest that chronic myeloid leukaemia patients using tyrosine kinase inhibitor therapy have good adherence to treatment but might benefit from counselling regarding their illness.

14 Aug 2015

TKI outcomes ‘unfavourable’ in young CML patients

Adolescent and young adult patients with chronic myeloid leukaemia may have an unfavourable outcome on tyrosine kinase inhibitor therapy compared with their older counterparts, suggests a study of Japanese patients.

14 Aug 2015

Risk for endophthalmitis no higher with Avastin, finds study

Eye injections of the drug Avastin, used to treat retinal diseases, bring no greater risk of endophthalmitis, a potentially blinding eye infection, than injections with the much more expensive drug Lucentis made by the same company, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their findings are published today in JAMA Ophthalmology.

14 Aug 2015

New system accurately and reliably captures patient experience with cancer drug side effects

In cancer clinical trials, symptom side effects patients experience, like nausea, are typically reported by doctors, and not directly by patients. Previous research has shown that doctors under-report these symptoms.

14 Aug 2015

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Many "medical foods" are designed to help manage patients with rare inborn errors of metabolism (IEMs), and can help prevent serious and life-threatening complications. However, such special foods may cause harm in some patients when their use is not carefully monitored and managed, according to a research team led by scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

14 Aug 2015

Centenary Institute researchers take lead on promising new class of drugs for melanoma treatment

Researchers at Sydney’s Centenary Institute have taken the lead on a promising new class of drugs that may prove to be highly effective for the treatment of certain cases of melanoma.

14 Aug 2015

Two new studies on eosinophilic granulomatosis with polyangiitis selected by Vasculitis Foundation

The Vasculitis Foundation is pleased to announce it has selected two new research studies on eosinophilic granulomatosis with polyangiitis (EGPA) /Churg Strauss for funding in the amount of $98,000.

14 Aug 2015

Dietitians skilled in integrative medical nutrition therapy could benefit patients

Integrative medicine is a quickly expanding field of health care that emphasizes nutrition as a key component. Dietitians and nutritionists have an opportunity to meet workforce demands by practicing dietetics and integrative medicine (DIM). A new JACN article, The Next Generation of Dietitians: Implementing Dietetics Education and Practice in Integrative Medicine describes a DIM education program and practicum. The review article appears in the Journal of the American College of Nutrition (JACN), official publication of the American College of Nutrition.

14 Aug 2015

Prion protein could play a role in depression

The discovery of antidepressant drugs in the 1950s led to the first biochemical hypothesis of depression, known as the monoamine hypothesis. This hypothesis proposes that an imbalance of certain brain chemicals is the key cause of depression.

14 Aug 2015

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

Troy Zars, Mirela Milescu, and Lorin Milescu, faculty members of the Division of Biological Sciences and the Interdisciplinary Neuroscience Program at the University of Missouri, have been awarded an Early Concept Grant for Exploratory Research (EAGER) from the National Science Foundation to expand the use of a temperature-activated protein switches in neurons. The new technology could lead to a better understanding of brain disorders in humans.

14 Aug 2015

National Cancer Institute's PRO-CTCAE accurate and reliable compared to other patient-reported measures

A multicenter study involving Mayo Clinic researchers has found that the National Cancer Institute's Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE), was accurate, reliable and responsive, compared to other, established patient-reported and clinical measures. The study is published today in the journal JAMA Oncology.

14 Aug 2015

Anti-smoking laws lead to decrease in stillbirths

Stillbirths have dropped by almost eight per cent in England since the smoking ban was introduced, research shows.

14 Aug 2015

MGH papers reveal the way anesthetics affect brains of older patients and children

Recent Massachusetts General Hospital (MGH) investigations into the neurobiology underlying the effects of general anesthesia have begun to reveal the ways different anesthetic agents alter specific aspects of the brain's electrical signals, reflected by EEG (electroencephalogram) signatures. While those studies have provided information that may lead to improved techniques for monitoring the consciousness of patients receiving general anesthesia, until now they have been conducted in relatively young adult patients.

14 Aug 2015

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

The mechanisms that allow the liver to repair and regenerate itself have long been a matter of debate. Now researchers at University of California, San Diego School of Medicine have discovered a population of liver cells that are better at regenerating liver tissue than ordinary liver cells, or hepatocytes.

14 Aug 2015

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Children born with the major congenital heart defect hypoplastic left heart syndrome (HLHS) often must undergo a series of corrective surgeries beginning at birth. While most have the standard three-stage Norwood procedure, a hybrid strategy has been introduced to offset some disadvantages associated with the Norwood surgeries. In a report in The Journal of Thoracic and Cardiovascular Surgery, investigators compare whether outcomes can be improved if an arterial shunt is used as a source of pulmonary blood flow rather than the more conventional venous shunt as part of the hybrid strategy of HLHS surgical reconstruction.

14 Aug 2015

Researchers examine potential effects of sex development disorders in children, adolescents

While it may not shock you to learn that children born with disorders of sex development (DSD) face challenges, Concordia University researchers have confirmed that these go far beyond the physical.

14 Aug 2015

Low-fat diets better than low-carb diets for weight loss, NIH study finds

In a recent study, restricting dietary fat led to body fat loss at a rate 68 percent higher than cutting the same number of carbohydrate calories when adults with obesity ate strictly controlled diets. Carb restriction lowered production of the fat-regulating hormone insulin and increased fat burning as expected, whereas fat restriction had no observed changes in insulin production or fat burning.

14 Aug 2015

Medical Research News

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

Algorithm encompassing clinical and genetic factors predicts PD

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

CML survey reveals patient TKI adherence, disease anxiety

TKI outcomes ‘unfavourable’ in young CML patients

Risk for endophthalmitis no higher with Avastin, finds study

New system accurately and reliably captures patient experience with cancer drug side effects

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Centenary Institute researchers take lead on promising new class of drugs for melanoma treatment

Two new studies on eosinophilic granulomatosis with polyangiitis selected by Vasculitis Foundation

Dietitians skilled in integrative medical nutrition therapy could benefit patients

Prion protein could play a role in depression

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

National Cancer Institute's PRO-CTCAE accurate and reliable compared to other patient-reported measures

Anti-smoking laws lead to decrease in stillbirths

MGH papers reveal the way anesthetics affect brains of older patients and children

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Researchers examine potential effects of sex development disorders in children, adolescents

Low-fat diets better than low-carb diets for weight loss, NIH study finds

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Automating research - solutions and best practices

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