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Inhibikase Therapeutics launches observational clinical study in patients who survived PML

Inhibikase Therapeutics, Inc. announces the launch of an observational clinical study in patients who contracted Progressive Multifocal Leukoencephalopathy (PML), the rare and often fatal brain infection that arises as an unintended side effect of some medications used for treatment of Multiple Sclerosis, Crohn's disease, Ulcerative Colitis and certain cancers of the blood and lymph.

13 Aug 2015

ADDF establishes Goodes Prize to recognize scientists in Alzheimer's drug discovery research

Thanks to the generosity of former Warner-Lambert CEO and Chairman Melvin R. Goodes and his family, the Alzheimer's Drug Discovery Foundation has established the only prize specifically recognizing scientists in Alzheimer's drug discovery research. Mr. Goodes—who has been open about his own Alzheimer's diagnosis—is an honorary member of the ADDF's Board of Governors.

13 Aug 2015

Swarm intelligence can help to improve breast cancer screening

Breast cancer is the most frequent type of cancer in women and currently accounts for 29% of all new cancer cases in the U.S. Wide-ranging mammography screening programs have been set up for early diagnosis. However, even if two physicians assess the x-rays, which is the usual procedure in Europe, this often leads to wrong decisions: about 20% of patients with cancer are diagnosed as being cancer-free, whereas about 20% of cancer-free patients are diagnosed with cancer.

13 Aug 2015

Scientists reveal how non-allergenic pollen mediators can increase allergic reactions

Scientists at Helmholtz Zentrum München and TU München discovered a new mechanism how non-allergenic pollen mediators can enhance allergic reactions. Especially the so-called B cells play a critical role in this process. The results were recently published in the Journal 'Allergy' and might lead to new approaches for therapies.

13 Aug 2015

Study finds that every second person dies in hospital

At home on the sofa, in a hospital bed, or in a care home: where a death takes place is always recorded on the death certificate. Until now, however, this information has never been collated and evaluated. In an Original Article in the current issue of Deutsches Ärzteblatt International (Dtsch Arztbl Int 112:496-504), Burkhard Dasch and his co-authors analyze for the first time the place of death records for Germany.

13 Aug 2015

CMU engineers awarded NSF grant to study neural variability in motor learning

When we move, we rarely move in the exact same way twice. The National Science Foundation has awarded Carnegie Mellon University Assistant Professor of Biomedical Engineering Steven Chase and Associate Professor of Electrical and Computer Engineering and Biomedical Engineering Byron Yu, and their long-time collaborator, University of Pittsburgh Associate Professor of Bioengineering Aaron Batista, an $869,000 grant to conduct basic research that will establish how variability in movement is encoded in the brain and how this variability contributes to learning and performance.

13 Aug 2015

Researchers reveal cellular origin of PIK3CA-induced breast tumors

In a study published in Nature, researchers lead by Cédric Blanpain, MD/PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, in collaboration with Pr Wayne Phillips, Australia and Pr Christos Sotiriou, Bordet Institute, Belgium, uncovered the cellular origin of PIK3CA-induced breast tumors and demonstrated that the cancer cell of origin controls tumor heterogeneity and is associated with different breast tumors types and clinical prognosis.

13 Aug 2015

Food ingredient formulators use different ways to enhance absorption, bioavailability of curcumin, turmeric

Few natural products have demonstrated the range of protective and therapeutic promise as have turmeric and its principal bioactive components, the curcuminoids.

13 Aug 2015

Children who consume higher ratio of PUFAs have more lean mass, less body fat

The results of a recent study show that children who report eating more polyunsaturated fatty acids (PUFAs), found in tree nuts, seeds and fatty fish, and consume a higher ratio of PUFA: saturated fatty acids (SFAs), have more lean body mass, lower percent body fat, and less intra-abdominal fat (belly fat).

13 Aug 2015

New study explains why statins are more beneficial than others in some cases

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease.

13 Aug 2015

Northwestern University researchers identify molecular difference in male and female brains

Male and female brains operate differently at a molecular level, a Northwestern University research team reports in a new study of a brain region involved in learning and memory, responses to stress and epilepsy.

13 Aug 2015

USF Health, FORCE receive $1.45 million from PCORI to advance and expand clinical research network

A team led by the University of South Florida Morsani College of Medicine and the leading national hereditary breast and ovarian cancer advocacy organization, FORCE (Facing Our Risk of Cancer Empowered) received a $1.45-million funding award for a three-year project from the Patient-Centered Outcomes Research Institute to continue to advance and expand the ABOUT Network as part of the second phase of PCORnet: the National Patient-Centered Clinical Research Network.

13 Aug 2015

FAU neuroscientist develops Quick Dementia Rating System comparable to gold standard clinical tests

Determining whether or not an individual has dementia and to what degree is a long and laborious process that can take an experienced professional such as a clinician about four to five hours to administer, interpret and score the test results. A leading neuroscientist at Florida Atlantic University has developed a way for a layperson to do this in three to five minutes with results that are comparable to the "gold standard" dementia tests used by clinicians today.

13 Aug 2015

Netrin1 protein acts as cellular "marriage broker"

Scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and the McGill University Health Centre, have made a breakthrough in understanding an important protein that appears to act as a kind of cellular "marriage broker."

13 Aug 2015

Researchers identify potential drug target to fight TB

The U.S. Food and Drug Administration recently approved the first new drug to fight tuberculosis (TB) in more than 40 years, but treatment still takes six months, 200 pills and leaves 40 percent of patients uncured. Thus, new targets are needed. Today in ACS Central Science, researchers report they have identified one such target -- a gene that allows the disease to camp out in human immune cells, and is thus essential for the organism's proliferation.

13 Aug 2015

FGF protein may play key role in breast and prostate cancer, shows research

Simply put, cancer is caused by mutations to genes within a cell that lead to abnormal cell growth. Finding out what causes that genetic mutation has been the holy grail of medical science for decades.

13 Aug 2015

Study suggests that eye movements during REM sleep responsible for resetting dream 'snapshots'

Rapid Eye Movement (REM) sleep, the period in which we experience vivid dreams, was discovered by scientists in the 1950s. Because REM sleep is associated with dreaming, on the one hand, and eye movement, on the other, it has been tempting to assume that each movement of the eye is associated with a specific dream image. But despite decades of intense research by leading international scientists, this intuitive hypothesis has remained unproven.

13 Aug 2015

Molecular on-off switch controls how mouse brain responds to vision loss

KU Leuven biologists have discovered a molecular on-off switch that controls how a mouse brain responds to vision loss.

13 Aug 2015

Higher-fit kids have significantly thinner gray matter, better mathematics achievement than their low-fit peers

A new study reveals that 9- and 10-year-old children who are aerobically fit tend to have significantly thinner gray matter than their "low-fit" peers. Thinning of the outermost layer of brain cells in the cerebrum is associated with better mathematics performance, researchers report in the journal PLOS ONE.

13 Aug 2015

First clinical trial to test use of retinal progenitor cells for treating retinitis pigmentosa begins

Participants are being enrolled in the first clinical trial that tests the use of retinal progenitor cells to treat retinitis pigmentosa, reported project director Dr. Henry Klassen of UCI's Gavin Herbert Eye Institute and Sue & Bill Gross Stem Cell Research Center. The product of stem cell research at UCI, these retinal progenitors are similar to stem cells in terms of potential regenerative properties, but they're specific to the retina.

13 Aug 2015

Medical Research News

Inhibikase Therapeutics launches observational clinical study in patients who survived PML

ADDF establishes Goodes Prize to recognize scientists in Alzheimer's drug discovery research

Swarm intelligence can help to improve breast cancer screening

Scientists reveal how non-allergenic pollen mediators can increase allergic reactions

Study finds that every second person dies in hospital

CMU engineers awarded NSF grant to study neural variability in motor learning

Researchers reveal cellular origin of PIK3CA-induced breast tumors

Food ingredient formulators use different ways to enhance absorption, bioavailability of curcumin, turmeric

Children who consume higher ratio of PUFAs have more lean mass, less body fat

New study explains why statins are more beneficial than others in some cases

Northwestern University researchers identify molecular difference in male and female brains

USF Health, FORCE receive $1.45 million from PCORI to advance and expand clinical research network

FAU neuroscientist develops Quick Dementia Rating System comparable to gold standard clinical tests

Netrin1 protein acts as cellular "marriage broker"

Researchers identify potential drug target to fight TB

FGF protein may play key role in breast and prostate cancer, shows research

Study suggests that eye movements during REM sleep responsible for resetting dream 'snapshots'

Molecular on-off switch controls how mouse brain responds to vision loss

Higher-fit kids have significantly thinner gray matter, better mathematics achievement than their low-fit peers

First clinical trial to test use of retinal progenitor cells for treating retinitis pigmentosa begins

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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