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Structural brain changes found in chemoradiation-treated glioblastoma patients

US researchers find evidence of marked and progressive brain atrophy during standard chemoradiation therapy in patients with glioblastoma.

5 Aug 2015

Hedgehog blockade promising in myeloid malignancies

Phase I trial results published in The Lancet Haematology show that the hedgehog signalling pathway antagonist PF-04449913 is tolerable and has activity in patients with haematological cancers.

5 Aug 2015

Poor relapse recovery heralds progressive MS

Multiple sclerosis patients with poor recovery from relapses develop the progressive form faster than those with good recovery, research shows.

5 Aug 2015

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Half of patients referred to a specialist centre with a diagnosis of chronic inflammatory demyelinating polyneuropathy do not actually have the condition, report researchers.

5 Aug 2015

Diaphragmatic pacing ’harmful’ in amyotrophic lateral sclerosis

Diaphragmatic pacing in conjunction with non-invasive ventilation is detrimental to patients with amyotrophic lateral sclerosis and respiratory insufficiency, show findings from a randomised controlled trial.

5 Aug 2015

TSRI study shows single injection of blebbistatin drug prevents methamphetamine relapse in animal models

Recovering addicts often grapple with the ghosts of their addiction—memories that tempt them to relapse even after rehabilitation and months, or even years, of drug-free living.

5 Aug 2015

In vitro testing provides proof of concept for osteopathic manipulative therapy

In vitro studies of the cellular effects of modeled osteopathic manipulative therapy (OMT) provide proof of concept for the manual techniques practiced by doctors of osteopathic medicine (DOs), according to researchers from the University of Arizona College of Medicine - Phoenix.

5 Aug 2015

Children increase parents’ risk for viral infection

The BIG LoVE (Utah Better Identification of Germs-Longitudinal Viral Epidemiology) study, led by scientists at the University of Utah School of Medicine, finds that each bundle of joy puts the entire household at increased risk for infection with viruses that cause colds, flu, and other respiratory illnesses.

5 Aug 2015

Circadian factors, host gender could help understand microbiome and its effect on inflammatory bowel disease

By now, the old saw, "You are what you eat," has been well-used in describing the microbiome. However axiomatic that phrase may be, a new study has also found that who and when that consumption is done can affect microbiome make-up.

5 Aug 2015

New research could help understand how ongoing behavior influences visual perception

Our brains are constantly barraged with sensory information, but have an amazing ability to filter out just what they need to understand what's going on around us. For instance, if you stand perfectly still in a room, and that room rotates around you, it's terrifying.

5 Aug 2015

Despite high job demands, mere experience of being on-call promotes work fatigue

With the growing demands of consumerism and the need to assist customers on the clock, today's employees are working anything but nine to five.

5 Aug 2015

Researchers find CD163 protein limits muscle repair after ischemic injury

Researchers have identified a protein produced by white blood cells that puts the brakes on muscle repair after injury. By removing the protein CD163 from mice, scientists at Emory University School of Medicine could boost muscle repair and recovery of blood flow after ischemic injury (damage caused by restriction of blood flow).

5 Aug 2015

Certain genes exposed to harsh environmental factors can increase diabetes risk

Arsenic, which can be present in ground water, modifies an enzyme that alters the secretion of insulin in the pancreas. Physicians, usually, show type II diabetes as a consequence of an exaggerated food intake and lack of exercise; however, there are about 50 genes that cause changes in the DNA, known as polymorphisms, that when combined with harsh environmental factors are at increased risk of developing the disease, mentioned PhD Marta Ostrosky Wegman, director of the Institute for Biomedical Research the National University of Mexico (UNAM).

5 Aug 2015

Sleeping in lateral position may effectively remove brain waste, say Stony Brook researchers

Sleeping in the lateral, or side position, as compared to sleeping on one's back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer's, Parkinson's and other neurological diseases, according to researchers at Stony Brook University.

5 Aug 2015

Cancer survival in England remains lower compared to other countries with similar healthcare systems

Cancer survival in England remains lower than countries with similar healthcare systems, according to a new Cancer Research UK funded study published in the British Journal of Cancer today (Wednesday).

5 Aug 2015

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Joslin scientists have advanced understanding of how the cellular repair process is impaired in type 1 diabetes, which can cause cell death and lead to complications. The findings appear in the August issue of Cell Metabolism.

5 Aug 2015

Aging adults who follow MIND diet can delay cognitive decline

While cognitive abilities naturally diminish as part of the normal aging process, it may be possible to take a bite out of this expected decline.

5 Aug 2015

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

The Cancer Research Institute, a nonprofit organization dedicated to fueling the discovery and development of immunotherapies for all forms of cancer, announced that it has committed more than $29.3 million in new funds to accelerate cancer immunology research and cancer immunotherapy clinical development in the United States, Australia, Canada, France, Sweden, Switzerland, and The Netherlands.

5 Aug 2015

Children exposed to indoor cooking fire at greater risk for severe trachoma

Children who sleep in unventilated rooms with cooking fires are at greater risk for severe trachoma, a leading cause of preventable blindness in developing countries, according to the findings of a recent study conducted in Tanzania. The study was supported by the National Eye Institute, part of the National Institutes of Health.

5 Aug 2015

Swedish study reveals combined effects of smoking and early menopause on overall mortality

Women may now have yet another reason to quit smoking given the results of a new study that is being reported online today in Menopause, the journal of The North American Menopause Society. The Swedish study involving 25,474 women is the first to quantify the combined effects of smoking and age at menopause on overall mortality in terms of survival time by investigating the role of smoking as a possible effect modifier.

5 Aug 2015

Medical Research News

Structural brain changes found in chemoradiation-treated glioblastoma patients

Hedgehog blockade promising in myeloid malignancies

Poor relapse recovery heralds progressive MS

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Diaphragmatic pacing ’harmful’ in amyotrophic lateral sclerosis

TSRI study shows single injection of blebbistatin drug prevents methamphetamine relapse in animal models

In vitro testing provides proof of concept for osteopathic manipulative therapy

Children increase parents’ risk for viral infection

Circadian factors, host gender could help understand microbiome and its effect on inflammatory bowel disease

New research could help understand how ongoing behavior influences visual perception

Despite high job demands, mere experience of being on-call promotes work fatigue

Researchers find CD163 protein limits muscle repair after ischemic injury

Certain genes exposed to harsh environmental factors can increase diabetes risk

Sleeping in lateral position may effectively remove brain waste, say Stony Brook researchers

Cancer survival in England remains lower compared to other countries with similar healthcare systems

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Aging adults who follow MIND diet can delay cognitive decline

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

Children exposed to indoor cooking fire at greater risk for severe trachoma

Swedish study reveals combined effects of smoking and early menopause on overall mortality

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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