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Postponing chemotherapy may increase risk of death for triple-negative breast cancer patients

Postponing the start of adjuvant chemotherapy for more than 90 days following surgery may significantly increase risk of death for breast cancer patients, particularly those with triple-negative breast cancer (TNBC), according to a new study from The University of Texas MD Anderson Cancer Center.

11 Dec 2015

Cancer drug can neutralize toxic RNA that causes myotonic dystrophy

A group of researchers has shown for the first time in cells and in a mouse model that a drug used to treat cancer can neutralize the toxic RNA that causes the prolonged muscle contractions and other symptoms of myotonic dystrophy type 1, the most common form of adult-onset muscular dystrophy.

11 Dec 2015

Shank3 gene linked to both autism and schizophrenia

Although it is known that psychiatric disorders have a strong genetic component, untangling the web of genes contributing to each disease is a daunting task. Scientists have found hundreds of genes that are mutated in patients with disorders such as autism, but each patient usually has only a handful of these variations.

10 Dec 2015

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

The pan-European TETRA consortium, led by Videregen Limited, has been awarded EUR 6.8 million under the Horizon 2020 programme for a pivotal Phase II clinical trial of the company's tissue engineered replacement trachea.

10 Dec 2015

More California college students seeking mental health treatment, new RAND study shows

The proportion of California public university and college students receiving treatment for mental health issues increased more than 10 percent in the final year of a statewide prevention and early intervention program, according to a new RAND Corporation study.

10 Dec 2015

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Circuit Therapeutics today announced that it has been awarded a 2.7 million dollar contract from the Defense Advanced Research Projects Agency to pursue optogenetic therapies for peripheral nervous system indications. The award, part of DARPA's Electrical Prescriptions (ElectRX) program, will enable Circuit to pursue research and development projects related to its treatment for neuropathic pain.

10 Dec 2015

Too much sleep, too much sitting may shorten life

Sleeping more than nine hours a night, and sitting too much during the day could be a hazardous combination, particularly when added to a lack of exercise, according to new findings to emerge from the Sax Institute's 45 and Up Study.

10 Dec 2015

Happiness has no direct effect on mortality, say experts

A study of women in the UK has shown that there is no evidence to suggest that happiness has any direct effect on reducing mortality, despite the widespread belief that being unhappy can directly cause ill health.

10 Dec 2015

Caregiver-implemented singing beneficial in early stages of dementia

Researchers led by Dr. Teppo Särkämö at University of Helsinki, Finland have revealed that caregiver-implemented musical leisure activities, particularly singing, are cognitively and emotionally beneficial especially in the early stages of dementia. The findings could help improve dementia care and better target the use of music in different stages of dementia.

10 Dec 2015

Understanding different forms of MS may lead to better therapeutic approaches, treatments

Understanding the boundaries between relapsing and progressive multiple sclerosis is essential to finding better therapeutic approaches and treatments for patients living with MS, according to Jerry S. Wolinsky, M.D., of the University of Texas in Houston.

10 Dec 2015

New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University, Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

10 Dec 2015

Human heart can fully recover after massive damage

The scientists report the case of a newborn that had suffered a massive heart attack in the first hours of life. It was caused by a blockage in a vital coronary vessel. "The baby's heart was severely damaged. Astonishingly, the baby recovered very quickly," said Bernhard Haubner, a cardiologist and researcher, and his colleague, Johanna Schneider, in an article just published in the journal "Circulation Research".

10 Dec 2015

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) differ in their efficacy and safety profiles, according to new research by the University of Leicester.

10 Dec 2015

Study reveals molecular function of protein essential for replication of H5N1 flu virus

An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza virus.

10 Dec 2015

New research aims to help people suffering from poor blood circulation, reduce aching pains

The University of Salford is looking for volunteers to take part in a new research study that aims to help people who suffer from poor blood circulation to walk without pain.

10 Dec 2015

Researchers identify brain processes in mice that shape different sensory perceptions

Scientists have long known that when sounds are faint or objects are seen through fog in the distance, repetition of these weak or ambiguous sensory “inputs” can result in different perceptions inside the same brain.

10 Dec 2015

U of I study suggests link between instability and risky sexual behaviors among college students

A University of Illinois study suggests a significant link between instability in the lives of college-age young adults and the likelihood that they will engage in risky sex.

10 Dec 2015

Monoclonal antibody reduces relapse rate by 18% in postmenopausal, HR-positive breast cancer patients

Giving a monoclonal antibody (denosumab) as adjuvant therapy with aromatase inhibitors in postmenopausal, hormone-receptor-positive breast cancer patients reduces the relapse rate by 18%. This is the central finding of the ABCSG 18 breast cancer study regarding disease-free survival.

10 Dec 2015

Left behind rural children in China at increased risk for obesity

Some 61 million rural children left behind by parents moving to China's booming urban centres are at risk from increased fat and reduced protein in their diets, research from The University of Manchester, published in Public Health Nutrition suggests.

10 Dec 2015

New study finds relationship between socioeconomic factors and distribution of anesthesia providers

A new study suggests that Certified Registered Nurse Anesthetists (CRNAs) are the main anesthesia professionals ensuring patient access to critical anesthesia care in lower-income areas where the populations are more likely to be uninsured, unemployed and/or Medicaid eligible.

10 Dec 2015

Medical Research News

Postponing chemotherapy may increase risk of death for triple-negative breast cancer patients

Cancer drug can neutralize toxic RNA that causes myotonic dystrophy

Shank3 gene linked to both autism and schizophrenia

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

More California college students seeking mental health treatment, new RAND study shows

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Too much sleep, too much sitting may shorten life

Happiness has no direct effect on mortality, say experts

Caregiver-implemented singing beneficial in early stages of dementia

Understanding different forms of MS may lead to better therapeutic approaches, treatments

New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Human heart can fully recover after massive damage

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Study reveals molecular function of protein essential for replication of H5N1 flu virus

New research aims to help people suffering from poor blood circulation, reduce aching pains

Researchers identify brain processes in mice that shape different sensory perceptions

U of I study suggests link between instability and risky sexual behaviors among college students

Monoclonal antibody reduces relapse rate by 18% in postmenopausal, HR-positive breast cancer patients

Left behind rural children in China at increased risk for obesity

New study finds relationship between socioeconomic factors and distribution of anesthesia providers

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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