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Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Researchers recommend performing echocardiography at rest and during exercise to screen for pulmonary arterial hypertension in patients with systemic sclerosis.

15 Jul 2015

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

Researchers at the Centenary Institute in Sydney have uncovered new information about an enzyme called DPP9 that they believe to be a potential therapeutic target for limiting tumour growth and its ability to spread to and in the liver.

15 Jul 2015

UK investment lacking for pneumonia research

UK investment in pneumonia research is lacking when compared to spending on influenza and tuberculosis, according to a new study by the University of Southampton and University College London.

15 Jul 2015

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

Scientists have discovered a new variant of streptococcal bacteria that has contributed to a rise in disease cases in the UK over the last 17 years.

15 Jul 2015

Pioneering Southampton research investigates health impacts of spaceflight

Pioneering research from the University of Southampton into the health impacts of spaceflight has been identified as a possible experiment to be conducted by British astronaut Tim Peake on his maiden voyage to the International Space Station later this year.

15 Jul 2015

New study shows high-fat diet can cause impairments in functioning of mesolimbic dopamine system

High-fat feeding can cause impairments in the functioning of the mesolimbic dopamine system, says Stephanie Fulton of the University of Montreal and the CHUM Research Centre. This system is a critical brain pathway controlling motivation. Fulton's findings, published today in Neuropsychopharmacology, may have great health implications.

15 Jul 2015

Cassiopea selects DATATRAK platform for significant global study

DATATRAK International, Inc., the leader in developing cloud-based, unified dClinical technologies and delivering related services for the clinical trials industry, today announced that Cassiopea S.p.A., the newly IPO'd former subsidiary of longtime partner Cosmo Pharmaceuticals SA has selected DATATRAK for a significant global study.

15 Jul 2015

Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Among women with a family history of breast cancer, those diagnosed with breast cancer gained weight at a greater rate compared with cancer-free women of the same age and menopausal status.

15 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

Women with low levels of anti-stress hormone at increased risk of getting breast cancer

A new study from Lund University in Sweden shows that women with low levels of an anti-stress hormone have an increased risk of getting breast cancer. The study is the first of its kind on humans and confirms previous similar observations from animal experiments.

15 Jul 2015

New review article explains link between PTSD and increased cardiovascular disease risk

A growing number of patient studies show that people who suffered post-traumatic stress disorder (PTSD) are at a higher risk of developing cardiovascular diseases, including stroke and heart attack. A new review article in American Journal of Physiology—Regulatory, Integrative and Comparative Physiology examines the recent scientific literature to explain how the two are linked.

15 Jul 2015

Diabetes drug metformin can also treat portal hypertension

The diabetes drug metformin continues to expand beyond its treatment for type 2 diabetes. In addition to its potential use in treating age-related health problems, metformin can treat portal hypertension—high blood pressure in the liver resulting from cirrhosis, according to a new study in American Journal of Physiology—Gastrointestinal and Liver Physiology.

15 Jul 2015

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

Chunying Li, Ph.D., assistant professor in the Wayne State University School of Medicine's Department of Biochemistry and Molecular Biology, has secured his first R01 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to study the role and mechanism of the chemokine receptor CXCR2 in regulating new blood vessel formation, the so-called angiogenesis.

15 Jul 2015

New study highlights burden of community-acquired pneumonia hospitalizations among U.S. adults

Viruses, not bacteria, are the most commonly detected respiratory pathogens in U.S. adults hospitalized with pneumonia, according to a New England Journal of Medicine study released today and conducted by researchers at Centers for Disease Control and Prevention and hospitals in Chicago and Nashville, including Vanderbilt University Medical Center.

15 Jul 2015

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer devastating side effects for years? New UCLA/USC research suggests that damage to the fatty sheaths around the brain's nerve fibers--not injury severity-- may explain the difference. Published in the July 15 edition of the Journal of Neuroscience, the finding identifies possible biomarkers that physicians could use to predict higher-risk patients who require closer monitoring.

15 Jul 2015

Lower-intensity summerMAX treatment equally effective as high-intensity for children with HFASD

Researchers at the Institute for Autism Research at Canisius College have found that reducing the intensity of their comprehensive summer treatment (summerMAX) yielded improvements for high-functioning children with autism spectrum disorder (HFASD) that were comparable to the original high-intensity program.

15 Jul 2015

Study highlights how KLF15 protein affects availability of nutrients in the body

Case Western Reserve researchers already demonstrated that a single protein plays a pivotal role in the use of nutrients by major organs that allow for the burning of fat during exercise or regulating the heart's contractile and electrical activity. Now they have found a new benefit of Kruppel-like Factor 15 (KLF15) — keeping the body in metabolic balance.

15 Jul 2015

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA.

15 Jul 2015

Agilent and BTI collaborate to address a critical need in biopharmaceutical industry

The collaboration will address a gap in analytical tests and standards applied for drugs based on glycoproteins, which now form the majority of approved biopharmaceutical drugs. Current analytical methods for characterizing glycans are time-consuming and difficult to deploy in commercial environments. They are also limited in their ability to detect and analyze minor glycan species.

15 Jul 2015

Medical Research News

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

UK investment lacking for pneumonia research

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

Pioneering Southampton research investigates health impacts of spaceflight

New study shows high-fat diet can cause impairments in functioning of mesolimbic dopamine system

Cassiopea selects DATATRAK platform for significant global study

Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

Women with low levels of anti-stress hormone at increased risk of getting breast cancer

New review article explains link between PTSD and increased cardiovascular disease risk

Diabetes drug metformin can also treat portal hypertension

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

New study highlights burden of community-acquired pneumonia hospitalizations among U.S. adults

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

Lower-intensity summerMAX treatment equally effective as high-intensity for children with HFASD

Study highlights how KLF15 protein affects availability of nutrients in the body

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Agilent and BTI collaborate to address a critical need in biopharmaceutical industry

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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