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Some antibiotics may make MRSA more harmful

Treating MRSA with certain first-line antibiotics can actually make MRSA skin infections worse, according to a study published in Cell Host & Microbe.

12 Nov 2015

UCSF-led researchers map out melanoma's genetic trajectories

An international team of scientists led by UC San Francisco researchers has mapped out the genetic trajectories taken by melanoma as it evolves from early skin lesions, known as precursors, to malignant skin cancer, which can be lethal when it invades other tissues in the body.

12 Nov 2015

Shared decision making between doctors and patients useful in fight against antibiotic resistance

A new Cochrane Review published today shows that when doctors and patients are encouraged to discuss the need for prescribing antibiotics for acute respiratory infections jointly, fewer are prescribed. This may be useful in the fight against antibiotic resistance.

12 Nov 2015

Doctors and relatives often take patients' written wishes in different ways

If a patient is no longer able to communicate personally how he or she would like to be treated, doctors and relatives consult an advance directive, if one is available. However, doctors and relatives often interpret patients' written wishes in different ways, as Nadja Leder et al. establish in their original article in the current issue of Deutsches Ärzteblatt International (Dtsch Arztbl Int 112: 723-9).

12 Nov 2015

HEAL Project aims to regenerate human knees and limbs within 15 years

On Veteran's Day the University of Connecticut announced the launch of its new grand research challenge: regeneration of a human knee within 7 years, and an entire limb within 15 years.

12 Nov 2015

Financial incentives offered to help pregnant women quit smoking are highly cost-effective: Study

The scientific journal Addiction has today published the first cost-effectiveness analysis of financial incentives to help pregnant women stop smoking. The report found that financial incentives are highly cost-effective, with an incremental cost-effectiveness ratio (ICER) of £482 ($734) per quality-adjusted life year (QALY), which is well below recommended thresholds in high income countries.

12 Nov 2015

Young offenders face a greater risk for early death, finds new study

In the U.S. the chances of being arrested are one in three by age 23. Youth offenders face a greater risk for early death than the rest of the population; according to a new study published in the American Journal of Preventive Medicine, that risk increases as a young person becomes more involved in the judicial system. The more serious and prolonged a youth's interaction with the justice system becomes, the more likely he or she is to die prematurely.

12 Nov 2015

Meta-analysis supports that intake of tree nuts lowers risk of cardiovascular disease

In a study published yesterday in the American Journal of Clinical Nutrition*, researchers performed a systematic review and meta-analysis of controlled trials to investigate the effects of tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) on blood lipids, lipoproteins, blood pressure and inflammation in adults 18 years and older without prevalent cardiovascular disease (CVD).

12 Nov 2015

Angina in women linked with abnormal heart blood flow

Chest pain in female-pattern heart disease is linked with abnormal heart blood flow, demonstrated with a drug commonly used to alleviate chest pain patients with coronary artery disease, which was found to be ineffective in patients with moderate female-pattern heart disease, but may offer some relief for sicker patients, a new Cedars-Sinai Heart Institute study shows.

12 Nov 2015

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Promising new approaches to treating cancer were reported during a recent meeting of researchers from Loyola University Chicago and the University of Notre Dame.

12 Nov 2015

Bariatric surgery improves weight, metabolic health and quality of life in adolescents after 3 years

The results of a new study to be published November 6, 2015 in The New England Journal of Medicine to coincide with presentation at The Obesity Society Annual meeting in Los Angeles, California show that three years after undergoing bariatric surgery, adolescents experienced major improvements in their weight, metabolic health, and quality of life.

12 Nov 2015

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Researchers have taken a significant step forward in developing gene therapy against a fatal neurodegenerative disease that strikes children. By delivering a working version of a gene to produce a key enzyme that is lacking in Batten disease, the scientists delayed symptoms and extended lifespan in dogs with a comparable disease.

12 Nov 2015

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Learning if a lung cancer patient has genetic mutations can help oncologists determine the best approach to treatment. There are four gene mutations (KRAS, TP53, STK11, and EGFR) that most commonly occur in lung cancer; however, there are limited effective therapies to target these mutations. With this in mind, Moffitt Cancer Center performed an extensive genetic analysis of lung cancer specimens to unravel how mutations in the two of those genes (TP53 and STK11) contribute to the biology of lung cancer and patient outcomes.

12 Nov 2015

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight. A recent NIH study, for example, found that adults who are obese or overweight at midlife may be at risk for earlier onset of Alzheimer's disease.

12 Nov 2015

Brain scans may predict possibility of recovering from coma

Brain scans of people in a coma may help predict who will regain consciousness, according to a study published in the November 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. The study looked at connections between areas of the brain that play a role in regulating consciousness.

12 Nov 2015

Research brings scientists one step closer to developing human-like artificial intelligence

Making a computer that learns and remembers like a human brain is a daunting challenge. The complex organ has 86 billion neurons and trillions of connections -- or synapses -- that can grow stronger or weaker over time. But now scientists report in ACS' journal Nano Letters the development of a first-of-its-kind synthetic synapse that mimics the plasticity of the real thing, bringing us one step closer to human-like artificial intelligence.

12 Nov 2015

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

A University of South Florida Center for Global Health & Infectious Diseases Research team has demonstrated a new screening model to classify antimalarial drugs and to identify drug targets for the most lethal strain of malaria, Plasmodium falciparum.

12 Nov 2015

Researchers reveal how charged gold nanoparticles influence structure of DNA and RNA

Researchers at North Carolina State University have used computational modelling to shed light on precisely how charged gold nanoparticles influence the structure of DNA and RNA - which may lead to new techniques for manipulating these genetic materials.

12 Nov 2015

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

Patients who develop ovarian cancer appear to have better outcomes if they have a history of oral contraceptive use, according to a study by Mayo Clinic researchers published in the current issue of the journal BMC Cancer.

12 Nov 2015

ApoE4-carrying men with Alzheimer's disease at risk of brain bleeds

A common genetic variation, ApoE4, linked to Alzheimer's disease greatly raises the likelihood of tiny brain bleeds in some men, scientists have found.

12 Nov 2015

Medical Research News

Some antibiotics may make MRSA more harmful

UCSF-led researchers map out melanoma's genetic trajectories

Shared decision making between doctors and patients useful in fight against antibiotic resistance

Doctors and relatives often take patients' written wishes in different ways

HEAL Project aims to regenerate human knees and limbs within 15 years

Financial incentives offered to help pregnant women quit smoking are highly cost-effective: Study

Young offenders face a greater risk for early death, finds new study

Meta-analysis supports that intake of tree nuts lowers risk of cardiovascular disease

Angina in women linked with abnormal heart blood flow

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Bariatric surgery improves weight, metabolic health and quality of life in adolescents after 3 years

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Brain scans may predict possibility of recovering from coma

Research brings scientists one step closer to developing human-like artificial intelligence

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

Researchers reveal how charged gold nanoparticles influence structure of DNA and RNA

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

ApoE4-carrying men with Alzheimer's disease at risk of brain bleeds

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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