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BUSM researchers explore how do not resuscitate orders affect hospital rankings for pneumonia

Researchers from Boston University School of Medicine examined how hospital differences in patient preferences for life-sustaining treatments (do not resuscitate, or DNR, orders) affected hospital rankings for pneumonia.

16 Dec 2015

Molecular signatures can predict flu vaccine responses in young and old

What factors inhibit strong responses to seasonal flu vaccines in the elderly? Why do anti-flu antibodies last longer after vaccination in some people? Answers are emerging from an Emory University-based systems biology analysis of blood samples from more than 400 volunteers who received seasonal flu vaccines. Bali Pulendran, PhD, led a team of researchers who tracked patterns of gene expression, known as molecular signatures, of strong immune responses in volunteers' blood across five consecutive seasons from 2007 to 2011.

16 Dec 2015

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015

U of T researchers find another clue in understanding the cause of MS

Researchers at the University of Toronto have found another clue in understanding the cause of what drives Multiple Sclerosis (MS) disease. Their findings were published today in Immunity.

16 Dec 2015

Innovative brain imaging study reveals why ToM deficiencies present in children with ASD

The holidays can be difficult for children with autism spectrum disorder (ASD), particularly because of new or different social situations. One reason scientists believe ASD causes impairment in social interactions is due to an inability to effectively infer other's thoughts and feelings through "theory of mind," or ToM -- the ability to understand the mental states of others and oneself.

16 Dec 2015

Shingles vaccine can help protect elderly patients with end-stage renal disease

Elderly patients with end-stage renal disease (ESRD) who received the shingles vaccine were half as likely to develop shingles compared to those who were not vaccinated. The new study from Kaiser Permanente, published in Clinical Infectious Diseases, also found the best protection against shingles was achieved when patients received the vaccination shortly after beginning dialysis.

16 Dec 2015

UW-Madison scientist creates serotonin neurons from stem cells

Su-Chun Zhang, a pioneer in developing neurons from stem cells at the University of Wisconsin-Madison, has created a specialized nerve cell that makes serotonin, a signaling chemical with a broad role in the brain.

16 Dec 2015

Columbia Engineering professor wins grant to study tendon-to-bone integration for rotator cuff repair

Helen H. Lu, professor of biomedical engineering at Columbia Engineering, has won a three-year $1.125 million Translational Research Award grant from the Department of Defense's Congressionally Directed Medical Research Programs for her research on tendon-to-bone integration for rotator cuff repair.

16 Dec 2015

Can Nanostructured Microelectrodes be Used to Analyze Biomarkers? An Interview with Dr Shana Kelley

Electrochemical methods are appealing because simple and inexpensive instrumentation can be used to make highly sensitive measurements. However, it has been quite difficult to realize clinically-relevant levels of sensitivity using electrochemistry in highly complex, real-world samples.

From Pittcon 15 Dec 2015

Discovery could pave way for targeted therapies to treat penile cancer

Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.

15 Dec 2015

VCU Massey Cancer Center scientists reveal signaling process that leads to excessive growth of cancer

The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and now a recent study by VCU Massey Cancer Center scientist Richard Moran, Ph.D., explains why.

15 Dec 2015

Childhood family breakup can affect girls more than boys

A childhood family breakup can have long-term negative consequences for the children. Recent University of Illinois research looks at overall health, depression, and smoking as a health-related behavior and finds that, for girls, all three are worse.

15 Dec 2015

UCLA-developed resilience program helps military families cope with combat-related injuries

Across the U.S., families of troops serving in Iraq, Afghanistan, Syria, Uganda and other hot spots are emailing photos of their holiday feasts to their loved ones overseas -- and asking them to respond with pictures of their own holiday celebrations.

15 Dec 2015

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

Researchers at Karolinska Institutet, and the Sahlgrenska Academy at Gothenburg University in Sweden have identified a gene variant linked to psychotic symptoms and cognitive impairment in people with bipolar disorder. The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

15 Dec 2015

African American men with clinical chronic prostatitis have lower risk of prostate cancer

According to a new study, African American men with clinical chronic prostatitis have a significantly lower risk of prostate cancer.

15 Dec 2015

Honeywell acquires Sigma-Aldrich's laboratory research chemicals business

Honeywell today announced that it has completed the acquisition of the Seelze, Germany-based laboratory research chemicals business from Sigma-Aldrich, broadening Honeywell's offerings for high-purity solutions for drug discovery, medical diagnostic testing and other laboratory applications.

15 Dec 2015

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

Researchers at Penn State College of Medicine, working with Chinese and American colleagues, have discovered a novel way to enhance and restore cancer suppressor activity in B-cell acute lymphoblastic leukemia, resulting in better outcomes in a pre-clinical model of the disease. The finding could pave the way for a new class of drugs for this and other forms of leukemia.

15 Dec 2015

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

More than a quarter of the 30 million people with diabetes in the United States depend on daily injections of insulin to maintain their blood glucose levels in a healthy range. Scientists are investigating many techniques to help treat or potentially even cure many of these patients by increasing the body's own insulin-producing pancreatic "beta" cells.

15 Dec 2015

Experimental drugs that modify cell metabolism also halt tumor growth

Experimental drugs that alter cell metabolism also halted tumor growth and extended survival in mice with cancers linked to changes in the same gene, according to a new study led by researchers at NYU Langone Medical Center, its Laura and Isaac Perlmutter Cancer Center and Massachusetts General Hospital.

15 Dec 2015

Using antidepressants during pregnancy greatly increases autism risk

Using antidepressants during pregnancy greatly increases the risk of autism, Professor Anick Bérard of the University of Montreal and its affiliated CHU Sainte-Justine children's hospital revealed today. Prof. Bérard, an internationally renowned expert in the fields of pharmaceutical safety during pregnancy, came to her conclusions after reviewing data covering 145,456 pregnancies.

15 Dec 2015

Medical Research News

BUSM researchers explore how do not resuscitate orders affect hospital rankings for pneumonia

Molecular signatures can predict flu vaccine responses in young and old

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

U of T researchers find another clue in understanding the cause of MS

Innovative brain imaging study reveals why ToM deficiencies present in children with ASD

Shingles vaccine can help protect elderly patients with end-stage renal disease

UW-Madison scientist creates serotonin neurons from stem cells

Columbia Engineering professor wins grant to study tendon-to-bone integration for rotator cuff repair

Can Nanostructured Microelectrodes be Used to Analyze Biomarkers? An Interview with Dr Shana Kelley

Discovery could pave way for targeted therapies to treat penile cancer

VCU Massey Cancer Center scientists reveal signaling process that leads to excessive growth of cancer

Childhood family breakup can affect girls more than boys

UCLA-developed resilience program helps military families cope with combat-related injuries

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

African American men with clinical chronic prostatitis have lower risk of prostate cancer

Honeywell acquires Sigma-Aldrich's laboratory research chemicals business

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

Experimental drugs that modify cell metabolism also halt tumor growth

Using antidepressants during pregnancy greatly increases autism risk

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