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Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Resverlogix Corp. is pleased to announce that Dr. Norman Wong, chief scientific officer of Resverlogix Corp. presented new data at the European Society of Cardiology (ESC) Congress 2015 in a poster presentation titled: "RVX-208, an orally active BET inhibitor, lowers CVD risk by activities beyond raising ApoA-I/HDL."

31 Aug 2015

Gene ZSCAN4 may help treat Down syndrome

For people with Down syndrome, news from Elixirgen, LLC may brighten their day. The biotechnology company, located in the Science + Technology Park at Johns Hopkins, has outlined one of the best potential therapies yet for people with Down syndrome and other chromosome disorders in a paper entitled, "Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures," published in the journal DNA Research.

31 Aug 2015

Additional electrical isolation of left atrial appendage could improve freedom from AF

In patients with long-standing persistent atrial fibrillation (AF) despite standard treatment, additional electrical isolation of an area called the left atrial appendage (LAA) can improve freedom from AF without increasing complications, results of the BELIEF study show.

31 Aug 2015

Study: Depressed patients three times more likely to experience frequent chest pain

Depressed patients have more frequent chest pain even in the absence of coronary artery disease, according to results from the Emory Cardiovascular Biobank presented at ESC Congress today by Dr Salim Hayek, a cardiologist at Emory University School of Medicine in Atlanta, Georgia, US.

31 Aug 2015

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Prolonged television watchers have a higher risk of fatal pulmonary embolism, a condition associated with long haul flights, reveals research presented at ESC Congress today by Mr Toru Shirakawa, public health research fellow in the Department of Social Medicine at Osaka University in Japan.

31 Aug 2015

Leadless cardiac pacemakers could overcome complications of conventional transvenous pacemakers

A leadless cardiac pacemaker showed "good safety and reliable function" during the initial six months of follow-up in the LEADLESS II study, investigators reported during a Hot Line presentation at the ESC congress 2015.

31 Aug 2015

TECOS analysis shows sitagliptin safe and effective in patients with type-2 diabetes, cardiovascular disease

Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug sitagliptin without an increased risk of cardiovascular complications - even if they have a history of heart failure - a new analysis of the TECOS (Trial Evaluating Cardiovascular Outcomes with Sitagliptin) study shows.

31 Aug 2015

Depression, blood pressure predict harmful vascular events in patients with heart disease, diabetes or stroke

Depressive symptoms and extremes of blood pressure predict the highest rates of harmful vascular events in patients with existing heart disease, diabetes or stroke, according to research presented at ESC Congress today by Dr Bhautesh Jani, clinical academic fellow in the Institute of Health and Wellbeing, University of Glasgow, UK.

31 Aug 2015

Study shows food craving may be hard-wired into the brain of overweight patients

An international group of researchers have found that food craving activates different brain networks between obese and normal weight patients.

31 Aug 2015

Stroke prevention strategies in elderly should focus on multiple risk factors

The impact of atrial fibrillation on ischaemic stroke risk in elderly patients is eliminated with multiple risk factors, according to an 11 year study in more than 425 000 patients presented at ESC Congress today.

31 Aug 2015

Depression and self-harm risk increased among goth teenagers

New research published in the Lancet indicates that young people who consider themselves to be part of the goth subculture might be at increased risk of depression and self-harm.

31 Aug 2015

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

When it comes to treating high blood pressure, not all anti-hypertensive medications are equal, and results of the ATTEMPT-CVD trial suggest that telmisartan, an angiotensin II receptor blocker (ARB) might have benefits over non-ARB treatment.

31 Aug 2015

Research shows cold weather can increase risk of severe form of heart attack

Cold weather is associated with a higher risk of severe heart attack, according to research presented at ESC Congress today by Dr Shuangbo Liu, adult cardiology resident at the University of Manitoba in Winnipeg, Canada.

31 Aug 2015

Study: Knee or hip replacement surgery may increase heart attack risk

Contrary to recent reports, Boston-based researchers found that osteoarthritis patients who had total knee or hip joint replacement surgery, known as arthroplasty, were at increased risk of heart attack (myocardial infarction) in the early post-operative period.

31 Aug 2015

ESC guideline adherent antithrombotic management improves outcomes in AF patients

Patients with atrial fibrillation who receive antithrombotic management according to ESC guidelines have better outcomes than those who do not, according to one year follow up results from the ESC's EORP-AF Pilot General Registry presented today at ESC Congress 20151 and published online in Europace.

31 Aug 2015

Scientists discover the oldest case of leukemia in prehistoric female skeleton

Scientists of the Senckenberg Center for Human Evolution and Paleoenvironment and the University of Tübingen have discovered what may well be the oldest known case of Leukemia.

31 Aug 2015

MRA therapy does not improve outcome in heart attack patients without heart failure

Heart attack patients without heart failure derive no benefit from the addition of mineralocortoid receptor antagonists (MRA), to standard therapy, results of the ALBATROSS study show.

31 Aug 2015

Particulate matter, NO2 air pollution associated with increased risk of heart attacks

Particulate matter and NO2 air pollution are associated with increased risk of severe heart attacks despite being within European recommended levels, according to research presented at ESC Congress today by Dr Jean-Francois Argacha, a cardiologist at University Hospital Brussels (UZ Brussel-Vrije Universiteit Brussel), in Belgium.

31 Aug 2015

Study finds no significant impact of ATP on reducing late recurrence of AF

Late recurrence of atrial fibrillation (AF) is not reduced in patients whose pulmonary vein isolation (PVI) treatment incorporates the addition of adenosine triphosphate (ATP), according to results of the UNDER-ATP trial.

31 Aug 2015

Single dose of cocaine can impair ability to recognise negative emotions

A single dose of cocaine can interfere with the ability to recognise negative emotions, according to new research presented at the ECNP conference in Amsterdam.

31 Aug 2015

Medical Research News

Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Gene ZSCAN4 may help treat Down syndrome

Additional electrical isolation of left atrial appendage could improve freedom from AF

Study: Depressed patients three times more likely to experience frequent chest pain

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Leadless cardiac pacemakers could overcome complications of conventional transvenous pacemakers

TECOS analysis shows sitagliptin safe and effective in patients with type-2 diabetes, cardiovascular disease

Depression, blood pressure predict harmful vascular events in patients with heart disease, diabetes or stroke

Study shows food craving may be hard-wired into the brain of overweight patients

Stroke prevention strategies in elderly should focus on multiple risk factors

Depression and self-harm risk increased among goth teenagers

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

Research shows cold weather can increase risk of severe form of heart attack

Study: Knee or hip replacement surgery may increase heart attack risk

ESC guideline adherent antithrombotic management improves outcomes in AF patients

Scientists discover the oldest case of leukemia in prehistoric female skeleton

MRA therapy does not improve outcome in heart attack patients without heart failure

Particulate matter, NO2 air pollution associated with increased risk of heart attacks

Study finds no significant impact of ATP on reducing late recurrence of AF

Single dose of cocaine can impair ability to recognise negative emotions

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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