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CSF biomarkers predict dementia risk in PD patients

Early analysis of cerebrospinal fluid could help diagnose parkinsonian disorders and enhance the prediction of dementia in Parkinson’s disease patients, study results indicate.

19 Aug 2015

PHD1 inhibition may have therapeutic potential for colorectal cancer

Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy. Chemotherapy resistance remains a major clinical issue in the treatment of CRC. These findings indicate that PHD1 inhibition may have valuable therapeutic potential. The study was published in the leading medical journal EMBO Molecular Medicine, which features molecular biology-driven research.

19 Aug 2015

Immunization programmes face a growing challenge from vaccine hesitancy

People who delay or refuse vaccines for themselves or their children are presenting a growing challenge for countries seeking to close the immunization gap. Globally, one in 5 children still do not receive routine life-saving immunizations, and an estimated 1.5 million children still die each year of diseases that could be prevented by vaccines that already exist, according to the World Health Organization.

19 Aug 2015

Further understanding of genetic influence in ALS to be explored in new partnership

Biogen, the ALS Association and Columbia University Medical Center (CUMC) today announced a new collaboration to better understand the differences and commonalities in the ALS disease process and how genes influence the clinical features of the disease.

19 Aug 2015

Scientists reveal link between smaller hippocampal brain volume and marijuana use

How scientists study the effects of marijuana on the brain is changing. Until recently marijuana research largely excluded tobacco users from its participant pool, but scientists at the Center for BrainHealth at The University of Texas at Dallas have found reason to abandon this practice, uncovering significant differences in the brains of individuals who use both tobacco and marijuana and the brains of those who only use marijuana.

19 Aug 2015

Oncolytic virotherapy lends benefits to melanoma patients

Recent study published online by Melanoma Research journal indicates that melanoma patients would significantly benefit from prolonging the survival with oncolytic viroherapy treatment. The study revealed that the early stage melanoma patients treated with oncolytic medicine Rigvir were 4 to 6 times more likely to survive than those who following the current guidelines for the treatment of melanoma were only observed.

19 Aug 2015

UC Davis researchers set out to identify biomarkers for early diagnosis of lung cancer

Despite decades of warnings about smoking, lung cancer is still the second-most common cancer and the leading cause of death from cancer in the U.S. Patients are often diagnosed only when their disease is already at an advanced stage and hard to treat. Researchers at the West Coast Metabolomics Center at UC Davis are trying to change that, by identifying biomarkers that could be the basis of early tests for lung cancer.

19 Aug 2015

Discovery allows study of naturally occurring forms of HCV in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective treatments.

19 Aug 2015

Wearable devices or mobile apps can help track college students at risk of catching flu

New methods for analyzing personal health and lifestyle data captured through wearable devices or smartphone apps can help identify college students at risk of catching the flu, say researchers at Duke University and the University of North Carolina-Chapel Hill.

19 Aug 2015

NIH-funded Growing Resilience project to evaluate health impacts of food gardens

With a five-year, $2.5 million grant from the National Institutes of Health, University of Wyoming and Wind River Indian Reservation partners will evaluate the health impacts of food gardens with 100 Eastern Shoshone and Northern Arapaho families who would like to try home gardening.

19 Aug 2015

People near the middle of social hierarchies suffer higher rates of depression and anxiety

Individuals near the middle of the social hierarchy suffer higher rates of depression and anxiety than those at the top or bottom, according to researchers at Columbia University's Mailman School of Public Health.

19 Aug 2015

LINE-1 jumping gene unusually active in gastrointestinal cancer

Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers.

19 Aug 2015

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Dr. Badiavas’ research demonstrates how mesenchymal stem cell (MSC) exosomes, cell-derived vesicles that exist in biological fluids, function to repair non-healing wounds.

19 Aug 2015

E-cigarettes may trigger smoking in high school students, study reveals

Among high school students in Los Angeles, those who had ever used electronic cigarettes were more likely to report initiation of smokable ("combustible") tobacco (such as cigarettes, cigars, and hookah) use over the next year compared with nonusers, according to a study in the August 18 issue of JAMA.

19 Aug 2015

Researchers refine breast cancer risk model to give more accurate assessment

A national risk model that gauges a woman's chance of developing breast cancer has been refined to give a more accurate assessment. The revised figures, based on data from more than one million patients, reveal a 300 percent increase in a subset of women whose five-year risk is estimated at 3 percent or higher.

19 Aug 2015

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Doctor Scott Mueller and colleagues from the University of Melbourne's Department of Microbiology and Immunology at the Doherty Institute used state-of-the-art microscopy to painstakingly capture images of the interactions of three crucial types of immune cells rallying to destroy herpes simplex virus.

19 Aug 2015

Women's contraceptive choices often driven by relationships, sexual activity

Women's contraceptive choices are more often driven by current relationships and sexual activity than by long-term pregnancy intentions, according to Penn State College of Medicine researchers.

19 Aug 2015

Early exposure to inflammatory cytokines can paralyze CD4 T cells

In a discovery that is likely to rewrite immunology text books, researchers at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can "paralyze" CD4 T cells, immune components that help orchestrate the body's response to pathogens and other invaders.

19 Aug 2015

Rowan study reveals how exposure to Hurricane Sandy impacts mental health among older adults

Researchers from the Rowan University School of Osteopathic Medicine presented findings at the "2015 Hurricane Sandy Conference: Translating Research into Practice," showing that strong neighborhood relationships reduced the incidence of symptoms of post-traumatic stress disorder (PTSD) among older adults exposed to Hurricane Sandy, the superstorm that devastated the Northeast United States.

19 Aug 2015

Study raises possibility of using ultrasound techniques to detect symptoms of preterm labor

Researchers from North Carolina State University, Institut Langevin and Paris-Descartes University have conducted a proof-of-concept study that raises the possibility of using ultrasound techniques to detect cervical stiffness changes that indicate an increased risk of preterm labor in pregnant women.

19 Aug 2015

Medical Research News

CSF biomarkers predict dementia risk in PD patients

PHD1 inhibition may have therapeutic potential for colorectal cancer

Immunization programmes face a growing challenge from vaccine hesitancy

Further understanding of genetic influence in ALS to be explored in new partnership

Scientists reveal link between smaller hippocampal brain volume and marijuana use

Oncolytic virotherapy lends benefits to melanoma patients

UC Davis researchers set out to identify biomarkers for early diagnosis of lung cancer

Discovery allows study of naturally occurring forms of HCV in the lab

Wearable devices or mobile apps can help track college students at risk of catching flu

NIH-funded Growing Resilience project to evaluate health impacts of food gardens

People near the middle of social hierarchies suffer higher rates of depression and anxiety

LINE-1 jumping gene unusually active in gastrointestinal cancer

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

E-cigarettes may trigger smoking in high school students, study reveals

Researchers refine breast cancer risk model to give more accurate assessment

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Women's contraceptive choices often driven by relationships, sexual activity

Early exposure to inflammatory cytokines can paralyze CD4 T cells

Rowan study reveals how exposure to Hurricane Sandy impacts mental health among older adults

Study raises possibility of using ultrasound techniques to detect symptoms of preterm labor

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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