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Scientists show how malaria parasites invade the liver

Scientists at the Center for Infectious Disease Research recently uncovered a critical piece in the puzzle of how malaria parasites infect their host. The work, recently published in Science Magazine, reveals the details of how the malaria parasite invades its initial target organ, the liver. Without infection of the liver, the parasites cannot multiply or spread to the blood. Infection of the blood causes illness, spread of the disease, and, ultimately, death.

27 Nov 2015

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

The effect of a widespread genetic variant that increases the risk for childhood asthma can be neutralized. A new study shows that young infants are particularly responsive to the positive influence of exposure to farm dust.

27 Nov 2015

Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

A new study has shown that taking progesterone supplements during the first trimester of pregnancy does not improve the chances of maintaining pregnancy among women who have a history of unexplained recurrent miscarriage.

26 Nov 2015

New test can detect drug abuse faster

A new test for club drugs like ketamine can detect low levels of drugs in urine and plasma, making it faster, easier and cheaper to identify them. The authors of the study, published in Journal of Chromatography B, say it could give authorities the boost they need to keep up with trends drug (ab)use.

26 Nov 2015

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, an independent study of their genetic make-up suggests.

26 Nov 2015

Obese children with NAFLD not meeting recommended physical activity levels

In a new study published today in the journal Nutrients, research from the University of Surrey and the Children's Liver Disease Foundation has found that both obese children and those with Non-Alcoholic Fatty Liver Disease (NAFLD) are not meeting the UK recommendations for a variety of vitamins and minerals.

26 Nov 2015

Oxytocin hormone strengthens social ties

Nowadays, much emphasis is placed on sustainability. The degree to which people are willing to donate their own money for this depends on their level of oxytocin. Scientists at the University of Bonn Hospital have discovered that the willingness to donate increases with the quantity of this bonding hormone. However, oxytocin only has an effect with regard to social sustainability projects. The hormone does not increase the ability to participate in the case of purely environmentally oriented projects.

26 Nov 2015

Medical professionals compare different treatment options for Neuromyelitis optica

In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy.

26 Nov 2015

E. coli can move faster and farther in syrup-like fluids than in water, say Penn researchers

Swimming in a pool of syrup would be difficult for most people, but for bacteria like E. coli, it's easier than swimming in water. Scientists have known for decades that these cells move faster and farther in viscoelastic fluids, such as the saliva, mucus, and other bodily fluids they are likely to call home, but didn't understand why.

26 Nov 2015

IQWiG: Benefit of proteome analysis for detection of diabetic nephropathy remains unclear

The German Institute for Quality and Efficiency in Health Care examined the benefit of a diagnostic-therapeutic strategy using urinary proteome analysis for detection of diabetic nephropathy (DN) versus a conventional diagnostic strategy in patients with diabetes mellitus and arterial hypertension. After publication of the preliminary report in June 2015, interested persons and parties had the opportunity to comment on the preliminary results.

26 Nov 2015

Specific HRQOL components need to be targeted for achieving optimal care for older cancer patients

In a paper recently published in the European Journal of Cancer, EORTC researchers identified health related quality of life (HRQOL) components that should be considered as most relevant for achieving optimal care for older cancer patients.

26 Nov 2015

Researchers use magic-angle-spinning NMR to unveil structure of CAP-Gly protein

A latticework of tiny tubes called microtubules gives your cells their shape and also acts like a railroad track that essential proteins travel on. But if there is a glitch in the connection between train and track, diseases can occur.

26 Nov 2015

Lightpoint Medical obtains 2.4M Euro grant to carry out breast cancer clinical trial

Lightpoint Medical, an innovative medical device company specializing in imaging technologies, announced today that it has received a 2.4M Euro grant from the European Commission as part of the Horizon 2020 European Union Framework Programme for Research and Innovation, enabling the company to carry out a large-scale clinical trial in breast cancer.

26 Nov 2015

Opsin proteins contribute to heat-seeking movement of sperm

In their arduous journey to the egg, sperm "feel" the heat of the fallopian tube and "taste" the chemical signals of the ova. But a new Weizmann Institute of Science study published in Scientific Reports, in Nature, shows that sperm actually make quite a bit of use of sensors that have mainly been known to belong to the visual system.

26 Nov 2015

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

In the five decades since camptothecin was first isolated from the bark of a tree used in traditional Chinese medicine and identified as a powerful anticancer agent, several thousand chemicals with similar structures and functions have been investigated. And while two of these analog compounds, irinotecan and topotecan, have been approved in the U.S. as treatments for cancer, both are associated with significant shortcomings.

26 Nov 2015

Chikungunya may cause severe brain infection

The mosquito-borne virus chikungunya may lead to severe brain infection and even death in infants and people over 65, according to a new study that reviewed a chikungunya outbreak on Reunion Island off the coast of Madagascar in 2005-2006.

26 Nov 2015

Study sheds new light on the controversy surrounding common osteoarthritis treatment

Injections of hyaluronic acid (HA) are a common treatment of pain in osteoarthritis of the knee - a condition that affects 27 million Americans according to the Centers for Disease Control and Prevention. The injections replace natural HA that has depleted from one's joints, which can cause pain and stiffness due to the lack of lubrication between bones moving against each other.

26 Nov 2015

Study: Mother Nature may help lower cholesterol levels in pregnant women

When it comes to effective solutions for lowering cholesterol levels in pregnant women, Mother Nature may know best.

26 Nov 2015

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

What can a rare genetic childhood disease teach us about cancer? Dr. Ayelet Erez of the Weizmann Institute of Science's Department of Biological Regulation says: "A single-mutation disease can act as a 'lens.' If we find exactly what malfunctions in the sick child, we can zoom in and understand the role of the same gene among the many genetic changes that accompany cancer."

26 Nov 2015

Medical Research News

Scientists show how malaria parasites invade the liver

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

Researchers reveal new technique to grow human hepatocytes in the laboratory

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

New test can detect drug abuse faster

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Obese children with NAFLD not meeting recommended physical activity levels

Oxytocin hormone strengthens social ties

Medical professionals compare different treatment options for Neuromyelitis optica

E. coli can move faster and farther in syrup-like fluids than in water, say Penn researchers

IQWiG: Benefit of proteome analysis for detection of diabetic nephropathy remains unclear

Specific HRQOL components need to be targeted for achieving optimal care for older cancer patients

Researchers use magic-angle-spinning NMR to unveil structure of CAP-Gly protein

Lightpoint Medical obtains 2.4M Euro grant to carry out breast cancer clinical trial

Opsin proteins contribute to heat-seeking movement of sperm

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

Chikungunya may cause severe brain infection

Study sheds new light on the controversy surrounding common osteoarthritis treatment

Study: Mother Nature may help lower cholesterol levels in pregnant women

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

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