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Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

30 Jul 2015

Plants send out stress signals normally associated with animals

University of Adelaide research has shown for the first time that, despite not having a nervous system, plants use signals normally associated with animals when they encounter stress.

30 Jul 2015

Balancing cellular aging and cancer risk through biotechnology

In a way, trying to repair age-related heart damage and trying to fight cancer are opposite problems. Your heart cells' ability to regenerate themselves and proliferate into new, young cells degrades as you get older.

30 Jul 2015

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Superstorm Sandy continues to affect the lives of tens of thousands of New Jersey residents, in the form of unfinished repairs, disputed claims, and recurrent mold. These after-effects still linger for Sandy-impacted residents, and are associated with increased odds of residents experiencing mental health distress, post-traumatic stress disorder (PTSD), and depression.

30 Jul 2015

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Researchers at Barrow Neurological Institute have spent years of medical sleuthing across three continents to uncover a brain surgery that changed history.

30 Jul 2015

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

For consumers searching for just the right sunblock this summer, the options can be overwhelming. But scientists are now turning to the natural sunscreen of algae -- which is also found in fish slime -- to make a novel kind of shield against the sun's rays that could protect not only people, but also textiles and outdoor materials.

30 Jul 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Commonly prescribed drug also lowers blood pressure when combined with diuretic

With the growth of electronic medical records, research utilizing data from a large number of patients, known as big data studies, can provide important information which may be unattainable via clinical trials which tend to be costly, time-consuming and involve fewer patients.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

The ability to engage in mental time travel -- to delve back into past events or imagine future outcomes -- is a unique and central part of the human experience. And yet this very ability can have detrimental consequences for both physical and mental well-being when it becomes repetitive and uncontrolled.

30 Jul 2015

Cancer Research UK scientists identify five distinct types of prostate cancer

Cancer Research UK scientists have for the first time identified that there are five distinct types of prostate cancer and found a way to distinguish between them, according to a landmark study published today in EBioMedicine.

30 Jul 2015

Smaller doses of resveratrol more effective at preventing bowel cancer

Resveratrol, a chemical found in red grapes, is more effective in smaller doses at preventing bowel cancer in mice than high doses, according to new research published today (Wednesday) in the journal Science Translational Medicine.

30 Jul 2015

Race to meet EU biofuel targets could put human health at risk

The race to meet carbon-neutral biofuel targets could put human health and food crop production at risk unless it is carefully planned, according to new research.

30 Jul 2015

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

Patients undergoing surgery for lung cancer may wait too long to receive treatment, and too many patients skip vital diagnostic steps that are needed to help determine the best possible treatment, according to an article in the August 2015 issue of The Annals of Thoracic Surgery.

30 Jul 2015

Finding by UCSF researchers could increase availability of kidneys for transplant

Mild hypothermia in deceased organ donors significantly reduces delayed graft function in kidney transplant recipients when compared to normal body temperature, according to UC San Francisco researchers and collaborators, a finding that could lead to an increase in the availability of kidneys for transplant.

30 Jul 2015

Study reveals new way to help medical students learn about Alzheimer's disease

With the growing number of people with Alzheimer's disease, understanding their care is vital for doctors. Yet medical students often just learn the facts and may only see people with advanced disease who are at the hospital or nursing home. A study shows a new way to help medical students learn about the disease—at the art museum.

30 Jul 2015

Researchers identify link between individual characteristics and employment gap in people with disabilities

Researchers have explored the characteristics of people with disabilities who have achieved success in the workplace. The gap was found to be smaller among women, married people, individuals with higher educational achievement, Asians, and Hispanics, and people in their 20s and 60s.

30 Jul 2015

New study reports creation of genetic porcine model of cancer

With many types of cancers, early detection offers the best hope for survival. However, research into new early-detection screenings, as well as possible interventional radiology and surgical treatments, has been hindered by the lack of a large animal model that would accurately reflect the types of cancers seen in human cells.

30 Jul 2015

One sunburn increases risk of skin cancer by 50%

Everybody's got a story about that "one bad burn" - the time you fell asleep next to the pool and tattooed a white handprint on your lobster-red chest, or forgot to pack the sunscreen while hiking a Colorado 14er.

30 Jul 2015

Medical Research News

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

Plants send out stress signals normally associated with animals

Balancing cellular aging and cancer risk through biotechnology

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Commonly prescribed drug also lowers blood pressure when combined with diuretic

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

Cancer Research UK scientists identify five distinct types of prostate cancer

Smaller doses of resveratrol more effective at preventing bowel cancer

Race to meet EU biofuel targets could put human health at risk

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

Finding by UCSF researchers could increase availability of kidneys for transplant

Study reveals new way to help medical students learn about Alzheimer's disease

Researchers identify link between individual characteristics and employment gap in people with disabilities

New study reports creation of genetic porcine model of cancer

One sunburn increases risk of skin cancer by 50%

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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