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Stopping cocaine use may lower levels of ET-1 protein that plays key role in coronary artery disease

For people who use cocaine, stopping or reducing cocaine use is associated with decreased levels of endothelin-1 (ET-1)--a protein that plays a key role in the development of coronary artery disease, reports a study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

14 Jul 2015

Colorectal cancer patients diagnosed during screening colonoscopy survive longer

Patients whose colorectal cancer (CRC) is detected during a screening colonoscopy are likely to survive longer than those who wait until they have symptoms before having the test, according to a study in the July issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy.

14 Jul 2015

Newborn's first stool can signal future cognitive problems

A newborn's first stool can signal the child may struggle with persistent cognitive problems, according to Case Western Reserve University Project Newborn researchers.

14 Jul 2015

Novel gene therapy control system regulates expression of therapeutic transgenes

Korean researchers have described a novel control system to regulate the expression of a therapeutic transgene by targeting the passenger strand of a microRNA (miR-122) linked to the transgene.

14 Jul 2015

Postmenopausal women with kidney, bladder stones not at increased risk for osteoporosis

Postmenopausal women with kidney or bladder stones are not at increased risk for osteoporosis, but they do have about a 15 percent increased risk of another painful stone, physician-scientists report.

14 Jul 2015

Biosimilars show promise for children with IBD, but more research needed

Children with inflammatory bowel disease (IBD) who are doing well on specific biological medications should not be switched to recently approved "biosimilar" products, concludes an expert consensus statement of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition.

14 Jul 2015

Researchers identify genetic abnormalities that lead to skin SCC

Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused by an accumulation of genetic abnormalities in the progeny of single cells. The spectrum of genetic anomalies found in a variety of human cancers have been described.

14 Jul 2015

VUMC becomes Human Vaccines Project's first scientific hub

Vanderbilt University Medical Center, the Human Vaccines Project and the International AIDS Vaccine Initiative are pleased to announce that VUMC has become the Project's first scientific hub.

14 Jul 2015

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the protein keratin 17 - the presence of which is used in the lab to detect and stage various types of cancers - is not just a biomarker for the disease, but may play a critical role in tumor growth.

14 Jul 2015

University of Leeds scientists uncover genes implicated in common inherited diseases

Scientists from the University of Leeds have uncovered the most comprehensive list yet of genes implicated in a group of common inherited diseases.

14 Jul 2015

UM researchers discover new gene behind neurodegenerative conditions

Researchers at the University of Miami have discovered and characterized a previously unknown disease gene linked to the degeneration of optic and peripheral nerve fibers. The study titled "Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder" is published in the journal Nature Genetics.

14 Jul 2015

Chromosomes play active role in animal cell division

Canadian and British researchers have discovered that chromosomes play an active role in animal cell division. This occurs at a precise stage - cytokinesis - when the cell splits into two new daughter cells.

14 Jul 2015

Gene function in the human brain could help reveal basis of autism

UNSW Australia scientists have discovered a link between autism and genetic changes in some segments of DNA that are responsible for switching on genes in the brain.

14 Jul 2015

Researchers identify protein responsible for preserving antibody-producing cells that lead to long-term immunity

Melbourne researchers have identified a protein responsible for preserving the antibody-producing cells that lead to long-term immunity after infection or vaccination.

14 Jul 2015

Study shows that Anisina has potential to improve effectiveness of chemotherapy in children with cancer

US-Australian drug discovery company, Novogen Limited, today announced details of an in vivo proof of concept study that demonstrates their lead anti-tropomyosin drug candidate, Anisina, has the potential to improve the effectiveness of chemotherapy in children and reduce life-long side-effects.

14 Jul 2015

University of Twente scientists take significant step in breast cancer research

Scientists at the research Institute MIRA at the University of Twente have been working for some time on a new technique to detect breast cancer. The technique based on the physical principle of photoacoustics, has been christened PAMmography. It uses short bursts of light that cause ultrasonic waves to be generated in places with high density of blood vessels, such as in the vicinity of malignant tumours.

13 Jul 2015

New incoming nerve cell connections could be contributing to age-related hearing loss, say Johns Hopkins scientists

Conventional wisdom has long blamed age-related hearing loss almost entirely on the death of sensory hair cells in the inner ear, but research from neuroscientists at Johns Hopkins has provided new information about the workings of nerve cells that suggests otherwise.

13 Jul 2015

Researchers discover role of RORC mutations in patients with candidiasis and mycobacteriosis

The discovery of bi-allelic mutations in RORC in patients with candidiasis and mycobacteriosis revealed the pivotal role of RORC in mucocutaneous immunity to Candida and in systemic immunity to Mycobacterium in humans.

13 Jul 2015

Researchers examine limits of human hearing

Are wind farms harmful to humans? Some believe so, others refute this; this controversial topic makes emotions run high. To give the debate more objectivity, an international team of experts dealt with the fundamentals of hearing in the lower limit range of the audible frequency range (i.e. infrasound), but also in the upper limit range (i.e. ultrasound).

13 Jul 2015

Study offers new way to suppress growth factors related to cancer cell proliferation

Cancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human cleavage enzymes. A pharmaceutical blocking of these enzymes could hinder cancer from growing but would also inhibit other life-essential processes.

13 Jul 2015

Medical Research News

Stopping cocaine use may lower levels of ET-1 protein that plays key role in coronary artery disease

Colorectal cancer patients diagnosed during screening colonoscopy survive longer

Newborn's first stool can signal future cognitive problems

Novel gene therapy control system regulates expression of therapeutic transgenes

Postmenopausal women with kidney, bladder stones not at increased risk for osteoporosis

Biosimilars show promise for children with IBD, but more research needed

Researchers identify genetic abnormalities that lead to skin SCC

VUMC becomes Human Vaccines Project's first scientific hub

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

University of Leeds scientists uncover genes implicated in common inherited diseases

UM researchers discover new gene behind neurodegenerative conditions

Chromosomes play active role in animal cell division

Gene function in the human brain could help reveal basis of autism

Researchers identify protein responsible for preserving antibody-producing cells that lead to long-term immunity

Study shows that Anisina has potential to improve effectiveness of chemotherapy in children with cancer

University of Twente scientists take significant step in breast cancer research

New incoming nerve cell connections could be contributing to age-related hearing loss, say Johns Hopkins scientists

Researchers discover role of RORC mutations in patients with candidiasis and mycobacteriosis

Researchers examine limits of human hearing

Study offers new way to suppress growth factors related to cancer cell proliferation

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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