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Call for improvements in CVD risk models

There are too many poorly validated models for predicting cardiovascular disease risk in the general population, researchers report in The BMJ.

19 May 2016

Strategy choice impacts long-term mortality in bifurcation stenting

Using a provisional rather than a planned two-stent strategy for coronary bifurcation stenting may halve long-term mortality, pooled study data show.

19 May 2016

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants

Very preterm infants do not gain protection against neurodevelopmental delay with early prophylactic high-dose recombinant human erythropoietin, researchers report.

19 May 2016

Ramizol drug shows promise in treatment of Clostridium difficile infections

A scientific paper released today in the Journal of Antibiotics presents the pre-clinical development of Ramizol, a first generation drug belonging to a new class of styrylbenzene antibiotics with a novel mechanism of action.

19 May 2016

More neonatal infection research could drive forward measures to reduce infant deaths

No one knows how many newborns are dying each year due to antibiotic resistant infections, because of a lack of funding to research the issue fully, Professor Mike Sharland from St George's, University London said.

19 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Flavopiridol drug could be effective strategy to impair brain cancer growth

Glioblastoma, the most common form of brain cancer is a deadly disease for which at present there is no cure. Now, researchers have published research results that show how repurposing the old drug flavopiridol could be an effective strategy to cut short sugar availability and impair cancer growth.

19 May 2016

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

For the first time, researchers were able to demonstrate that children diagnosed with sickle cell disease showed improvement in lung function after treatment with hydroxyurea, a treatment that is underused despite its demonstrated benefits.

19 May 2016

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Insilico Medicine collaborates with National Laboratory Astana to study age-related pathologies

Insilico Medicine announced an agreement with National Laboratory Astana, Nazarbayev University, one of the most rapidly growing universities in the world to collaboratively study aging and age-associated pathologies.

19 May 2016

Understanding antibody transport mechanisms in the brain

Diseases of the central nervous system (CNS), such as stroke, brain cancer, and Alzheimer's disease, are a serious threat affecting over 50 million Americans with an associated cost of over $750 billion per year, which is expected to grow significantly over the coming decades.

19 May 2016

Fluorescent proteins help trace viral infections

Researchers at Umea University have developed a new method to directly follow viral infections in living organisms. This method can make infected cells produce fluorescent proteins, which means that they light up and become easier to identify.

19 May 2016

ICS users may be at greater risk for nontuberculous mycobacteria pulmonary disease

Patients with obstructive lung disease who take inhaled corticosteroids (ICS) may be at greater risk for nontuberculous mycobacteria pulmonary disease (NTM PD), according to new research presented at the ATS 2016 International Conference.

19 May 2016

Mouse model of depression can help better understand how ketamine functions

New research demonstrates the effectiveness of ketamine to treat depression in a mouse model of the disease and brings together two hypotheses for the cause of depression.

19 May 2016

High blood pressure could increase vascular dementia risk

High blood pressure could significantly raise the risk of developing the second most common form of dementia, according to a new study from The George Institute for Global Health.

19 May 2016

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Acute HIV infection (AHI) contributes significantly to HIV transmission and may be important for intervention strategies seeking to reduce incidence and achieve a functional cure.

19 May 2016

Taking pregabalin drug during pregnancy could lead to major birth defects

A drug commonly used to treat pain, epilepsy, anxiety and other brain health disorders may be associated with an increased risk of major birth defects, according to a study published in the May 18, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 May 2016

Medical Research News

Call for improvements in CVD risk models

Strategy choice impacts long-term mortality in bifurcation stenting

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants

Ramizol drug shows promise in treatment of Clostridium difficile infections

More neonatal infection research could drive forward measures to reduce infant deaths

Natural product darwinolide may help combat fatal MRSA infection

Flavopiridol drug could be effective strategy to impair brain cancer growth

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

Insilico Medicine collaborates with National Laboratory Astana to study age-related pathologies

Understanding antibody transport mechanisms in the brain

Fluorescent proteins help trace viral infections

ICS users may be at greater risk for nontuberculous mycobacteria pulmonary disease

Mouse model of depression can help better understand how ketamine functions

High blood pressure could increase vascular dementia risk

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Taking pregabalin drug during pregnancy could lead to major birth defects

Introducing allergenic foods early in life may decrease sensitization risk

Research sheds light on potential impact of HCV treatment in preventing virus transmission

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

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