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DME treatment evolves in favour of intravitreal anti-VEGF injections

Treatment strategies for diabetic macular oedema have evolved over the past decade, with focal laser therapy being largely replaced by intravitreal injections, an observational case series of more than 1500 patients shows.

8 Jul 2015

Retinal function, structure changes in proliferative diabetic retinopathy revealed

Patients with proliferative diabetic retinopathy exhibit marked visual dysfunction and structural changes in both the inner and outer retinal layers, research findings indicate.

8 Jul 2015

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Progression and severity of macular atrophy are the main anatomical determinants of long-term visual outcomes in exudative age-related macular degeneration patients treated with ranibizumab, suggest SEVEN-UP study results.

8 Jul 2015

Darapladib shows promise in diabetic macular oedema

Placebo-controlled trial findings show that lipoprotein-associated phospholipase A2 inhibition modestly benefits the vision of patients with centre-involved diabetic macular oedema and warrants further investigation.

8 Jul 2015

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, in the direct vicinity of the tumor they lose their effect.

8 Jul 2015

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

Trovagene, Inc., a developer of cell-free molecular diagnostics, today announced the launch of a study that aims to determine utility of the Company's Precision Cancer Monitoring (PCM) technology for predicting response to treatment in advanced melanoma patients receiving one or a combination of the novel immunotherapy agents Yervoy (ipilumumab), a CTLA-4 inhibitor, and Opdivo (nivolumab), a PD-1 inhibitor.

8 Jul 2015

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

Certain genetic diseases arise from a deficit of specific genes. An enzyme that amplifies gene transcription could be a viable therapy in these cases, as long as genes are not stimulated to work on the wrong part of the body. SISSA scientists have created synthetic "intelligent" enzymes which are able to differentiate between active and inactive genes and selectively stimulate the former ones.

8 Jul 2015

Evidence-based initiative aims to prevent avoidable hospital readmissions

A statewide effort led by key stakeholders in South Carolina successfully organized and implemented an evidence-based initiative aimed at improving the quality of healthcare transitions after hospital discharge to prevent avoidable readmissions.

8 Jul 2015

Modified, healthier meal plan for youth with type 1 diabetes more expensive

Patients with type 1 diabetes mellitus (T1DM) often need to modify their eating habits, but many youths with T1DM do not consume a healthful diet. To learn more about the challenges their parents may face in providing them with a more healthful diet, researchers set out to discover the availability of healthier food options and the price difference of the food items at stores frequented by families in northeastern Kansas and western Missouri.

8 Jul 2015

City of Hope offers islet cell transplant program to cure type 1 diabetes

For patients with severe type 1 diabetes, a strict diet and insulin shots are sometimes not enough to sufficiently control their disease. What they need are insulin-producing cells of their own - currently only available through a still-experimental procedure known as islet cell transplantation.

8 Jul 2015

Adolescents more likely to try e-cigarettes when exposed to TV ads

Adolescents who are exposed to e-cigarette TV advertising are more likely to try e-cigarettes in the future, according to a groundbreaking experiment from researchers at RTI International. Although advertising and adolescent use of e-cigarettes have simultaneously increased in recent years, this is the first study to demonstrate a direct link between adolescents' exposure to advertising and their likelihood of future use.

8 Jul 2015

New research shows that pupil response can predict child's risk of depression

How much a child's pupil dilates in response to seeing an emotional image can predict his or her risk of depression over the next two years, according to new research from Binghamton University.

8 Jul 2015

Sepsis readmissions have significant impact on health care expenditures in California

The Affordable Care Act created several national initiatives aimed at reducing hospital readmission rates for heart attacks, congestive heart failure and other common high-risk conditions. But there is still no national program intended to address sepsis, a potentially life-threatening illness caused by infection.

8 Jul 2015

People who survive stroke may experience accelerated and persistent decline in cognitive function

In a study that included nearly 24,000 participants, those who experienced a stroke had an acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years, according to an article in the July 7 issue of JAMA.

8 Jul 2015

Study examines recent trends in community-based practices to improve management of localized prostate cancer

After years of overtreatment for patients with low-risk prostate cancer, rates of active surveillance/ watchful waiting increased sharply in 2010 through 2013, and high-risk disease was more often treated appropriately with potentially curative local treatment rather than androgen deprivation alone, according to a study in the July 7 issue of JAMA.

8 Jul 2015

Findings shed light on how symmetrical, round cells become polarized and directional

When Greek mythology and cell biology meet, you get the protein Callipygian, recently discovered and named by researchers at The Johns Hopkins University for its role in determining which area of a cell becomes the back as it begins to move.

8 Jul 2015

Researchers identify link between hormonal factors and endometrial cancer risk among women with Lynch syndrome

For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study in the July 7 issue of JAMA. Lynch syndrome is a genetic condition that increases the risk for various cancers.

8 Jul 2015

Finding could help improve health and function of the kidney in elderly people

As advances in medicine allow individuals to live longer, people are facing unique age-related health challenges. As they age, organs such as the kidneys become more susceptible to injury, and their ability to self-repair is decreased. Researchers from the University of Missouri have found a cellular signal that causes kidney cells to die, making the kidneys prone to injury.

8 Jul 2015

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer's disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.

8 Jul 2015

News study shows pregnancy complications tied to future cardiovascular disease risk

According to a new study, women can accurately recall key pregnancy-related information at least 4 years later that could have important implications for their future risk of developing cardiovascular disease (CVD).

8 Jul 2015

Medical Research News

DME treatment evolves in favour of intravitreal anti-VEGF injections

Retinal function, structure changes in proliferative diabetic retinopathy revealed

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Darapladib shows promise in diabetic macular oedema

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

Evidence-based initiative aims to prevent avoidable hospital readmissions

Modified, healthier meal plan for youth with type 1 diabetes more expensive

City of Hope offers islet cell transplant program to cure type 1 diabetes

Adolescents more likely to try e-cigarettes when exposed to TV ads

New research shows that pupil response can predict child's risk of depression

Sepsis readmissions have significant impact on health care expenditures in California

People who survive stroke may experience accelerated and persistent decline in cognitive function

Study examines recent trends in community-based practices to improve management of localized prostate cancer

Findings shed light on how symmetrical, round cells become polarized and directional

Researchers identify link between hormonal factors and endometrial cancer risk among women with Lynch syndrome

Finding could help improve health and function of the kidney in elderly people

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

News study shows pregnancy complications tied to future cardiovascular disease risk

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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