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Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer's disease (AD) and Down syndrome (DS).

12 Apr 2016

Study shows 37% of outpatient healthcare staff fail to follow hand hygiene recommendations

Despite having policies in place to prevent infections, staff at outpatient care facilities fail to follow recommendations for hand hygiene 37 percent of the time, and for safe injection practices 33 percent of the time, according to a study published in the April issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology.

12 Apr 2016

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

In a new study, a research team at Basel University Hospital in Switzerland investigates the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.

12 Apr 2016

Mild traumatic brain injury can affect quality of parent-child relationships

A study published in the Journal of Neuropsychology, reveals the adverse effects of mild traumatic brain injury (mTBI) on the quality parent-child relationships. The young brain is particularly vulnerable to injury and one of the first visible signs of social difficulties in young children is a decline in their relationship with their parents. Parents should watch for emotional and behavioural changes in their children.

12 Apr 2016

E-cigarette smoking has more deleterious short-term effects on pulmonary function in asthmatic smokers

E-cigarette smoking is increasingly promoted as a safer alternative to cigarette smoking, but a growing body of evidence points to its potential dangers. Adding to the evidence, researchers will report at CHEST World Congress this month on a study of e-cigarettes and the immediate effects on pulmonary function in healthy and mild asthmatic young smokers.

12 Apr 2016

Low-level exposures to air pollution may affect normal lung function in children

Dramatic improvements in air quality in U.S. cities since the 1990s may not be enough to ensure normal lung function in children, according to new research published in the April 15 American Journal of Respiratory and Critical Care, a journal of the American Thoracic Society.

12 Apr 2016

$Bronchial thermoplasty improves quality of life for severe refractory asthmatics$

Bronchial thermoplasty improves quality of life for severe refractory asthmatics

Among people with asthma, lower socioeconomic status, education level, and ethnic minority status clearly have undesirable effects on their care and outcomes. Patients with severe disease who attend county (public) hospitals in the United States tend to have less access to resources, which, in addition to environmental and compliance issues, may contribute to poorer disease control.

12 Apr 2016

Increased BMP7 levels predict PAH mortality

Elevated levels of circulating bone morphogenetic protein 7 are associated with an increased mortality risk in patients with pulmonary arterial hypertension, find Chinese researchers.

12 Apr 2016

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

12 Apr 2016

Researchers develop new technology to tailor grafted tissues

Researchers from the Technion-Israel Institute of Technology and colleagues in the U.S. have developed technology to tailor grafted tissues that can respond to certain natural forces affecting blood vessels.

12 Apr 2016

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Brazilian researchers from the D'Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have demonstrated the harmful effects of ZIKA virus (ZIKV) in human neural stem cells, neurospheres and brain organoids.

12 Apr 2016

Certain red blood cell manufacturing methods may be less damaging to cells than others

Scientists from Blood Systems Research Institute in San Francisco, California, and Canadian Blood Services' Centre for Innovation lab in Edmonton, Alberta, report for the first time that specific red blood cell manufacturing methods may be less damaging to cells than others.

12 Apr 2016

New plant-derived oral drug can prevent progression of multiple sclerosis

An international research team has demonstrated that a new plant-derived drug can block the progression of multiple sclerosis (MS).

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Increased expression of VEGF-A promotes three common aging-related eye conditions

A Massachusetts General Hospital investigator has found that increased expression of the angiogenic factor VEGF-A promotes three common aging-related eye conditions - both versions of age-related macular degeneration (AMD) and also cataracts - in an animal model.

12 Apr 2016

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire within--allowing electrical and chemical impulses to travel faster.

12 Apr 2016

Marriage may help prolong survival in cancer patients

New research has uncovered a link between being married and living longer among cancer patients, with the beneficial effect of marriage differing by race/ethnicity and place of birth. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings have important public health implications, given the rising numbers of unmarried individuals in the United States in addition to the growing aging population.

12 Apr 2016

Medical Research News

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Study shows 37% of outpatient healthcare staff fail to follow hand hygiene recommendations

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

Mild traumatic brain injury can affect quality of parent-child relationships

E-cigarette smoking has more deleterious short-term effects on pulmonary function in asthmatic smokers

Low-level exposures to air pollution may affect normal lung function in children

Bronchial thermoplasty improves quality of life for severe refractory asthmatics

Increased BMP7 levels predict PAH mortality

BMPR2 mutations affect outcomes of PAH patients

Researchers develop new technology to tailor grafted tissues

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Certain red blood cell manufacturing methods may be less damaging to cells than others

New plant-derived oral drug can prevent progression of multiple sclerosis

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Increased expression of VEGF-A promotes three common aging-related eye conditions

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

Marriage may help prolong survival in cancer patients

Zonisamide relieves myoclonus dystonia motor symptoms

HIIT workout with integral electro-stimulation better than conventional aerobic exercise

Complete genetic map of scleroderma opens door for diagnosis and targeted treatment

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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