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Researchers find link between acute hospitalizations and disability among older adults at the end of life

Yale researchers found a close association between acute hospitalizations and the development and progression of disability among older adults at the end of life. Their findings may have profound implications for medical decision-making for older people and those who care for them.

21 May 2015

Kidney function plays critical role in sepsis patients

Researchers at Duke Medicine have determined that kidney function plays a critical role in the fate of patients being treated for sepsis, a potentially life-threatening complication of an infection.

21 May 2015

Anti-VEGF therapy benefits in wet AMD not sustained

Real-world experience of anti-vascular endothelial growth factor therapy for patients with wet age-related macular degeneration suggests that initial improvements in visual acuity are not maintained over time.

20 May 2015

Submacular air injection aids tPA haemorrhage displacement

Submacular air injection with a microneedle is effective at facilitating the displacement of massive submacular haemorrhages dissolved with tissue plasminogen activator in patients with age-related macular degeneration, an interventional case series shows.

20 May 2015

Heavy metallic elements influence AMD progression

Researchers report associations between age-related macular degeneration and five heavy metallic elements, in findings that highlight the detrimental effects of pollution but the possible benefits of essential elements supplementation.

20 May 2015

AMD severity and progression tracks across eyes

Age-related macular degeneration in one eye tracks the severity of it in the fellow eye at all stages of the disease, findings from the Beaver Dam Eye study show.

20 May 2015

Research may offer new targets for diagnosing, treating advanced prostate cancer

Researchers with the Indiana University School of Medicine have identified a molecule that promotes metastasis of advanced prostate cancer to the bone, an incurable condition that significantly decreases quality of life.

20 May 2015

In-house training solutions from PTI: save time and cost in upskilling staff

With course topics that include, but aren’t limited to, business strategy, clinical trials, manufacturing, R&D and regulatory affairs, PTI covers all aspects of the drug and device development lifecycle...

From Pharmaceutical Training International 20 May 2015

Merus and Selexis receive a € 2.1 million grant for single cell line manufacturing of a bispecific antibody combination to treat colorectal cancer

Merus and Selexis will combine their unique and proprietary Oligoclonics® and SUREtechnology™ platforms respectively to develop a product combining two bispecific full length IgG antibodies that simultaneously targets and potently inhibits three receptor tyrosine kinases...

20 May 2015

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Two studies from Johns Hopkins Kimmel Cancer Center researchers add to preliminary evidence that high-dose radiation treatment, called stereotactic body radiotherapy, appears to be safe and as effective as standard radiation treatment for certain patients with pancreatic cancer whose tumors are advanced but have not spread.

20 May 2015

Scientists find key to light-induced color change in fish skin

The neon tetra fish from the Amazonas River, along with some reptiles, amphibians, and other fish, takes advantage of structural colors in its skin to change its appearance in response to a triggering signal. In the light-adapted state, its lateral stripe shimmers blue-green, in the dark it is indigo. Scientists from Israel have now found an unambiguous answer to how this intriguing mechanism works. They present their results, which favor the so-called "Venetian blind" model, in the journal Angewandte Chemie.

20 May 2015

Research shows how immune system controls biological clock in times of inflammation, infection

Researchers at Trinity College Dublin and the University of Pennsylvania have uncovered an important link between our body clock and the immune system that will have relevance to the treatment of inflammatory and infectious diseases.

20 May 2015

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Clinical experience of biosimilar infliximab in 78 inflammatory bowel disease (IBD) patients presented at Digestive Diseases Week (DDW) 2015 in Washington D.C. showed that the treatment is comparable to the reference medicinal product (RMP) in terms of efficacy and safety.

20 May 2015

Large urban health systems do worse on government patient satisfaction scores

The largest urban health systems, which serve as safety nets for large patient populations with lower socioeconomic status and greater likelihood to speak English as a second language, do worse on government patient satisfaction scores than smaller, non-urban hospitals likely to serve white customers with higher education levels, according to a new study by Mount Sinai researchers published this month in the Journal of Hospital Medicine.

20 May 2015

New study suggests ways to accelerate recovery from dangerous diarrheal disease

A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.

20 May 2015

Teens with slower cognitive processing speed experience depression, anxiety symptoms as adults

Teens with slower performance on a test of "cognitive processing speed" are more likely to have depression and anxiety symptoms as adults, reports a paper in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society.

20 May 2015

Specific bacterial community in female genital tract induces inflammation, increases HIV risk

A team led by researchers from Massachusetts General Hospital and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract among healthy South Africa women not only is significantly different from that of women in developed countries but also leads to elevated levels of inflammatory proteins.

20 May 2015

HIV infections continue to rise among YMSM despite prevention efforts

HIV infections continue to rise in a new generation of young, gay, bisexual and other men who have sex with men (YMSM) despite three decades of HIV prevention as well as recent availability of biomedical technologies to prevent infection.

20 May 2015

Diabetes screening will overwhelm India’s health system, study predicts

The new study, which used mathematical models to simulate the outcome of screening the whole population, estimates that between 158 million and 306 million people would be referred for confirmatory testing, but only 26-37 million of those would meet the diagnostic criteria for diabetes...

20 May 2015

Nerve cells guide each other during embryonic development

When nerve cells form in an embryo they do not start off in the right place but have to be guided to their final position by navigating a kind of molecular and cellular "map" in order to function properly. In a recent research study published in Nature Communications neurobiologist Sara Wilson, Umeå University, found that during embryonic development different parts of the nerve cell are important for guiding other nerve cells into their physical positions.

20 May 2015

Medical Research News

Researchers find link between acute hospitalizations and disability among older adults at the end of life

Kidney function plays critical role in sepsis patients

Anti-VEGF therapy benefits in wet AMD not sustained

Submacular air injection aids tPA haemorrhage displacement

Heavy metallic elements influence AMD progression

AMD severity and progression tracks across eyes

Research may offer new targets for diagnosing, treating advanced prostate cancer

In-house training solutions from PTI: save time and cost in upskilling staff

Merus and Selexis receive a € 2.1 million grant for single cell line manufacturing of a bispecific antibody combination to treat colorectal cancer

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Scientists find key to light-induced color change in fish skin

Research shows how immune system controls biological clock in times of inflammation, infection

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Large urban health systems do worse on government patient satisfaction scores

New study suggests ways to accelerate recovery from dangerous diarrheal disease

Teens with slower cognitive processing speed experience depression, anxiety symptoms as adults

Specific bacterial community in female genital tract induces inflammation, increases HIV risk

HIV infections continue to rise among YMSM despite prevention efforts

Diabetes screening will overwhelm India’s health system, study predicts

Nerve cells guide each other during embryonic development

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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