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Constraint-induced movement therapy trialled in patients’ homes

A randomised trial from Germany has attempted to turn constraint-induced movement therapy into a cost-effective home-based treatment for stroke survivors.

7 Aug 2015

TSRI study explores bacterial enzyme that may help people to quit smoking

A new study from scientists at The Scripps Research Institute explores a bacterial enzyme that might be used as a drug candidate to help people quit smoking.

7 Aug 2015

CHOP-led national clinical research network approved for $8.6 million funding award by PCORI

PEDSnet, a national clinical research network co-led by a pediatric researcher at The Children's Hospital of Philadelphia, was approved for an $8.6 million, three-year funding award by the Patient-Centered Outcomes Research Institute.

7 Aug 2015

Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

Autopsies of nearly every patient with the lethal neurodegenerative disorder amyotrophic lateral sclerosis (ALS), and many with frontotemporal dementia (FTD), show pathologists telltale clumps of a protein called TDP-43. Now, working with mouse and human cells, Johns Hopkins researchers report they have discovered the normal role of TDP-43 in cells and why its abnormal accumulation may cause disease.

7 Aug 2015

Patient-funded trials may threaten to de-stabilize system that guarantees high quality results

In the era of launching Kickstarter campaigns to pay for just about anything, Carnegie Mellon University ethicists warn that the trend of patients funding their own clinical trials may do more harm than good.

7 Aug 2015

Study: Dietary carbohydrate essential for evolution of modern big-brained humans

Understanding how and why we evolved such large brains is one of the most puzzling issues in the study of human evolution. It is widely accepted that brain size increase is partly linked to changes in diet over the last 3 million years, and increases in meat consumption and the development of cooking have received particular attention from the scientific community.

7 Aug 2015

Scientists publish new important clues about marrow fat

While most of us worry about the fat cells building up on the fleshy parts of our bodies, scientists have started to pay serious attention to another kind of fat cell deep inside our bones, in what's called the marrow.

7 Aug 2015

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Chromosomes are responsible for carrying our genes and essentially protecting the information that helps ensure normal, healthy growth, with vital instructions being passed on from cell to cell by a process known as mitosis. While this copying mechanism has been well understood for decades, scientists have been unable to describe exactly how genetic information is protected and properly segregated as mitosis is happening.

7 Aug 2015

Eating too many refined carbohydrates may increase depression risk

A study published this week indicates that a diet high in refined carbohydrates may increase the risk of developing depression.

7 Aug 2015

New technology that tracks patients' eye movements may accurately measure brain injury

New technology that tracks the eye movements of patients may be a more accurate measure of brain injury than any other diagnostic measurements currently in use, according to a study recently published in the journal Concussion.

7 Aug 2015

Researcher reveals link between inflammatory response of neutrophils and spread of oral cancer

An abnormal immune response or "feedback loop" could very well be the underlying cause of metastases in oral cancers, according to Dr. Marco Magalhaes, Assistant Professor at the University of Toronto's Faculty of Dentistry and lead researcher in a study published in the journal Cancer Immunology Research.

7 Aug 2015

Experts explain how nutrition can influence inflammatory processes and help lower chronic diseases risk

An unresolved inflammatory response is likely to be involved from the early stages of disease development. Controlling inflammation is crucial to human health and a key future preventative and therapeutic target. In a recent ILSI Europe's article published in the British Journal of Nutrition, a coalition of experts explain how nutrition influences inflammatory processes and help reduce chronic diseases risk.

7 Aug 2015

First self-assessment test developed to help clinicians diagnose autism in adults

Psychologists from Cardiff University have developed the first self-assessment test designed to help clinicians diagnose autism in adults.

7 Aug 2015

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body's natural infection-control defenses.

7 Aug 2015

UNC researchers show how a genetic mutation disables molecular switch and causes autism

Last December, researchers identified more than 1,000 gene mutations in individuals with autism, but how these mutations increased risk for autism was unclear. Now, UNC School of Medicine researchers are the first to show how one of these mutations disables a molecular switch in one of these genes and causes autism.

7 Aug 2015

Shorter course of whole breast radiation therapy better for women with early stage breast cancer

Women who receive a shorter course of whole breast radiation therapy for early stage disease experience less toxicity and improved quality of life compared to those who undergo a longer course of treatment, researchers report from The University of Texas MD Anderson Cancer Center.

7 Aug 2015

BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

Researchers at Beth Israel Deaconess Medical Center have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases.

7 Aug 2015

Imaging studies required to diagnose traumatic injuries in pregnant women can be safe when used properly

According to a new study in the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), imaging studies necessary to diagnose traumatic injuries sustained by pregnant women are safe when used properly.

7 Aug 2015

Many older adults tend to overestimate their mobility

Many seniors who visit emergency departments require more assistance with physical tasks than they think they do, which may lead to hospital readmission later on. The results of the study were published online Friday in Annals of Emergency Medicine ("Self-Reported vs. Performance-Based Assessments of a Simple Mobility Task Among Older Adults in the Emergency Department").

7 Aug 2015

Urban emergency department sees high rates of HCV infection among intravenous drug users, Baby Boomers

An urban emergency department that set up a hepatitis C testing protocol saw high rates of infection among intravenous drug users and Baby Boomers, with three-quarters of those testing positive unaware they were infected.

7 Aug 2015

Medical Research News

Constraint-induced movement therapy trialled in patients’ homes

TSRI study explores bacterial enzyme that may help people to quit smoking

CHOP-led national clinical research network approved for $8.6 million funding award by PCORI

Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

Patient-funded trials may threaten to de-stabilize system that guarantees high quality results

Study: Dietary carbohydrate essential for evolution of modern big-brained humans

Scientists publish new important clues about marrow fat

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Eating too many refined carbohydrates may increase depression risk

New technology that tracks patients' eye movements may accurately measure brain injury

Researcher reveals link between inflammatory response of neutrophils and spread of oral cancer

Experts explain how nutrition can influence inflammatory processes and help lower chronic diseases risk

First self-assessment test developed to help clinicians diagnose autism in adults

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

UNC researchers show how a genetic mutation disables molecular switch and causes autism

Shorter course of whole breast radiation therapy better for women with early stage breast cancer

BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

Imaging studies required to diagnose traumatic injuries in pregnant women can be safe when used properly

Many older adults tend to overestimate their mobility

Urban emergency department sees high rates of HCV infection among intravenous drug users, Baby Boomers

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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