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Molecular on-off switch controls how mouse brain responds to vision loss

KU Leuven biologists have discovered a molecular on-off switch that controls how a mouse brain responds to vision loss.

13 Aug 2015

Higher-fit kids have significantly thinner gray matter, better mathematics achievement than their low-fit peers

A new study reveals that 9- and 10-year-old children who are aerobically fit tend to have significantly thinner gray matter than their "low-fit" peers. Thinning of the outermost layer of brain cells in the cerebrum is associated with better mathematics performance, researchers report in the journal PLOS ONE.

13 Aug 2015

First clinical trial to test use of retinal progenitor cells for treating retinitis pigmentosa begins

Participants are being enrolled in the first clinical trial that tests the use of retinal progenitor cells to treat retinitis pigmentosa, reported project director Dr. Henry Klassen of UCI's Gavin Herbert Eye Institute and Sue & Bill Gross Stem Cell Research Center. The product of stem cell research at UCI, these retinal progenitors are similar to stem cells in terms of potential regenerative properties, but they're specific to the retina.

13 Aug 2015

New MRI contrast agent detects tiny breast cancer tumors, micrometastases

Researchers at Case Western Reserve University have developed a magnetic resonance imaging (MRI) contrast agent that detects much smaller aggressive breast cancer tumors and micrometastases than current agents can identify.

13 Aug 2015

Tumor cells associated with pancreatic cancer work with each other to increase tumor spread

Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread, according to new research from the Perelman School of Medicine at the University of Pennsylvania published in Cancer Discovery online in advance of the print issue.

13 Aug 2015

Study identifies two key traits involved in development of obsessive-compulsive disorder

Confusing reality with imagination and losing contact with reality are two key characteristics that could play a role in the development of obsessive-compulsive disorder (OCD). This is what we learn from a study conducted by researchers at the CIUSSS de l'Est-de-l'Île-de-Montréal (Institut universitaire en santé mentale de Montréal) and the University of Montreal, the results of which were published in the Journal of Clinical Psychology.

13 Aug 2015

Researchers identify novel brain network that plays wide role in memory and learning processes

One of the more heartbreaking realities of Alzheimer's is the moment when a loved one struggling with the disease no longer fully recognizes a family member or close friend who is caring for them.

13 Aug 2015

Study suggests potential target for treating familial form of ALS

A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick and dies. Researchers at the NIH's National Institute of Neurological Disorders and Stroke have learned how a mutation in the gene for superoxide dismutase 1 (SOD1), which causes ALS, leads cells to accumulate damaged materials.

13 Aug 2015

McMaster University hematologist finds different limb loss syndromes

How people can develop limb gangrene and lose fingers and feet has baffled doctors for centuries. Now a McMaster University hematologist has identified different limb loss syndromes along with explanations for what is happening and what can be done about it.

13 Aug 2015

Penn Medicine experts say that health care innovation is about testing new ideas to promote better patient care

Health care has much to learn from innovative high-tech companies, but not in the way most people think, according to a Perspective published today in the New England Journal of Medicine and authored by innovation experts from the Perelman School of Medicine and the Wharton School at the University of Pennsylvania. Innovation, they say, can most effectively achieve meaningful outcomes by testing many new ideas quickly, cheaply, and contextually.

13 Aug 2015

Regular exercise benefits children with multiple sclerosis

A new study suggests children with multiple sclerosis (MS) who exercise regularly may have a less active disease. The research is published in the August 12, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Aug 2015

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

New research reveals that depressive symptoms, stress, anxiety, and anger and lack of social support in patients with rheumatoid arthritis (RA) were linked to atherosclerosis--a build-up of fatty deposits in the arteries that contributes to cardiovascular disease. The study published in Arthritis Care & Research, a journal of the American College of Rheumatology, suggests that screening and treatment of psychosocial symptoms may curb the cardiovascular disease burden in RA patients.

13 Aug 2015

BIDMC researchers examine impact of note sharing on patient safety, quality of care

Researchers from Beth Israel Deaconess Medical Center are homing in on the potential benefits of allowing patients access to the notes their clinicians write after a visit. An article published in the August edition of The Joint Commission Journal on Quality and Patient Safety suggests that this kind of patient engagement has the power to improve safety and quality of care.

13 Aug 2015

New UBC research reveals alternative route to rein in glioma cancer cells

New UBC research into brain cancer suggests treatments should target the cells around a tumor to stop it from spreading.

13 Aug 2015

Chances of survival due to chemotherapy significantly lower for older breast cancer patients

Chemotherapy prolongs life for older adults with most types of cancer, but for women over the age of 80 with breast cancer, the chances of survival due to chemotherapy are significantly lower, according to a study led by researchers from The University of Texas Health Science Center at Houston.

13 Aug 2015

Landmark study finds health disparity among children living in orphanages and extended family members

With the support of a second grant of more than $3 million from the National Institutes of Health, researchers from the Regenstrief Institute, Indiana University, Brown University, the University of Toronto, and Moi University in Eldoret, Kenya are building upon their landmark study of Kenyan orphans which found that those living in orphanages were healthier, both physically and mentally, than those living with extended family members.

13 Aug 2015

Researchers analyze inclusion/exclusion criteria used in antidepressant efficacy studies

Mark Zimmerman, M.D., a clinical researcher at Rhode Island Hospital, and his team analyzed the criteria used in antidepressant efficacy studies (AETs) and learned that the inclusion/exclusion criteria for AETs have narrowed over the past five years so that the most patients are excluded. The research was published today in Mayo Clinic Proceedings.

13 Aug 2015

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

A review of 15 years’ worth of data in a national pediatric medical database has documented a substantial increase in the rate of hospitalizations for children with a form of high blood pressure once most common in those with congenital heart disease.

13 Aug 2015

New research could help develop precision medicine for primary aldosteronism

Each of your kidneys wears a little yellow cap that helps keep your blood pressure in check, and much more. But in some people, it starts running amok, pumping out a hormone that sends blood pressure sky-high.

13 Aug 2015

High-protein breakfast prevents body fat gains, stabilizes glucose levels among overweight teens

Approximately 60 percent of young people habitually skip breakfast up to four times a week, previous research has shown. Although health experts recommend breakfast as a strategy to reduce an individual's chance of obesity, little research has examined if the actual type of breakfast consumed plays a significant role in one's health and weight management.

13 Aug 2015

Medical Research News

Molecular on-off switch controls how mouse brain responds to vision loss

Higher-fit kids have significantly thinner gray matter, better mathematics achievement than their low-fit peers

First clinical trial to test use of retinal progenitor cells for treating retinitis pigmentosa begins

New MRI contrast agent detects tiny breast cancer tumors, micrometastases

Tumor cells associated with pancreatic cancer work with each other to increase tumor spread

Study identifies two key traits involved in development of obsessive-compulsive disorder

Researchers identify novel brain network that plays wide role in memory and learning processes

Study suggests potential target for treating familial form of ALS

McMaster University hematologist finds different limb loss syndromes

Penn Medicine experts say that health care innovation is about testing new ideas to promote better patient care

Regular exercise benefits children with multiple sclerosis

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

BIDMC researchers examine impact of note sharing on patient safety, quality of care

New UBC research reveals alternative route to rein in glioma cancer cells

Chances of survival due to chemotherapy significantly lower for older breast cancer patients

Landmark study finds health disparity among children living in orphanages and extended family members

Researchers analyze inclusion/exclusion criteria used in antidepressant efficacy studies

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

New research could help develop precision medicine for primary aldosteronism

High-protein breakfast prevents body fat gains, stabilizes glucose levels among overweight teens

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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