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Researchers discover how and where chromosome fragile sites occur in human DNA

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA. These sites are frequently observed in cancer cells and are responsible for causing genomic rearrangements.

15 May 2015

Handshakes better than your blood pressure at assessing your health

The firmness of your hand grip is better than your blood pressure at assessing your health, Hamilton researchers have found, and reduced muscular strength, measured by your grip, is consistently linked with early death, disability and illness.

15 May 2015

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Army scientists working to support the Ebola virus outbreak response in West Africa have established the first genomic surveillance capability in Liberia, enabling them to monitor genetic changes in the virus within one week of sample collection. An article describing their work was recently published ahead of print in the online edition of Emerging Infectious Diseases.

15 May 2015

Regular exercise reduces mortality risk in elderly men

The results of a long-term trial show that regular exercise reduces the all-cause death rate in elderly men by 40%...

15 May 2015

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Researchers at Columbia University's Mailman School of Public Health and Leiden University in the Netherlands found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation known to suppress genes involved in growth, development, and metabolism documented at age 59.

15 May 2015

Study exposes gap in health care services provided to Medicaid enrollees

More than half of all Medicaid enrollees prefer the "one-stop shop" of a hospital emergency department to receive care for conditions that could be treated effectively at a primary care clinic, according to an article by a researcher at the University of Colorado School of Medicine on the Anschutz Medical Campus.

15 May 2015

Automated analysis of vital signs could help prevent trauma patients from life-threatening bleeding

Automated analysis of the vital signs commonly monitored in patients being transported to trauma centers could significantly improve the ability to diagnose those with life-threatening bleeding before they arrive at the hospital, potentially saving their lives.

15 May 2015

Study shows how organizational factors affect time to bring high BP under control

For medical practices, having more unique doctors on staff and having doctors see more patients doesn't necessarily lead to improved patient outcomes--and in fact, may have the opposite effect, according to a brief report in the June issue of Medical Care.

15 May 2015

Smoking-related DNA damage can be detected in cheek swabs

DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren't usually associated with it - including breast and gynaecological cancers.

15 May 2015

Acupuncture reduces pain, inflammation in pediatric patients with acute appendicitis

Acupuncture was shown to lessen pain and reduce the underlying inflammation in pediatric patients with a diagnosis of acute appendicitis, according to a study published in the Journal of Alternative and Complementary Medicine, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

15 May 2015

UMD study examines link between mental health and the Great Recession

Men and women in the U.S. had lower odds of depression diagnoses and better mental health during the Great Recession of 2007-09 compared to pre-recession according to a University of Maryland study published in the journal PLOS ONE.

15 May 2015

CCFA announces $17.5 million grant to establish Crohn's disease, ulcerative colitis research platform

The Crohn's & Colitis Foundation of America announces a three-year, $17.5 million grant from The Leona M. and Harry B. Helmsley Charitable Trust to establish an integrated knowledge platform designed to centralize and aggregate patient information - with linked biosamples - across multiple research efforts.

15 May 2015

Profiling normal DNA provides opportunity to identify inherited mutations

As the practice of genetically profiling patient tumors for clinical treatment decision making becomes more commonplace, a recent study from The University of Texas MD Anderson Cancer Center suggests that profiling normal DNA also provides an important opportunity to identify inherited mutations that could be critical for patients and their families.

15 May 2015

Patients with operable early-stage NSCLC could achieve better overall survival rates with SABR

Patients with operable stage I non-small cell lung cancer (NSCLC) could achieve better overall survival rates if treated with Stereotactic Ablative Radiotherapy (SABR) rather than the current standard of care -- invasive surgery -- according to research from a phase III randomized international study from The University of Texas MD Anderson Cancer Center.

15 May 2015

Researchers explore how low-level electrical stimulation reduces inflammation

The Feinstein Institute for Medical Research, the research arm of the North Shore-LIJ Health System, and SetPoint Medical Inc., a biomedical technology company, today released the results of research on the therapeutic potential of vagus nerve stimulation. In a paper published by Bioelectronic Medicine, Kevin J. Tracey, MD, and his colleagues at the Feinstein Institute, explore how low-level electrical stimulation interacts with the body's nerves to reduce inflammation, a fundamental goal of bioelectronic medicine.

15 May 2015

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers have identified new molecules that kill cancer cells while protecting healthy cells and that could be used to treat a variety of different cancers. The research shines a light on what happens to cells at the moment they become cancerous.

15 May 2015

Researchers report new label-free chemical imaging that provides similar information as molecular stains

Histopathology is a cornerstone of modern biomedical research. Yet, the practice of histopathology has evolved just a few times -- non-specific stains in the late 19th century, immunohistochemical staining in the mid-to-late 20th century and digital imaging/computerized analysis at the turn of the 20th century. In all cases, prepared biopsy samples are stained and examined under a light microscope.

15 May 2015

Allen Institute makes progress in brain research with launch of Allen Cell Types Database

The Allen Institute for Brain Science announced today that it is taking the first major scientific step to create a searchable standards database for the brain with the launch of the Allen Cell Types Database. This first release includes information on the location, electrical activity and shape of more than 240 neurons.

14 May 2015

Ground-breaking discovery could revolutionise lupus treatments

A ground-breaking discovery by Monash University researchers could revolutionise treatments given to lupus sufferers, saving thousands of people each year from serious illness or death caused by secondary infections.

14 May 2015

Bathing patients in common hospital soap can reduce MRSA contamination

Holding hope for a relatively inexpensive way to improve care and prevent the spread of deadly hospital-acquired infections, a new study reports that bathing patients in a common hospital soap, called chlorhexidine, was equally effective in preventing the transmission of the methicillin-resistant Staphylococcus aureus (MRSA) as the common practice of having healthcare workers avoid physical contact with the patients.

14 May 2015

Medical Research News

Researchers discover how and where chromosome fragile sites occur in human DNA

Handshakes better than your blood pressure at assessing your health

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Regular exercise reduces mortality risk in elderly men

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Study exposes gap in health care services provided to Medicaid enrollees

Automated analysis of vital signs could help prevent trauma patients from life-threatening bleeding

Study shows how organizational factors affect time to bring high BP under control

Smoking-related DNA damage can be detected in cheek swabs

Acupuncture reduces pain, inflammation in pediatric patients with acute appendicitis

UMD study examines link between mental health and the Great Recession

CCFA announces $17.5 million grant to establish Crohn's disease, ulcerative colitis research platform

Profiling normal DNA provides opportunity to identify inherited mutations

Patients with operable early-stage NSCLC could achieve better overall survival rates with SABR

Researchers explore how low-level electrical stimulation reduces inflammation

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers report new label-free chemical imaging that provides similar information as molecular stains

Allen Institute makes progress in brain research with launch of Allen Cell Types Database

Ground-breaking discovery could revolutionise lupus treatments

Bathing patients in common hospital soap can reduce MRSA contamination

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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