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University of Chicago scientists develop new technique to accurately measure epigenetic changes

One of the most widely used tools in epigenetics research - the study of how DNA packaging affects gene expression - is chromatin immunoprecipitation (ChIP), a technique that allows researchers to examine interactions between specific proteins and genomic regions. However, ChIP is a relative measurement, and has significant limitations that can lead to errors, poor reproducibility and an inability to be compared between experiments.

4 Jun 2015

Exalenz Bioscience initiates BreathID clinical study to detect primary liver cancer

Exalenz Bioscience, a leader in developing and marketing non-invasive medical devices for diagnosing and monitoring a range of gastrointestinal and liver diseases, today announced the initiation of a clinical study designed to investigate its BreathID test to non-invasively detect primary liver cancer, also known as Hepatocellular Carcinoma (HCC).

4 Jun 2015

Pediatric Sepsis diagnosed in three to five hours versus two to six days data at ASM

The data presented today demonstrate that in each of the 15 confirmed candidemia pediatric patient samples in the study, T2Candida was able to accurately identify the Candida species in three to five hours compared to two to six days for blood culture...

4 Jun 2015

Study explores 'laser welding' for sealing corneal transplants

Some 30,000 years ago, prehistoric man wielded animal bones as needles to suture otherwise lethal wounds. This tactic has been used, and improved upon, over time and remains the basis of surgical procedures conducted today. Even with radical new surgical techniques, which rely on metallic and polymeric staples or chemical adhesives to seal incisions, infection and permanent scarring remain major concerns. The success of any wound closure is entirely dependent on the physician's skill set alone.

4 Jun 2015

Penn Medicine researchers explore primary player involved in T cell exhaustion

Sometimes even cells get tired. When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop 'T cell exhaustion,' becoming less effective and losing their ability to attack and destroy the invaders of the body.

4 Jun 2015

Re-Inflating balloon after carotid stenting appears to double risk of stroke and death

Patients with severe blockages typically undergo surgery to scrape off the fatty deposits from the walls of the vessel, the preferred approach that carries notably lower stroke risk but is not recommended for people too sick to withstand traditional surgery...

4 Jun 2015

New study reports that poor sleep habits increase pain in knee OA

A new study reports that patients with knee osteoarthritis (OA) who have poor sleep habits display greater central sensitization--an amplification of clinical pain. Findings published in Arthritis Care & Research, a journal of the American College of Rheumatology, further show OA patients who catastrophize--consumed by thoughts of pain--had increased central sensitization that was associated with greater clinical pain.

4 Jun 2015

Better treatment, prevention strategies still needed for opportunistic infections related to AIDS

Although treatment advances have dramatically reduced deaths from opportunistic infections related to AIDS, a new study drawing on 30 years of data from more than 20,000 patients in San Francisco suggests there is still ample room to improve. About a third--35 percent--of AIDS patients diagnosed with their first opportunistic infection from 1997 to 2012 in that city died within five years, according to the study, published in the Journal of Infectious Diseases.

4 Jun 2015

New study examines appropriate use of dietary supplementation in children with ASD

Children with Autism Spectrum Disorder (ASD) are often picky eaters, which can lead parents to suspect that their children might not be getting adequate amounts of vitamins and minerals. This sometimes leads parents of children with ASD to try nutritional supplements and dietary regimens such as gluten-free and casein-free (GFCF) diets without professional supervision.

4 Jun 2015

Investigators patent novel technique for detecting carcinomas in oral mucosa

Malignant tumours of the oral cavity are the sixth leading cause of cancer-related deaths worldwide. As such, a fast and accurate diagnosis is key to maximising the probability of successful treatment and the hope and quality of life of patients.

4 Jun 2015

Anna Nele Meckler and Armelle Corpet to receive SNSF's 2015 Marie Heim-Vögtlin Prize

The biologist Armelle Corpet and paleo-climatologist Anna Nele Meckler will receive the 2015 Marie Heim-Vögtlin (MHV) Prize. This distinction rewards their remarkable scientific work supported by a MHV grant. The prize will be bestowed on 23 September 2015 at the Swiss National Science Foundation.

4 Jun 2015

New strategy involving three-pronged approach may keep lung cancer aside

Lung cancer is the leading cause of cancer death worldwide, responsible for some 1.59 million deaths a year. That figure is due, in part, to the fact that lung cancer often returns after what seems at first to be successful treatment. However, the recurring cancer is often resistant to the chemotherapy and other drugs that originally drove it into remission.

4 Jun 2015

People with high moral reasoning skills show increased gray matter in brain

Individuals with a higher level of moral reasoning skills showed increased gray matter in the areas of the brain implicated in complex social behavior, decision making, and conflict processing as compared to subjects at a lower level of moral reasoning, according to new research from the Perelman School of Medicine and the Wharton School of the University of Pennsylvania in collaboration with a researcher from Charité Universitätsmediz in Berlin, Germany.

4 Jun 2015

Steven Schiff wins NIH Director's Pioneer Award to reduce infant deaths from neonatal sepsis

Steven Schiff, professor of neurosurgery and Brush Chair Professor of Engineering in Engineering Science and Mechanics, has received a $4.1 million National Institutes of Health Director's Pioneer Award, for research aimed at reducing the number of infant deaths from neonatal sepsis in developing countries by identifying the roots of infection, from season of birth to home environment.

4 Jun 2015

Duke Medicine scientists produce 3-D map of human brain stem using MRI technology

Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology.

4 Jun 2015

Wistar Institute scientists find new biomarker that appears to be more accurate at detecting NSCLC

Survival rates for patients with lung cancer increase dramatically the earlier the disease is diagnosed, underscoring the need for effective biomarkers that can be used for detection. Now, scientists at The Wistar Institute have found a protein that circulates in the blood that appears to be more accurate at detecting non-small cell lung cancer (NSCLC) than currently available methods used for screening.

4 Jun 2015

'SpinDrops' app provides insight into the quantum properties of coupled nuclear spins

Magnetic resonance tomography (MRT) images are an important diagnostic tool. The achievable contrast depends on how well the nuclear spins that form the basis of the imaging signals can be controlled. Mathematically, the properties of nuclear spins are described by special matrices.

4 Jun 2015

Scientists make breakthrough in schizophrenia research

An international team of scientists led by Cardiff University researchers has provided the strongest evidence yet of what causes schizophrenia - a condition that affects around 1% of the global population.

4 Jun 2015

Blood research could improve treatment for injured soldiers on the battlefield

Blood research conducted by biomedical engineers from The University of Texas at San Antonio College of Engineering, in collaboration with the Blood Research Program of the U.S. Army Institute of Surgical Research, could change the way injured soldiers are treated on the battlefield.

4 Jun 2015

Newly discovered nerve cells trigger locomotion, supply the brain with speed-related information

Scientists at the German Center for Neurodegenerative Diseases and the University of Bonn led by Prof. Stefan Remy report on this in the journal "Neuron". Their investigations give new insights into the workings of spatial memory. Furthermore, they could also help improve our understanding of movement related symptoms associated with Parkinson's disease.

4 Jun 2015

Medical Research News

University of Chicago scientists develop new technique to accurately measure epigenetic changes

Exalenz Bioscience initiates BreathID clinical study to detect primary liver cancer

Pediatric Sepsis diagnosed in three to five hours versus two to six days data at ASM

Study explores 'laser welding' for sealing corneal transplants

Penn Medicine researchers explore primary player involved in T cell exhaustion

Re-Inflating balloon after carotid stenting appears to double risk of stroke and death

New study reports that poor sleep habits increase pain in knee OA

Better treatment, prevention strategies still needed for opportunistic infections related to AIDS

New study examines appropriate use of dietary supplementation in children with ASD

Investigators patent novel technique for detecting carcinomas in oral mucosa

Anna Nele Meckler and Armelle Corpet to receive SNSF's 2015 Marie Heim-Vögtlin Prize

New strategy involving three-pronged approach may keep lung cancer aside

People with high moral reasoning skills show increased gray matter in brain

Steven Schiff wins NIH Director's Pioneer Award to reduce infant deaths from neonatal sepsis

Duke Medicine scientists produce 3-D map of human brain stem using MRI technology

Wistar Institute scientists find new biomarker that appears to be more accurate at detecting NSCLC

'SpinDrops' app provides insight into the quantum properties of coupled nuclear spins

Scientists make breakthrough in schizophrenia research

Blood research could improve treatment for injured soldiers on the battlefield

Newly discovered nerve cells trigger locomotion, supply the brain with speed-related information

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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