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Findings may explain why HIV cure strategies have failed

A major hurdle to curing people of HIV infection is the way the virus hides in a reservoir composed primarily of dormant immune cells.

2 Mar 2015

New algorithm can gauge long-term death risk based on treadmill exercise performance

Analyzing data from 58,000 heart stress tests, Johns Hopkins cardiologists report they have developed a formula that estimates one's risk of dying over a decade based on a person's ability to exercise on a treadmill at an increasing speed and incline.

2 Mar 2015

Scientists discover amyloid accumulation in young human brains

Amyloid -- an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease -- starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined, reports a surprising new Northwestern Medicine study.

2 Mar 2015

Study: African Americans who moved from the South during Great Migration face shorter life expectancy

Millions of African Americans moved from the South in the early 20th century to seek better job opportunities and higher wages, but a new study on the historic Great Migration shows that with improved economic conditions came a greater risk of mortality.

28 Feb 2015

ACHA reports that nearly 2 million adults living with CHD in the U.S.

At one time, many children born with congenital heart disease (CHD) suffered from issues that carried fatal prognoses.

28 Feb 2015

Culture conditions in which stem cells are grown can affect genetic stability

The therapeutic promise of human stem cells is indisputably huge, but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities.

28 Feb 2015

Study could help boost suicide prevention efforts in the U.S.

A study that could help to bolster suicide prevention efforts has examined the prevalence of suicidal ideation and suicide attempts among adults who reported psychotic experiences.

28 Feb 2015

Routledge Journals' new special issue focuses on CFS, ME/CFS and ME research

Routledge Journals is pleased to announce a new Special Issue from the Journal of Prevention & Intervention in the Community exploring topics and constructs that could help clarify uncertainties surrounding Chronic Fatigue Syndrome (CFS), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), or Myalgic Encephalomyelitis (ME) research.

28 Feb 2015

Insurance status linked to patient safety, quality of care for patients with brain tumors

Patients that are on Medicaid or uninsured have higher rates of reportable patient safety and quality of care issues during hospitalization for brain tumors, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

28 Feb 2015

Researchers solve secret of mysterious reverse-wired eyeball

From a practical standpoint, the wiring of the human eye - a product of our evolutionary baggage - doesn't make a lot of sense. In vertebrates, photoreceptors are located behind the neurons in the back of the eye - resulting in light scattering by the nervous fibers and blurring of our vision.

28 Feb 2015

Researchers investigate efficiency of drug research and development

Drug R&D costs have increased substantially in recent decades, while the number of new drugs has remained fairly constant, leading to concerns about the sustainability of drug R&D and question about the factors that could be responsible.

28 Feb 2015

New book provides in-depth, advanced understanding of Ebola and rabies viruses

Significant human and animal pathogens remain major scourges to human health. Recent devastating Ebola virus disease outbreak in West Africa underscores the importance of understanding the biology of replication and response of host cells to infection by these pathogens.

28 Feb 2015

Authors examine potential reasons for the persistence of FC, other autism fads

The communication struggles of children with autism spectrum disorder can drive parents and educators to try anything to understand their thoughts, needs and wants. Unfortunately, specialists in psychology and communication disorders do not always communicate the latest science so well.

28 Feb 2015

Genetic decanalization can lead to complex genetic diseases in humans

The information encoded in the DNA of an organism is not sufficient to determine the expression pattern of genes. This fact has been known even before the discovery of epigenetics, which refers to external modifications to the DNA that turn genes "on" or "off".

28 Feb 2015

Early intervention with GLP-1 analogues may delay onset of type 2 diabetes

GLP-1 is a hormone that regulates glucose levels in the body by stimulating the secretion of insulin, and GLP-1 also inhibits appetite. "We have found that GLP-1 is reduced by up to 25% among people with pre-diabetes and up to 20% among obese people compared to normal weight people.

28 Feb 2015

Study: Competition among physicians, retail medical clinics increases antibiotic prescriptions

Competition among doctors' offices, urgent care centers and retail medical clinics in wealthy areas of the U.S. often leads to an increase in the number of antibiotic prescriptions written per person, a team led by Johns Hopkins researchers has found.

28 Feb 2015

Findings reveal variations between countries and regions in use of HSCT procedure

Since the first experimental bone marrow transplant over 50 years ago, more than one million hematopoietic stem cell transplantations (HSCT) have been performed in 75 countries, according to new research charting the remarkable growth in the worldwide use of HSCT, published in The Lancet Haematology journal.

28 Feb 2015

Steep Hill plans to open laboratory for testing quality of medical cannabis

Steep Hill, the industry leader in cannabis testing and analytics in the US and internationally, intends to open a full service medical cannabis quality assurance laboratory in Albuquerque, New Mexico, bringing advanced scientific tools and methodology to the state, for regulatory oversight of cannabis.

28 Feb 2015

Two cancer centres partner to advance personalized therapies against cancer

Two internationally acclaimed cancer centres today announced a partnership to accelerate academic and clinical research to advance personalized, targeted therapies against cancer.

28 Feb 2015

Researchers successfully convert adult human skin cells into neurons that control appetite

Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight control and testing new therapies for obesity.

28 Feb 2015