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'Bioequivalence' shown for generic lamotrigine

The EQUIGEN trial shows that switching to and between generic versions of lamotrigine does not affect the plasma levels achieved by patients with epilepsy.

17 Feb 2016

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

A reduction in the risks of infection- and organ failure-related death has driven an improvement in non-relapse mortality among recipients of allogeneic haematopoietic stem cell transplantation, Japanese research suggests.

17 Feb 2016

Mtss1 'tumour suppressor' for CML

The metastasis suppressor 1 protein acts a tumour suppressor in chronic myeloid leukaemia stem cells, reveals research published in Leukemia.

17 Feb 2016

Researchers reveal how brain-specific microRNA plays key role in causing abnormal brain development

Autism Spectrum Disorders (ASDs) are a group of highly inheritable behavioural disorders that pose major personal and public health concerns. Patients with ASDs have mild to severe communication difficulties, repetitive behaviour and social challenges. Such disorders significantly challenge an individual's ability to conduct daily activities and function normally in society. Currently there are very few medication options that effectively treat ASDs.

17 Feb 2016

Graphic anti-smoking images can warn smokers about cigarettes' health consequences

Viewing graphic anti-smoking images on cigarette packs triggers activity in brain areas involved in emotion, decision-making and memory as observed via brain scans.

17 Feb 2016

Studies explore causative factor of hypertension in younger, obese men and women

There's no doubt estrogen plays a big role in the differences between males and females, and now researchers want to know if it also helps explain emerging sex differences in what makes younger, obese men and women hypertensive.

17 Feb 2016

Tackling antibiotic resistance from a new perspective

Tackling antibiotic resistance on only one front is a waste of time because resistant genes are freely crossing environmental, agricultural and clinical boundaries, new research has shown.

17 Feb 2016

Early life factors contribute to aging of lungs

Smoking mothers, respiratory infections and the date you were born contribute to determine how fast your lungs are aging.

17 Feb 2016

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

In patients with coronary heart disease requiring a stent implantation, the benefit of treatment with antibody-coated drug-eluting stents (ABC-DES) versus drug-eluting stents without antibody coating (DES) is still unclear.

17 Feb 2016

Patterns of philopatry and longevity contribute to menopause, study suggests

The evolution of the menopause was 'kick-started' by a fluke of nature, but then boosted by the tendency for sons and grandsons to remain living close to home, a new study by Liverpool scientists suggests.

17 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Study: Many school children avoid basic foods due to perceived hypersensitivity

A study on hypersensitivity to the basic foods milk, egg, fish and wheat among young school children showed that reported food hypersensitivity was eight times more common than allergies confirmed by allergy tests. This according to a new dissertation at Umeå University.

17 Feb 2016

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

A study led by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key player contributing to the maintenance of hematopoietic stem cells (HSCs), blood cell precursors which have the ability to become any type of blood cell in the body.

17 Feb 2016

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Fast metastasis and resistance to treatment are characteristic of aggressive types of cancer such as pancreatic cancer and certain kinds of breast cancer. They are also the main causes of cancer-related death, as there is currently no specific treatment available that is able to stop tumours spreading throughout the whole body. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have recently made a discovery that could change this.

17 Feb 2016

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching inhibitors of signal transducer and activator of transcription (STAT3), a protein that controls transcription by the STAT3 gene.

17 Feb 2016

Small chemical change to existing antibacterial drug may result in better treatment for TB

Researchers with Vanderbilt University have discovered that one small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis.

17 Feb 2016

High salt and sodium intake persists in China: Study

Yongning Wu, Ph.D., of the China National Centre for Food Safety Risk Assessment, Beijing, China, and colleagues compared salt and sodium consumption in China in 2000 with 2009-2012. The study appears in the February 16 issue of JAMA.

17 Feb 2016

First-of-its-kind project focuses on farming communities and dementia

Dementia is a growing health problem, with an anticipated increase in the number of cases in the UK of 156 per cent between now and 2051, according to statistics from the Alzheimer's Society.

17 Feb 2016

Current evidence insufficient to assess benefits and harms of screening for ASD

The U.S. Preventive Services Task Force has concluded that the current evidence is insufficient to assess the balance of benefits and harms of screening for autism spectrum disorder (ASD) in children 18 to 30 months of age for whom no concerns of ASD have been raised by their parents or a clinician.

17 Feb 2016

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Potsdam-Rehbruecke - Like sucrose (table sugar), the natural disaccharide isomaltulose (PalatinoseTM) consists of glucose and fructose, but it is apparently more suitable for people with type 2 diabetes with regard to regulating blood glucose levels.

17 Feb 2016

Medical Research News

'Bioequivalence' shown for generic lamotrigine

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

Mtss1 'tumour suppressor' for CML

Researchers reveal how brain-specific microRNA plays key role in causing abnormal brain development

Graphic anti-smoking images can warn smokers about cigarettes' health consequences

Studies explore causative factor of hypertension in younger, obese men and women

Tackling antibiotic resistance from a new perspective

Early life factors contribute to aging of lungs

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

Patterns of philopatry and longevity contribute to menopause, study suggests

New optogenetic technology could turn on immune cells to attack melanoma tumors

Study: Many school children avoid basic foods due to perceived hypersensitivity

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

Small chemical change to existing antibacterial drug may result in better treatment for TB

High salt and sodium intake persists in China: Study

First-of-its-kind project focuses on farming communities and dementia

Current evidence insufficient to assess benefits and harms of screening for ASD

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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