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Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

For hikers, football players, endurance athletes, and a growing range of elite and recreational exercisers, the best approach to preventing potentially serious reductions in blood sodium level is to drink when thirsty, according to an updated consensus statement on exercise-associated hyponatremia (EAH).

30 Jun 2015

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

An analysis of the results of more than 16,000 brain and spine surgeries suggests patients have nothing to fear from having residents — physicians-in-training — assist in those operations.

30 Jun 2015

Neighborhood physical and social environments may affect type 2 diabetes risk

Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine.

30 Jun 2015

Study may lead to better treatments for children with neuroblastoma

Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.

30 Jun 2015

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.

30 Jun 2015

Danish scientists discover what controls ADAM17 enzyme that aids growth of cancer tumours

Researchers from the University of Copenhagen have discovered what regulates an enzyme that is central to the growth of cancer tumours. This could be of great value to future cancer treatment.

30 Jun 2015

TSRI-led study identifies new immune molecules that protect against Marburg virus

A new study led by scientists at The Scripps Research Institute identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks.

30 Jun 2015

Researchers discover gene locations affecting wrist bones in children

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.

30 Jun 2015

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Inhibikase Therapeutics, Inc. announces the receipt of a Phase II SBIR grant in the amount of $1.54 million dollars from the U.S. National Institutes of Health to advance its novel Re-engineering with Metabolism Preserved (RAMP) medicinal chemistry program.

29 Jun 2015

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ.

29 Jun 2015

Can-Fite reports further progress in continuing preclinical program of CF602 sexual dysfunction drug

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, today reported further progress in its continuing preclinical program of its CF602 drug candidate as the Company prepares to file an investigational new drug (IND) application with the U.S. Food and Drug Administration to allow the initiation of a Phase I clinical study.

29 Jun 2015

Scientists examine rates of secondary mutations in biomarker genes

Many tests for predictive biomarkers in tumors focus on selected known mutations or regions (e.g. hotspot panels). In a new study, scientists at Molecular Health examined the rates of secondary mutations in known biomarker genes and their potential impact on the diagnostic reliability of specific single-nucleotide variant (SNV) biomarker testing.

29 Jun 2015

Researchers reconstruct infants' visual perception of the world

A newborn infant can see its parents' expressions at a distance of 30 cm. For the first time researchers have managed to reconstruct infants visual perception of the world.

29 Jun 2015

People with specific gene variant at greater risk of developing depressions

People born with a particular gene variant have a greater risk of developing depressions, a recent study from the Department of Psychology at The University of Oslo shows.

29 Jun 2015

Study opens up new line of research into origin of digestive diseases

There are numerous studies related to the absorption of nutrients from the stomach since understanding what happens in our digestive system is crucial, for example, in order to be able to avoid in the future some of the diseases that affect part of the population to a lesser or greater extent.

29 Jun 2015

New 3-step solution could help parents banish their children's fussy eating habits

Parents could banish their children's fussy eating habits by following three simple steps, a new study suggests. Introducing the 'three Rs' - Repetition, Role Modelling and Rewards - at meal times could help parents to get their children to eat, and even like, new vegetables, according to new research from Aston and Loughborough Universities.

29 Jun 2015

Egalet reports positive results from Category 3 abuse-deterrent intranasal HAL study

Egalet Corporation today announced positive results from a Category 3 intranasal human abuse liability (HAL) study of Egalet-001, an abuse-deterrent, extended-release, oral morphine formulation in late-stage clinical development for the management of pain severe enough to require daily, around-the-clock opioid treatment and for which alternative treatments are inadequate.

29 Jun 2015

Scientists identify association between coronary heart disease and osteoporosis

University of Southampton scientists have discovered a link between coronary heart disease and osteoporosis, suggesting both conditions could have similar causes.

29 Jun 2015

Study: Umbilical cord milking improves blood pressure, red blood cell levels in preterm infants

A technique to increase the flow of blood from the umbilical cord into the infant's circulatory system improves blood pressure and red blood cell levels in preterm infants delivered by Cesarean section, according to a study funded by the National Institutes of Health.

29 Jun 2015

Six Catalonia research centres collaborate to set up The Barcelona Institute of Science and Technology

Six of the top research centres in Catalonia have taken a step forward in their collaboration by setting up The Barcelona Institute of Science and Technology. The centres involved are: the Centre for Genomic Regulation; the Institute of Chemical Research of Catalonia; the Catalan Institute for Nanoscience and Nanotechnology; the Institute of Photonic Sciences; the High Energy Physics Institute; and the Institute for Research in Biomedicine.

27 Jun 2015

Medical Research News

Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

Neighborhood physical and social environments may affect type 2 diabetes risk

Study may lead to better treatments for children with neuroblastoma

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Danish scientists discover what controls ADAM17 enzyme that aids growth of cancer tumours

TSRI-led study identifies new immune molecules that protect against Marburg virus

Researchers discover gene locations affecting wrist bones in children

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Researchers discover mechanism that regulates metabolism

Can-Fite reports further progress in continuing preclinical program of CF602 sexual dysfunction drug

Scientists examine rates of secondary mutations in biomarker genes

Researchers reconstruct infants' visual perception of the world

People with specific gene variant at greater risk of developing depressions

Study opens up new line of research into origin of digestive diseases

New 3-step solution could help parents banish their children's fussy eating habits

Egalet reports positive results from Category 3 abuse-deterrent intranasal HAL study

Scientists identify association between coronary heart disease and osteoporosis

Study: Umbilical cord milking improves blood pressure, red blood cell levels in preterm infants

Six Catalonia research centres collaborate to set up The Barcelona Institute of Science and Technology

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