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Study: Gene variant linked to increased risk of vincristine-induced peripheral neuropathy in children

Children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug vincristine, according to a study in the February 24 issue of JAMA.

25 Feb 2015

Study finds new approaches to manage anticoagulant-associated intracerebral hemorrhage

Among patients with oral anticoagulation-associated intracerebral hemorrhage (bleeding within the brain), reversal of international normalized ratio (INR; a measure used to determine the clotting tendency of blood while on medication) below a certain level within 4 hours and systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of hematoma (a localized swelling filled with blood) enlargement, and resumption of anticoagulant therapy was associated with a lower risk of ischemic events without increased bleeding complications, according to a study in the February 24 issue of JAMA.

25 Feb 2015

Direct brain responsive neurostimulator reduces seizures, improves quality of life

Piotr Olejniczak, MD, PhD, LSU Health New Orleans Professor of Neurology and Director of the Epilepsy Center, contributed to a study of the long-term effectiveness of the first direct brain responsive neurostimulator for partial onset, or focal, seizures that cannot be controlled with medication.

25 Feb 2015

Three innovative research projects aim to improve lives of people with mobility difficulties

A prosthetic hand controlled by the nervous system, robotic clothing to help people with walking, and biosensors to monitor how patients use equipment or exercise during rehabilitation are the focus of three research projects awarded £5.3 million by the Engineering and Physical Sciences Research Council.

25 Feb 2015

People who use snus are at increased risk of developing alcohol dependency

People who use snus run twice the risk of developing alcohol dependency compared with non-users, and the more one uses snus, the higher the risk. This has been found in a study from Umeå University which was published in the journal Drug and Alcohol Dependence.

25 Feb 2015

Jiraffe introduces new improved white Multistander frame

Jiraffe, UK distributors of innovative postural support and service products, has introduced an improved white Multistander to its popular range of products from Jenx Ltd.

25 Feb 2015

Discovery demonstrates effect of exercise to prevent chronic health conditions

A researcher at the University of Virginia School of Medicine has magnified a benefit of exercise in mice to provide a "profound" protection from diabetic cardiomyopathy, a potentially deadly heart condition that affects many people with diabetes. The discovery demonstrates the power of exercise to prevent chronic health conditions and suggests that one day some benefits of exercise may come in a pill or bottle.

25 Feb 2015

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Vasospasm, or severe narrowing of blood vessels, is a dangerous complication observed in children with moderate to severe traumatic brain injury. In a paper recently published in Critical Care Medicine, investigators at Nationwide Children's Hospital have further defined the prevalence, associated factors and time course for vasospasm in children with these brain injuries.

25 Feb 2015

Garlic compound can help fight lung infections in people with cystic fibrosis

A chemical found in garlic can kill bacteria that cause life-threatening lung infections in people with cystic fibrosis, research suggests.

25 Feb 2015

Filipino women who move to Canada face breast cancer risk at younger age

Filipinos who move to Canada are diagnosed with breast cancer at a younger age than women from other parts of East Asia or Caucasians, new research has found.

25 Feb 2015

Study shows that even breast cancers with few androgen receptors benefit from anti-androgen therapy

A University of Colorado Cancer Center study published today in the journal Molecular Cancer Therapeutics shows that only about 1 percent of triple-negative breast cancer cells in a tumor must be "androgen-receptor-positive" to show benefit from anti-androgen therapies.

25 Feb 2015

Teen girls from rural areas have undiagnosed asthma, face higher risk of depression

Teen girls who live in rural areas are more likely than their male counterparts to have undiagnosed asthma, and they often are at a higher risk of depression, according to researchers at the Medical College of Georgia at Georgia Regents University.

25 Feb 2015

Patients with symptoms of mental illness less likely to receive advice from health care providers

More than half of patients with symptoms of mental illness - and nearly one-third of those who also had diabetes - said their health care providers had never told them to exercise or reduce their intake of dietary fat, according to a new study published in Diabetes Educator.

25 Feb 2015

Changes to DNA sequence associated with peanut allergy

Research funded by the National Institutes of Health suggests that changes in a small region of chromosome 6 are risk factors for peanut allergy in U.S. children of European descent. The genetic risk area is located among two tightly linked genes that regulate the presentation of allergens and microbial products to the immune system. This study is the first to use a genome-wide screening approach in patients with well-defined food allergy to identify risks for peanut allergy.

25 Feb 2015

PCORI funds five patient-centered comparative effectiveness research studies

The Patient-Centered Outcomes Research Institute Board of Governors today approved awards totaling more than $64 million to fund five large patient-centered comparative effectiveness research (CER) studies that will answer critical clinical questions about care for cancer, back pain, and stroke.

25 Feb 2015

PCF announces Challenge Awards to support research on new treatment strategies for prostate cancer

The Prostate Cancer Foundation (PCF) announces 3 new Challenge Awards to support discoveries for the treatment of lethal prostate cancer.

25 Feb 2015

Serous ovarian cancer is more deadly, shows Cancer Research UK study

THE most common type of ovarian cancer is more deadly if it consists of a patchwork of different groups of cells, according to a Cancer Research UK study published today (Tuesday) in PLOS Medicine.

25 Feb 2015

Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Public health experts have long known that tobacco smoke exposure (TSE) can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth.

24 Feb 2015

Developments in ChIP technology

Biowales, one of the UK’s leading events for the life sciences sector, this year will focus on the life sciences supply chain providing practical commercial opportunities for growth through novel routes to market in the private sector and National Health Service (NHS).

From Chromatrap® - Porvair Sciences Ltd 24 Feb 2015

Researchers identify first genetic variation linked to increased risk of peripheral neuropathy

Researchers have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used anti-cancer drug. Investigators also found evidence of how it may be possible to protect young leukemia patients without jeopardizing cures.

24 Feb 2015

Medical Research News

Study: Gene variant linked to increased risk of vincristine-induced peripheral neuropathy in children

Study finds new approaches to manage anticoagulant-associated intracerebral hemorrhage

Direct brain responsive neurostimulator reduces seizures, improves quality of life

Three innovative research projects aim to improve lives of people with mobility difficulties

People who use snus are at increased risk of developing alcohol dependency

Jiraffe introduces new improved white Multistander frame

Discovery demonstrates effect of exercise to prevent chronic health conditions

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Garlic compound can help fight lung infections in people with cystic fibrosis

Filipino women who move to Canada face breast cancer risk at younger age

Study shows that even breast cancers with few androgen receptors benefit from anti-androgen therapy

Teen girls from rural areas have undiagnosed asthma, face higher risk of depression

Patients with symptoms of mental illness less likely to receive advice from health care providers

Changes to DNA sequence associated with peanut allergy

PCORI funds five patient-centered comparative effectiveness research studies

PCF announces Challenge Awards to support research on new treatment strategies for prostate cancer

Serous ovarian cancer is more deadly, shows Cancer Research UK study

Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Developments in ChIP technology

Researchers identify first genetic variation linked to increased risk of peripheral neuropathy

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