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Johns Hopkins researchers develop method to turn stem cells into retinal ganglion cells

Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain. Death and dysfunction of these cells cause vision loss in conditions like glaucoma and multiple sclerosis.

1 Dec 2015

Mutant protein responsible for cystic fibrosis talks to wrong cellular neighbors

Scientists at The Scripps Research Institute have found evidence that a mutant protein responsible for most cases of cystic fibrosis is so busy "talking" to the wrong cellular neighbors that it cannot function normally and is prematurely degraded.

1 Dec 2015

DNA sequence variation can influence gene activity in developing human brain

An international research collaboration has shed new light on how DNA sequence variation can influence gene activity in the developing human brain.

1 Dec 2015

Air evacuations may pose significant added risk to patients with traumatic brain injury

Over the past 15 years, more than 330,000 U.S. soldiers have suffered a traumatic brain injury (TBI). It is one of the leading causes of death and disability connected to the country's recent conflicts in Afghanistan and Iraq. Many of these patients were evacuated by air from these countries to Europe and the U.S. for further treatment. In general, these patients were flown quickly to hospitals outside the battle zone, where more extensive treatment was available.

1 Dec 2015

New study compares outcomes from two postoperative pain control methods in knee replacement patients

A new study published today in The Journal of the American Osteopathic Association compared outcomes from two types of postoperative pain control methods in a group of patients who had both of their knees replaced.

1 Dec 2015

MPP collaborates with University of Liverpool to accelerate development of HIV nanomedicines

The Medicines Patent Pool today announced a collaboration with the University of Liverpool and a licence for the university's Solid Drug Nanoparticle (SDN) technology to accelerate the development of WHO-recommended antiretrovirals as nanomedicines.

30 Nov 2015

Surgeons’ contralateral breast cancer knowledge gaps identified

A survey of US surgeons reveals the gaps in the respondents’ knowledge of contralateral breast cancer risk.

30 Nov 2015

New study: Are GPs over prescribing sleeping tablets?

The team at SleepCogni are dedicated to changing the nations’ sleep habits and conducted an independent study in October 2015 to give a snapshot view of current sleep behaviour.

30 Nov 2015

Pre-existing asthma may strongly predict future chronic migraine attacks

Pre-existing asthma may be a strong predictor of future chronic migraine attacks in individuals experiencing occasional migraine headaches, according to researchers from the University of Cincinnati, Montefiore Headache Center and Albert Einstein College of Medicine, and Vedanta Research.

30 Nov 2015

Research sheds light on genetic factors involved in autoimmune diseases

A collaboration between researchers at the Babraham Institute and the University of Manchester has mapped the physical connections occurring in the genome to shed light on the parts of the genome involved in autoimmune diseases. Using a new technique, called Capture Hi-C, the team revealed novel insights into how changes in the genetic sequence have a biological effect and increase the risk of disease.

30 Nov 2015

Medical professionals compare different treatment methods for Neuromyelitis optica

In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy. Under the auspices of the Ruhr-Universität Bochum and the Hannover Medical School, the team published their findings in the journal Annals of Neurology.

30 Nov 2015

Scientists discover genetic causes of Goldenhar syndrome

Some children are born with cleft palates and, of those children, some have an asymmetrical face and a malformed ear. A team of scientists led by Berlin-based researcher Enno Klußmann of the Max Delbrück Center for Molecular Medicine has taken an important step towards discovering the genetic causes of this condition, known as Goldenhar syndrome.

30 Nov 2015

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

In addition to their well established cholesterol lowering benefits, statins also have potent anti-inflammatory, anti-fibrotic and antioxidant effects, which continue to be identified in a wide range of diseases.

30 Nov 2015

Researchers discover drug target and genetic pathway for graft-versus-host disease

A Seattle Children's Research Institute lab has discovered a genetic pathway that can be targeted with existing drugs to prevent graft-versus-host disease (GVHD), a common and deadly complication of bone marrow transplants.

30 Nov 2015

Heptares announces strategic drug discovery collaboration with Pfizer

Heptares Therapeutics, the clinical-stage GPCR structure-guided drug discovery and development company and wholly-owned subsidiary of Sosei Group Corporation, announces that it has entered into a strategic drug discovery collaboration with Pfizer Inc. to research and develop potential new medicines directed at up to 10 G protein-coupled receptor (GPCR) targets across multiple therapeutic areas.

30 Nov 2015

BRCA1 depletion can potentially contribute to cognitive deficits in Alzheimer's disease

Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease.

30 Nov 2015

Study analyzes effect of music therapy on palliative care patients

Music therapy can enhance terminally ill patients' wellbeing and relaxation. This treatment has been known since the 1970s, but there is little scientific research on the subject. A recent randomized controlled trial by Marco Warth et al. in Deutsches Ärzteblatt International (Dtsch Arztebl Int 2015; 112: 788-94) analyzes the effect of music therapy on palliative care patients.

30 Nov 2015

Medical Research News

Johns Hopkins researchers develop method to turn stem cells into retinal ganglion cells

Mutant protein responsible for cystic fibrosis talks to wrong cellular neighbors

DNA sequence variation can influence gene activity in developing human brain

Air evacuations may pose significant added risk to patients with traumatic brain injury

New study compares outcomes from two postoperative pain control methods in knee replacement patients

MPP collaborates with University of Liverpool to accelerate development of HIV nanomedicines

Surgeons’ contralateral breast cancer knowledge gaps identified

New study: Are GPs over prescribing sleeping tablets?

Pre-existing asthma may strongly predict future chronic migraine attacks

Research sheds light on genetic factors involved in autoimmune diseases

Medical professionals compare different treatment methods for Neuromyelitis optica

Scientists discover genetic causes of Goldenhar syndrome

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

Researchers discover drug target and genetic pathway for graft-versus-host disease

Heptares announces strategic drug discovery collaboration with Pfizer

BRCA1 depletion can potentially contribute to cognitive deficits in Alzheimer's disease

Study analyzes effect of music therapy on palliative care patients

New research reveals how gaps between gene interactions influence disease risk

Testosterone treatment can benefit men with Type 2 diabetes

Concussed athletes in clinical recovery experience neurophysiological abnormalities

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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