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Study provides new insights into early events that shape cancer

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of data collected from over 100 cell types - the research team found that the unique genetic landscape of a particular tumor could be used to predict that tumor's cell type of origin.

19 Feb 2015

Particle sciences manufactures clinical supplies for Kinex’s glioblastom therapeutic

Particle Sciences, Inc (PSI), has completed the manufacturing of clinical supplies for the first in human studies of KX2-361 (KX02), Kinex Pharmaceuticals’ small molecule Src/pre-tublin inhibitor.

19 Feb 2015

University of Alberta researcher named winner of A.S.P.E.N.'s 2015 Harry M. Vars Award

David Lim, MD, CM, of the University of Alberta has been named the winner of the 2015 Harry M. Vars Award by the American Society for Parenteral and Enteral Nutrition. The award is for his research on parenteral nutrition associated liver disease (PNALD) in infants, which was presented at A.S.P.E.N.'s Clinical Nutrition Week conference in Long Beach, California, February 14 to 17.

19 Feb 2015

Researchers find potential new target to treat asthma patients

Researchers have found a potential new target for treating asthma, according to a study led by researchers at the University of Colorado School of Medicine at the Anschutz Medical Campus and published in the journal Nature Communications.

19 Feb 2015

Possible cause of liver disease identified in adolescents with cystic fibrosis

A professor at the University of Colorado School of Medicine at the Anschutz Medical Campus and his colleagues have found a possible cause of liver disease in adolescents with cystic fibrosis.

19 Feb 2015

UT Dallas study reports new gene therapy approach

Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.

19 Feb 2015

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Nicotine's primary metabolite supports learning and memory by amplifying the action of a primary chemical messenger involved in both, researchers report.

19 Feb 2015

Study examines relationship between substance use and teen pregnancy

New research from The University of Texas at Austin suggests that many teenagers, especially younger teens, may not be getting the message about the risks of using alcohol and other drugs during pregnancy -- but that having involved parents and being engaged academically can help.

19 Feb 2015

Study findings could lead to new potential drug targets for allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs.

19 Feb 2015

INRS researchers explore cellular and molecular mechanisms that affect AgNP particles

Whereas resistance to antibiotics complicates certain treatments, antimicrobial silver nanoparticles (AgNP) are gaining popularity for medical use. These particles are toxic for certain bacteria, but what about for humans? Researchers at INRS-Institut Armand-Frappier Research Centre have taken a step toward understanding the cellular and molecular mechanisms that affect these particles.

19 Feb 2015

NIAID expands Tuberculosis Research Units program to drive innovation in TB research

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is expanding its Tuberculosis Research Units program in an effort to drive innovation in tuberculosis (TB) research. NIAID is awarding up to $15.2 million in fiscal year 2015 and as much as $105.3 million over seven years to fund four institutions that will act as a collaborative TBRU network.

19 Feb 2015

Duke researchers demonstrate genetic therapeutic technique to treat DMD patients

Duke researchers have demonstrated a genetic therapeutic technique that has the potential to treat more than half of the patients suffering from Duchenne Muscular Dystrophy (DMD).

19 Feb 2015

Weill Cornell receives NIH grant to study TB-causing bacteria

In an effort to stop tuberculosis (TB) from becoming progressively less treatable worldwide, the National Institutes of Health has awarded Weill Cornell Medical College more than $6.2 million in first-year funding to support a research collaboration among six institutions in close alliance with voluntary pharmaceutical partners.

19 Feb 2015

New plant-derived agent protects skin from harmful effects of UV irradiation

The skin is constantly challenged, and very often harmed, by environmental stressors such as UV radiation and chemicals. To cope with UV radiation, various skin cells have evolved a complex protective antioxidant defense system.

19 Feb 2015

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

Scientists have created a new molecule that shows promise for controlling HIV without daily antiretroviral drugs. The molecule foils a wider range of HIV strains in the laboratory than any known broadly neutralizing HIV antibody and is more powerful than some of the most potent of these antibodies.

19 Feb 2015

Ranibizumab drug reverses diabetes-related blindness

Ranibizumab, a prescription drug commonly used to treat age-related vision loss, also reverses vision loss caused by diabetes among Hispanic and non-Hispanic whites, according to a new study led by investigators from the University of Southern California Eye Institute.

19 Feb 2015

Rutgers researchers study rare form of gum disease that affects African-American adolescents

Oral biologist Daniel H. Fine and his team at Rutgers School of Dental Medicine have tracked more than 2,500 Newark children since 2007 to chart the progression of a rare form of gum disease that afflicts African-American adolescents.

19 Feb 2015

Researchers assemble comprehensive map of human epigenome

Virtually every cell in the body carries an identical genome. But how is it possible that each of the body's 200 different types of specialized cells - in the heart, brain, bone, skin and elsewhere - develops from the same DNA instruction book?

19 Feb 2015

Scientists map autism genetic pathway that regulates brain development

Scientists at the University of California, San Diego School of Medicine have found that mutations that cause autism in children are connected to a pathway that regulates brain development. The research, led by Lilia Iakoucheva, PhD, assistant professor in the Department of Psychiatry, is published in the February 18 issue of Neuron.

19 Feb 2015

Videos on resuscitation, assistive procedures may help patients make better end-of-life decisions

Most seriously ill elderly people who view video material about the pros and cons of available resuscitation and assistive procedures decide they would rather not receive such treatment when the time comes. So says Areej El-Jawahri of Massachusetts General Hospital and the Harvard Medical School in the US, lead author of a study in the Journal of General Internal Medicine, published by Springer.

19 Feb 2015

Medical Research News

Study provides new insights into early events that shape cancer

Particle sciences manufactures clinical supplies for Kinex’s glioblastom therapeutic

University of Alberta researcher named winner of A.S.P.E.N.'s 2015 Harry M. Vars Award

Researchers find potential new target to treat asthma patients

Possible cause of liver disease identified in adolescents with cystic fibrosis

UT Dallas study reports new gene therapy approach

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Study examines relationship between substance use and teen pregnancy

Study findings could lead to new potential drug targets for allergic diseases

INRS researchers explore cellular and molecular mechanisms that affect AgNP particles

NIAID expands Tuberculosis Research Units program to drive innovation in TB research

Duke researchers demonstrate genetic therapeutic technique to treat DMD patients

Weill Cornell receives NIH grant to study TB-causing bacteria

New plant-derived agent protects skin from harmful effects of UV irradiation

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

Ranibizumab drug reverses diabetes-related blindness

Rutgers researchers study rare form of gum disease that affects African-American adolescents

Researchers assemble comprehensive map of human epigenome

Scientists map autism genetic pathway that regulates brain development

Videos on resuscitation, assistive procedures may help patients make better end-of-life decisions

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