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Carbohydrate-binding proteins fill in gaps in immune defenses

Our bodies produce a family of proteins that recognize and kill bacteria whose carbohydrate coatings resemble those of our own cells too closely, scientists have discovered.

13 May 2014

Treating older men with early-stage prostate cancer does not help live longer

Treating older men with early-stage prostate cancer who also have other serious underlying health problems with aggressive therapies such as surgery or radiation therapy does not help them live longer and, in fact, can be detrimental, according to a study by UCLA researchers.

13 May 2014

Novel molecule prevents symptoms linked with allergen-induced asthma

A new study carried out by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham), the Max Planck Institute for Colloids and Interfaces (Germany), the Free University of Berlin (Germany), UC San Diego, and Shinshu University (Japan) has identified a novel molecule that prevents T-cells from orchestrating asthma brought on by allergens.

13 May 2014

Research may offer unique pathway for targeting new therapeutics for addiction treatment

A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai has published evidence that shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine.

13 May 2014

Wake Forest Baptist offers ways to minimize risks of motorcycle accidents

Riding a motorcycle, like most thrilling activities, comes with its own set of dangers. The Emergency Department at Wake Forest Baptist Medical Center alone treated 166 motorcycle-related cases during fiscal year 2013. Fifteen of those patients died from their injuries.

13 May 2014

Max Planck researchers elucidate important mechanism of protein folding

Proteins are the workhorses of the cell and thus responsible for almost all biological functions including metabolism, signal transmission or the determination of the cell's shape. However, before they can fulfill their various tasks, the chain-like molecules must first adopt an intricate three-dimensional conformation.

13 May 2014

Researchers use natural molecule to treat type 2 diabetes

Researchers at the Universit- Laval Faculty of Medicine, the Quebec Heart and Lung Institute Research Center, and the Institute of Nutrition and Functional Foods have discovered a natural molecule that could be used to treat insulin resistance and type 2 diabetes.

13 May 2014

Preconditioning crush increases survival rate of motor neurons after spinal root avulsion

A previous study showed that, 1 week after avulsion of the spinal nerve root, small motor neurons (< 500 μm2) negative for 27 kDa heat shock protein (HSP27) immunoreactivity died and only large (> 500 μm2) HSP27-positive motor neurons survived in the spinal cord ventral horn.

13 May 2014

2 genes work together to drive most lethal forms of prostate cancer

Two genes work together to drive the most lethal forms of prostate cancer, according to new research from the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center (CUMC).

13 May 2014

Beaumont Children's Hospital wins grant from CureSearch Children's Cancer to help fund therapeutic clinical trials

CureSearch for Children's Cancer has awarded a $20,000 grant to Beaumont Children's Hospital to help fund therapeutic clinical trials.

13 May 2014

Ill effects of blood pressure variability disputed

The effect of visit-to-visit blood pressure variability on mortality may be partly caused by changes in average values over time, say researchers.

12 May 2014

Inflammation may accentuate age-related bladder function decline

Age-associated biochemical changes in the bladder may accentuate the inflammation associated with overactive bladder, study findings indicate.

12 May 2014

Pelvic floor prolapse has unclear relationship with urinary symptoms

In women seeking treatment for pelvic floor problems, the severity of pelvic organ prolapse is not independently associated with lower urinary tract symptoms, a study by Spanish researchers has found.

12 May 2014

S. pneumoniae interacts with other nasopharyngeal bacteria

Streptococcus pneumoniae bacteria are able to detect and respond to other bacterial species in the same host niche, researchers report in Open Biology.

12 May 2014

Neuropathic pain features common in knee OA

Enough patients with knee osteoarthritis experience pain with neuropathic characteristics to warrant attempts to diagnose and classify these features, say researchers.

12 May 2014

Amrubicin promise for etoposide-naïve SCLC patients

Patients with chemotherapy-refractory small-cell lung cancer may benefit from treatment with the topoisomerase II inhibitor amrubicin, research from Japan suggests.

12 May 2014

Sports Authority, MRA partner to educate public about melanoma

Sports Authority, one of the nation's largest full-line sporting goods retailers, today announced that they have partnered with the Melanoma Research Alliance, the largest private funder of melanoma research, to inform the public about this deadly form of skin cancer and to raise funds to support studies aimed at its treatment and cure. This is the fourth consecutive year Sports Authority has participated in and supported the effort.

12 May 2014