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Factors predicting disengagement from psychosis early intervention identified

A study of first-episode psychosis patients in Hong Kong has found that those with fewer negative symptoms at presentation and poor medication compliance were more likely than others to disengage from an early intervention program.

21 Feb 2014

Altering sunitinib dosing schedule improves tolerability

Shortening the time that patients with advanced renal cell carcinoma are on and off treatment with sunitinib improves the drug’s overall tolerability without affecting its efficacy, say Japanese researchers.

21 Feb 2014

Advanced age should not preclude sunitinib use for mRCC

Elderly kidney cancer patients benefit from sunitinib therapy just as much as their younger counterparts, a retrospective analysis of six clinical trials shows.

21 Feb 2014

Non-coding RNAs linked to cancer and cancer survival

Several scientists, including one at Simon Fraser University, have made a discovery that strongly links a little understood molecule, which is similar to DNA, to cancer and cancer survival.

21 Feb 2014

People recount important memories that occur between the ages of 15 to 30

By the time most people are 25, they have made the most important memories of their lives, according to new research from the University of New Hampshire.

21 Feb 2014

New study uncovers mechanism of drug resistance

The use of antibiotics is often considered among the most important advances in the treatment of human disease. Unfortunately, though, bacteria are finding ways to make a comeback. According to the Centers for Disease Control, more than two million people come down with antibiotic-resistant infections annually, and at least 23,000 die because their treatment can’t stop the infection. In addition, the pipeline for new antibiotics has grown dangerously thin.

21 Feb 2014

Dreams and delusions are associated with faulty "reality testing", shows research

New research from the University of Adelaide has delved into the reasons why some people are unable to break free of their delusions, despite overwhelming evidence explaining the delusion isn't real.

21 Feb 2014

Research sheds light on pathological mechanisms that trigger psoriasis lesions

Streptococcal antigens (Streptococcus pyogenes) might be directly involved in the pathological mechanisms that result in the appearance of psoriasis lesions.

21 Feb 2014

Study on Zebrafish neurons could lead to better understanding of birth defects in humans

The zebrafish, a tropical freshwater fish similar to a minnow and native to the southeastern Himalayan region, is well established as a key tool for researchers studying human diseases, including brain disorders.

21 Feb 2014

Researchers discuss how psychology shapes human life

People and spaces, the tragedy of commonsense morality, myths about meaning of life, and remaking love were four themes at the Society for Personality and Social Psychology (SPSP) conference in Austin. Researchers presented new work, showing how psychology reaches into our everyday lives.

21 Feb 2014

Researchers develop new method to obtain three chemically different patches on same microparticle

Micromachines, nanorobots, multifunctional drug transporters, and matrices for tissue growth – these and many other applications would benefit from three-dimensional microstructures that present different (bio)chemical ligands that offer control over directionality. In the journal Angewandte Chemie, a team of German and American researchers has now reported the production of microparticles whose surface consists of three separate areas (“patches”) that can be decorated with three different (bio)molecules.

21 Feb 2014

Chewable drug candidate BTI320 can potentially prevent added sugar intake

It's official: sugar is not so sweet—for our health, that is. The new study "Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults," published in JAMA Internal Medicine, examines the intake of "added sugars," and the results suggest that sugar is now an independent risk factor for heart disease and other chronic diseases.

21 Feb 2014

Dyspnea during light daily activities used as indicator of exercise intolerance and low fitness

Dyspnea, a sensation of breathlessness, during light daily activities can be used as an indicator of exercise intolerance and low fitness. According to a study on Finnish twins, persistent or developing dyspnea reveals an increased risk of death.

21 Feb 2014

Ulcerative colitis patients not satisfied with current treatments according to new study

Patients with a serious type of inflammatory bowel disease, ulcerative colitis, are not satisfied with their current treatments and the majority do not have their disease under control, according to new research released today at the 9th Congress of the European Crohn’s and Colitis Organisation (ECCO) in Copenhagen. The majority (87.2 per cent) of the 250 patients with moderate to severe ulcerative colitis who were being treated with standard therapies failed to achieve control of their disease – defined either as going into remission or not having needed to use corticosteroid medications in the previous two months.1

21 Feb 2014

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

A large international study analyzing genes in tens of thousands of individuals has discovered 11 new genetic signals associated with blood pressure levels. Ten of those signals are in or very near genes encoding proteins that appear to be likely targets for drugs already in existence or in development.

21 Feb 2014

Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Oropharyngeal cancer patients treated with combined chemotherapy and radiation therapy reported a decrease in their voice and speech quality (VSQ) for up to one year after the completion of treatment, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

MATH biomarker with HPV status may provide improved outcomes in HNSCC patients

Evaluating next-generation sequencing (NGS) data and associated clinical records of head and neck squamous cell carcinoma (HNSCC) patients from several institutions, made available through The Cancer Genome Atlas (TCGA), showed that combining Mutant-Allele Tumor Heterogeneity (MATH) as a biomarker with the patient's HPV status provides an effective indicator of improved patient outcome, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Humidification of mouth during radiotherapy reduces hospital stay, mucositis in head, neck cancer patients

Patients who received daily humidification of the mouth and throat region beginning from day one of radiation therapy treatment spent nearly 50 percent fewer days in the hospital to manage their side effects, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

University of Texas researchers reveal ancient mysteries behind leprosy

Research at The University of Texas MD Anderson Cancer Center is finally unearthing some of the ancient mysteries behind leprosy, also known as Hansen's disease, which has plagued mankind throughout history.

21 Feb 2014

Medical Research News

Factors predicting disengagement from psychosis early intervention identified

Altering sunitinib dosing schedule improves tolerability

Advanced age should not preclude sunitinib use for mRCC

Non-coding RNAs linked to cancer and cancer survival

People recount important memories that occur between the ages of 15 to 30

New study uncovers mechanism of drug resistance

Dreams and delusions are associated with faulty "reality testing", shows research

Research sheds light on pathological mechanisms that trigger psoriasis lesions

Study on Zebrafish neurons could lead to better understanding of birth defects in humans

Researchers discuss how psychology shapes human life

Researchers develop new method to obtain three chemically different patches on same microparticle

Chewable drug candidate BTI320 can potentially prevent added sugar intake

Dyspnea during light daily activities used as indicator of exercise intolerance and low fitness

Ulcerative colitis patients not satisfied with current treatments according to new study

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

MATH biomarker with HPV status may provide improved outcomes in HNSCC patients

Humidification of mouth during radiotherapy reduces hospital stay, mucositis in head, neck cancer patients

University of Texas researchers reveal ancient mysteries behind leprosy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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