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Heritable bipolar phenotypes pinned down

A large study has pinpointed brain and behavioural traits that are genetically influenced and associated with bipolar I disorder.

14 Feb 2014

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial.

14 Feb 2014

Old FDA-approved drugs may hold promise for treatment of rare, drug-resistant cancer

University of Pittsburgh Cancer Institute (UPCI) scientists have shown that old drugs might be able to do new tricks.

14 Feb 2014

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

Long-term research that was initiated at UCLA's Jonsson Comprehensive Cancer Center on lymphatic mapping and sentinel-node biopsy, techniques for detecting the earliest spread (metastasis) of melanoma, the deadliest form of skin cancer, has confirmed that these techniques significantly prolong patients' disease-free and melanoma-specific survival over the traditional observational "watch and wait" techniques.

14 Feb 2014

Researchers receive funding to develop treatments for Rett Syndrome

Researchers from Scotland and the US are taking a step towards reversing the effects of a debilitating genetic disease and bring hope to tens of thousands of sufferers worldwide.

14 Feb 2014

University of Liège joins IMI programme to develop new antibiotics against Gram-negative pathogens

More than 30 European universities and companies, led by GlaxoSmithKline, are joining forces in a six-year programme funded by the Innovative Medicines Initiative (IMI) for the sum of EUR 85 millions with the aim of developing new antibiotics against Gram-negative pathogens.

14 Feb 2014

Novel method for determining diffusion coefficients of analytes in fluids and equilibrium constants of reactions

How strongly do two dissolved analytes react with each other? Such information is of paramount importance not only in chemistry and molecular biology, but also in medicine or pharmacy, where it is used, i.a., to determine optimal drug doses. A method developed in the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw will allow for determining diffusion coefficients of analytes in fluids and equilibrium constants of reactions - quickly, at low cost, and most importantly: universally.

14 Feb 2014

First record of direct link between Alzheimer's disease and elevated brain aluminium

Research at Keele University in Staffordshire, UK, has shown for the first time that an individual who was exposed to aluminium at work and died of Alzheimer's disease had high levels of aluminium in the brain.

14 Feb 2014

Researchers find 'missing' genetic risk in cancer

A new study could help to answer an important riddle in our understanding of genetics: why research to look for the genetic causes of common diseases has failed to explain more than a fraction of the heritable risk of developing them.

14 Feb 2014

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

A team of researchers from Case Western Reserve School of Medicine has discovered how the cancer-related protein Bcl-2 signals cancer cells to live longer.

14 Feb 2014

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of symptom onset does not improve stroke outcomes, according to research presented today at the American Stroke Association's International Stroke Conference.

14 Feb 2014

Researchers personalize drug treatments for cholangiocarcinoma using genomic sequencing

Physicians at Mayo Clinic's Individualized Medicine Clinic and researchers at the Translational Genomics Research Institute (TGen) have personalized drug treatments for patients with cholangiocarcinoma using genomic sequencing technologies.

14 Feb 2014

McGill University researcher receives 2014 Dan David Prize for contributions to science of memory, brain

Dr. Brenda Milner, an active researcher at the age of 95 at the Montreal Neurological Institute and Hospital, McGill University, has been awarded the 2014 Dan David Prize for her fundamental contributions to the science of memory and the brain.

14 Feb 2014

FDA approves IMRIS’ VISIUS Surgical Theatre that integrates high-field MR scanners

IMRIS Inc. today announced US Food and Drug Administration clearance of the newest generation VISIUS® Surgical Theatre which integrates Siemens' latest high-field MR scanners.

14 Feb 2014

Topiramate reduces drinking in patients committed to abstinence from alcohol

Heavy drinking alcohol consumption is common in the United States and takes a personal and societal toll, with an annual estimated cost of $223.5 billion due to losses in workplace productivity, and health care and criminal justice expenses.

14 Feb 2014

Researchers develop new model for isolating effects of nutrients on gene expression, physiology

Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression and physiology.

14 Feb 2014

NIST scientists receives ABC Best Paper Award 2013 from Springer

The Springer journal Analytical and Bioanalytical Chemistry (ABC) has chosen Sherrie Elzey (32) and De-Hao Tsai (37) as the recipients of its Best Paper Award 2013.

14 Feb 2014

New theory for how stem cells decide whether to become liver or pancreatic cells

Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in inflammation and pain.

14 Feb 2014

TSRI receives $2.3M to study long-term memory deficits that contribute to brain diseases

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $2.3 million from the National Institute of Mental Health to study the processes involved in long-term memory and how deficits in those processes contribute to brain diseases.

14 Feb 2014

Study reveals appearance-based video emphasizes teens to use sunscreen

After offering information about UV light and sun-protective behaviors, the two health-ed videos diverge: one describes the increased skin cancer risk of UV exposure and the other describes effects on appearance including wrinkles and premature aging.

14 Feb 2014

Medical Research News

Heritable bipolar phenotypes pinned down

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

Old FDA-approved drugs may hold promise for treatment of rare, drug-resistant cancer

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

Researchers receive funding to develop treatments for Rett Syndrome

University of Liège joins IMI programme to develop new antibiotics against Gram-negative pathogens

Novel method for determining diffusion coefficients of analytes in fluids and equilibrium constants of reactions

First record of direct link between Alzheimer's disease and elevated brain aluminium

Researchers find 'missing' genetic risk in cancer

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

Researchers personalize drug treatments for cholangiocarcinoma using genomic sequencing

McGill University researcher receives 2014 Dan David Prize for contributions to science of memory, brain

FDA approves IMRIS’ VISIUS Surgical Theatre that integrates high-field MR scanners

Topiramate reduces drinking in patients committed to abstinence from alcohol

Researchers develop new model for isolating effects of nutrients on gene expression, physiology

NIST scientists receives ABC Best Paper Award 2013 from Springer

New theory for how stem cells decide whether to become liver or pancreatic cells

TSRI receives $2.3M to study long-term memory deficits that contribute to brain diseases

Study reveals appearance-based video emphasizes teens to use sunscreen

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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