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Researchers find unique role for p66Shc adaptor protein in regulating glucose and cell growth

A protein that has been known until recently as part of a complex communications network within the cell also plays a direct role in regulating sugar metabolism, according to a new study published on-line in the journal Science Signaling (February 18, 2014).

14 Feb 2014

Two new mechanisms open alternative approaches to antibiotics development

The first mechanism disrupts the arrangement of amino acids required for the cohesion of the protease subunits. As a result the protease breaks into two parts. The second acts directly on the core of the active center.

14 Feb 2014

Loving relationship is good for heart, says cardiologist

With Valentine's Day just one day away, Vanderbilt Heart and Vascular Institute cardiologist Julie Damp, M.D., says being involved in a healthy, loving relationship is good for the heart.

14 Feb 2014

New approach for treating leukemia

A group of researchers at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression.

14 Feb 2014

Sarcopenia increases risk of sepsis risk in patients undergoing live donor liver transplantation

Japanese researchers have determined that sarcopenia—a loss of skeletal muscle mass—increases risk of sepsis and mortality risk in patients undergoing live donor liver transplantation.

14 Feb 2014

Indoor exposure to radon gas may cause of lung cancer

Pointing to startling statistics on lung cancer risks, child health and other experts in Canada are ramping up calls for families nationwide to test their homes for radon gas contamination.

14 Feb 2014

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Enhancing the brain's inherent ability to rebuild itself after a stroke with molecular components of stem cells holds enormous promise for treating the leading cause of long-term disability in adults.

14 Feb 2014

Researchers discover how beneficial bacteria in guts communicate with own cells

Communication is vital to any successful relationship. Researchers from the Institute of Food Research and the University of East Anglia have discovered how the beneficial bacteria in our guts communicate with our own cells.

14 Feb 2014

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Many psychiatric disorders are accompanied by memory deficits. Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

14 Feb 2014

Persons with severe symptoms of mental illness are at higher risk for being HIV-infected

People receiving mental health care are up to four times more likely to be infected with HIV than the general population, according to a new study published Feb. 13 in the American Journal of Public Health from researchers at Penn Medicine and other institutions who tested over 1,000 patients in care in Philadelphia and Baltimore.

14 Feb 2014

Exposure to common infections linked to memory and brain function

Exposure to common infections is linked to memory and brain function - even if the infections never made you ill, according to research presented at the American Stroke Association's International Stroke Conference 2014.

13 Feb 2014

Poor quality sleep may cause widespread pain later in life

Poor quality sleep may be partly responsible for the aches and pains people develop as they grow older, according to a study published in Arthritis & Rheumatology.

13 Feb 2014

Common mutations produce typical schizophrenia brain changes

Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows.

13 Feb 2014

Consistent mania monitoring during perinatal period warranted

Pregnant and postpartum women with bipolar disorder experience clinically severe symptoms, suggesting the need for continued monitoring of mania during this time, say researchers.

13 Feb 2014

Intravenous magnesium fails to improve stroke-related disability

Giving intravenous magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, according to research presented at the American Stroke Association's International Stroke Conference 2014

13 Feb 2014

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first high definition picture of the Cas9 complex - a key part of the CRISPR-Cas system used by scientists as a genome-editing tool to silence genes and probe the biology of cells. Their findings, which are reported this week in Cell, are expected to help researchers refine and further engineer the tool to accelerate genomic research and bring the technology closer to use in the treatment of human genetic disease.

13 Feb 2014

Researchers discover promising new approach for leukemia treatment

A group of researchers at the Institute for Research in Immunology and Cancer of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells that are the root cause of the disease, resistance to treatment and relapse.

13 Feb 2014

Moderate-intensity exercise reduces stroke risk in women

Women don't need to run marathons or do intense aerobics to reduce their stroke risk. Moderate-intensity exercise - such as brisk walking or playing tennis -- may do the trick, according to research presented at the American Stroke Association's International Stroke Conference 2014.

13 Feb 2014

New research identifies raised risk of self-harm among patients with certain physical illnesses

New research quantifying the risk of admission to hospital for self-harm has identified a raised risk of self-harm among groups of patients with certain physical illnesses. While it is known that psychiatric illnesses are associated with a greatly elevated risk of self-harm, a moderately elevated risk was seen with common physical illnesses such as diabetes, epilepsy and asthma.

13 Feb 2014

Heavy exposure to air pollution increases risk for developing hypertension during pregnancy

Breathing the air outside their homes may be just as toxic to pregnant women - if not more so - as breathing in cigarette smoke, increasing a mom-to-be's risk of developing deadly complications such as preeclampsia, according to findings from a new University of Florida study.

13 Feb 2014

Medical Research News

Researchers find unique role for p66Shc adaptor protein in regulating glucose and cell growth

Two new mechanisms open alternative approaches to antibiotics development

Loving relationship is good for heart, says cardiologist

New approach for treating leukemia

Sarcopenia increases risk of sepsis risk in patients undergoing live donor liver transplantation

Indoor exposure to radon gas may cause of lung cancer

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Researchers discover how beneficial bacteria in guts communicate with own cells

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Persons with severe symptoms of mental illness are at higher risk for being HIV-infected

Exposure to common infections linked to memory and brain function

Poor quality sleep may cause widespread pain later in life

Common mutations produce typical schizophrenia brain changes

Consistent mania monitoring during perinatal period warranted

Intravenous magnesium fails to improve stroke-related disability

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

Researchers discover promising new approach for leukemia treatment

Moderate-intensity exercise reduces stroke risk in women

New research identifies raised risk of self-harm among patients with certain physical illnesses

Heavy exposure to air pollution increases risk for developing hypertension during pregnancy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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