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Report highlights recommendations to advance safety of childbirth in Indonesia

Indonesia is a fast-rising economic power that has made significant progress toward key development goals including reducing child mortality. But for reasons outlined in a National Academy of Sciences report by U.S. and Indonesian experts, the nation's estimated rates of maternal and neonatal mortality remain tragically high.

31 Jan 2014

Scientists discover potential cure for triple negative breast cancer

Scientists have discovered a potential cure for one of the most aggressive and least treatable forms of breast cancer called "triple negative breast cancer." In laboratory experiments involving human cancer cells, scientists used a virus similar to the one that helped eradicate smallpox to coax cancer cells to produce a protein which makes them susceptible to radioactive iodine.

31 Jan 2014

New insight into how gut bacteria digest fibre

New insight into how gut bacteria digest fibre could lead to advances in areas as diverse as health and environmentally-friendly biofuels.

31 Jan 2014

Findings support link between psychological well-being and physical health

In a comprehensive review published in the current issue of P&P Carol Ryff described how major research findings have supported the link between psychological well-being and physical health.

31 Jan 2014

More than 1/3 of women experience hot flashes for 10 years after menopause

A team of researchers from the Perelman School of Medicine at the University of Pennsylvania has found that moderate to severe hot flashes continue, on average, for nearly five years after menopause, and more than a third of women experience moderate/severe hot flashes for 10 years or more after menopause.

31 Jan 2014

Core stabilization exercise in stroke patients could be enhanced by real-time video feedback

About 80% of stroke survivors experience hemiparesis, which causes weakness or the inability to move one side of the body. Core stabilization exercise to improve postural stability and independent walking in chronic hemiparetic stroke patients could be enhanced by real-time video feedback, report researchers in Restorative Neurology and Neuroscience.

31 Jan 2014

Prediction models can be useful for heart team to determine best treatment strategy

Detailed prediction models that project long-term patient mortality following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) surgery can be useful for the heart team when determining the best treatment strategy for individual patients, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

31 Jan 2014

Doctor offers tips for fans who suddenly have to face months without football

After the final play of the Super Bowl, millions of fans will go through withdrawal symptoms from not being able to watch football for months.

31 Jan 2014

Look to heart shaped foods to protect heart

The crumbs from the Christmas cookies are gone and black-eyed peas, eaten on New Year to bring luck, are a distant memory. Declared American Heart Month with Valentine's Day smack dab in the middle, February is here. What to eat to keep your heart healthy?

31 Jan 2014

Study points to gender-specific mechanisms of brain repair following oxygen deprivation

Physicians have long known that oxygen deprivation to the brain around the time of birth causes worse damage in boys than girls. Now a study by researchers from the Johns Hopkins Children’s Center conducted in mice reveals one possible reason behind this gender disparity and points to gender-specific mechanisms of brain repair following such injury.

31 Jan 2014

Researchers identify components of C. diff bacteria that can be used to develop better treatment

Rhode Island Hospital researchers have identified components in Clostridium difficile (C. diff) that may lead to new diagnostic tools, and ultimately more timely and effective treatment for this often fatal infection. C. diff is a spore-forming bacterium that causes severe diarrhea and is responsible for 14,000 deaths annually in the U.S. The study is published online in advance of print in the Journal of Molecular Diagnostics.

31 Jan 2014

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

The Nairobi-based International Livestock Research Institute announced today that a global consortium supported by the Bill & Melinda Gates Foundation has been formed to develop a new vaccine against a disease that's devastating cattle herds in sub-Saharan Africa. This highly advanced cattle vaccine project could also help malaria and cancer research in humans.

31 Jan 2014

Researchers identify potential genes that can be targeted for new treatments for hepatocellular cancer

Patients with advanced hepatocellular (or liver) cancer have high mortality rates, with existing drugs demonstrating only a small, but significant survival advantage. By combining a zebrafish model of liver cancer with data from human tumors, researchers from the Icahn School of Medicine at Mount Sinai hope to identify potential genes of interest that can be targeted for new treatments for hepatocellular carcinoma, the most common form of liver cancer to develop from liver cells.

31 Jan 2014

UC San Diego researchers uncover causes for hereditary spastic paraplegia

In a study published in the January 31, 2014 issue of Science, an international team led by scientists at the University of California, San Diego School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia. HSP is characterized by progressive stiffness and contraction of the lower limbs and is associated with epilepsy, cognitive impairment, blindness and other neurological features.

31 Jan 2014

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

Age is a key risk factor for breast cancer. A recent study by researchers from the Dartmouth-Hitchcock Norris Cotton Cancer Center, "Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation," examines the connection between cancer and the aging process to see if epigenetic DNA alterations might contribute to age-related increases in breast cancer risk.

31 Jan 2014

Large amounts of choline may be needed to support fetal development during pregnancy

Recent research published in the American Journal of Clinical Nutrition found that during pregnancy, and particularly during the third trimester, large amounts of choline may be needed to support fetal development. Conclusions of the research revealed that current recommendations may be too low. Choline deficiency in pregnant women may result in elevated levels of homocysteine, potentially resulting in birth defects.

31 Jan 2014

Finding could lead to new treatments for osteoporosis

Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that occur when the body doesn't make enough bone.

31 Jan 2014

Llama-derived antibodies open door to development of new treatments for C. difficile infections

Researchers from the Alberta Glycomics Centre at the University of Calgary and the University of Alberta, in collaboration with researchers at the National Research Council of Canada in Ottawa, have revealed the first molecular views showing how highly specific antibodies derived from llamas may provide a new method for controlling deadly infections from the opportunistic bacterial pathogen Clostridium difficile (C. difficile).

31 Jan 2014

New biological pathway-based computational model to identify genetic links with diseases

Dartmouth researchers developed a new biological pathway-based computational model, called the Pathway-based Human Phenotype Network (PHPN), to identify underlying genetic connections between different diseases as reported in BioDataMining this week.

31 Jan 2014

More antipsychotic medications prescribed to children and adolescents in Germany

Increasing numbers of children and adolescents are being given antipsychotic drugs in Germany, as Christian Bachmann and colleagues found out in a study published in the current issue of Deutsches -rzteblatt International (Dtsch Arztebl Int 2014; 111(3): 25 - 40). The authors used routine insurance data of the Barmer GEK statutory health insurance company to analyze antipsychotic prescriptions for this age group from 2005 to 2012.

31 Jan 2014

Medical Research News

Report highlights recommendations to advance safety of childbirth in Indonesia

Scientists discover potential cure for triple negative breast cancer

New insight into how gut bacteria digest fibre

Findings support link between psychological well-being and physical health

More than 1/3 of women experience hot flashes for 10 years after menopause

Core stabilization exercise in stroke patients could be enhanced by real-time video feedback

Prediction models can be useful for heart team to determine best treatment strategy

Doctor offers tips for fans who suddenly have to face months without football

Look to heart shaped foods to protect heart

Study points to gender-specific mechanisms of brain repair following oxygen deprivation

Researchers identify components of C. diff bacteria that can be used to develop better treatment

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

Researchers identify potential genes that can be targeted for new treatments for hepatocellular cancer

UC San Diego researchers uncover causes for hereditary spastic paraplegia

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

Large amounts of choline may be needed to support fetal development during pregnancy

Finding could lead to new treatments for osteoporosis

Llama-derived antibodies open door to development of new treatments for C. difficile infections

New biological pathway-based computational model to identify genetic links with diseases

More antipsychotic medications prescribed to children and adolescents in Germany

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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